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BİTLİS YÖRESİNDEN ALINAN BAZI BALLARIN BOTANİK VE BİYOKİMYASAL PROFİLİ

Yıl 2020, Cilt: 44 Sayı: 3, 494 - 505, 30.09.2020
https://doi.org/10.33483/jfpau.767197

Öz

Amaç: Bu makalede 2017 yılında Bitlis bölgesinden rastgele seçilen 4 bal örneğinin polen kompozisyonunu ve antioksidan aktivitesini değerlendirmeyi amaçladık.
Gereç ve Yöntem: Melisopalinolojik analizde asetolizsiz standart protokol kullanılmıştır. Numunelerin antioksidan aktivitesi, 1,1-difenil-2-pikrilhidrazil serbest radikal giderme aktivitesi (DPPH), hidrojen peroksit giderme aktivitesi (HPSA), demirli iyon şelat aktiviteleri (FICA), 2,2'-azino-bis-3-etilbenztiyazolin-6-sülfonik asit radikal katyon temizleme deneyleri (ABTS) ve ferrik indirgeyici antioksidan güç deneyleri (FRAP) gibi birkaç in vitro yöntem kullanılarak değerlendirilmiştir.
Sonuç ve Tartışma: 4 balın polen kompozisyonu değerlendirildiğinde balların multifloral olduğu görülmüştür. Elde edilen sonuçlar, antioksidan aktivitesinin baldan bala belirgin bir şekilde değiştiğini göstermiştir. ABTS ve FICA örnekleri birbirlerinden biraz farklı, DPPH, HPSA ve FRAP sırasıyla 54.45 - 387.60 ug / mL, 212.11 - 246.64 ug / mL ve % 47.20 - 78.23 arasında bulunmuştur. Ek olarak, toplam fenol ve toplam flavonoid içerikleri belirlenmiştir. Örnekler kıyaslandığında 3, en yüksek fenolik ve flavonoid içeriği (626.48 mg GAE / 100 g ve 4.4 mg CAE / 100 g-etanol) göstermiştir. Hemen hemen tüm numunelerin iyi bir antioksidan kaynağı olduğu tespit edilmiştir.

Kaynakça

  • 1. Pasupuleti, V. R., Sammugam, L., Ramesh, N., and Gan, S. H., (2017). Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative medicine and cellular longevity, 1259510-1259510.
  • 2. Temizer, İ. K., Türkmen, Z., and Güder, A., (2019). Assessment of Palynological Characterization and Total Phenol-Flavonoid Content of Some Honeys from Ordu in Turkey. 12(3), 1275-1282.
  • 3. Dżugan, M., Sowa, P., Kwaśniewska, M., Wesołowska, M., and Czernicka, M., (2017). Physicochemical Parameters and Antioxidant Activity of Bee Honey Enriched With Herbs. Plant Foods for Human Nutrition, 72(1), 74-81.
  • 4. Temizer, İ. K., Güder, A., and Çelemli, Ö. G., (2016). Botanic Origin, Various Physicochemical and Antioxidant Properties of Honey Samples From Giresun, Turkey. Hacettepe Journal of Biology and Chemistry, 44(3), 209-215.
  • 5. Behçet, L., (1991). Süphan Dağı (Bitlis) Florası. Yüzüncü Yıl Üniversitesi, Fen Bilimleri Enstitüsü Dergisi, 1(1), 29-38.
  • 6. Altan, Y. and Behçet, L., (1995). Hizan (Bitlis) Florası. Turk Journal of Botany, 19 (3 ), 331-344.
  • 7. Altıok, A., Bitlis Çayı Havzası Florası, in Fen Bilimleri Enstitüsü. 2004, Yüzüncü Yıl Üniversitesi.
  • 8. Çelik, T., Kesan Deresi (Bitlis) Florası, in Fen Bilimleri Enstitüsü. 2006, Yüzüncü Yıl Üniversitesi.
  • 9. Keser, A. M. and Özgökçe, F., (2019). The Flora of Karz (Garez) Mountain (Tatvan, Bitlis/ Turkey). Biological Diversity and Conservation, 12(2), 78-91.
  • 10. Santos-Sánchez, N. F., Salas-Coronado, R., Villanueva-Cañongo, C., and Hernández-Carlos, B., Antioxidant Compounds and Their Antioxidant Mechanism, in Antioxidants, E. Shalaby, Editor. 2019, IntechOpen: London.
  • 11. Louveaux, J., Maurizio, A., and Vorwohl, G., (1978). Methods of Melissopalynology. Bee World, 59(4), 139-157.
  • 12. Song, X.-Y., Yao, Y.-F., and Yang, W.-D., (2012). Pollen Analysis of Natural Honeys from the Central Region of Shanxi, North China. PLOS ONE, 7(11), e49545.
  • 13. Gür, M., Güder, A., Verep, D., Güney, K., Özkan, O. E., Seki, N., and Kandemirli, F., (2018). Some Important Plants for Epilepsy Treatment: Antioxidant Activity and Flavonoid Compositions. Iranian Journal of Science and Technology, Transactions A: Science, 42(4), 1847-1857.
  • 14. Ateş, S., Gür, M., Özkan, O. E., Akça, M., Olgun, Ç., and Güder, A., (2015). Chemical Contents and Antifungal Activity of Some Durable Wood Extractives vs. Pleurotus ostreatus. 2015, 10(2), 11.
  • 15. Blois, M. S., (1958). Antioxidant Determinations by the Use of a Stable Free Radical. Nature, 181(4617), 1199-1200.
  • 16. Ruch, R. J., Cheng, S.-j., and Klaunig, J. E., (1989). Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis, 10(6), 1003-1008.
  • 17. Dinis, T. C. P., Madeira, V. M. C., and Almeida, L. M., (1994). Action of Phenolic Derivatives (Acetaminophen, Salicylate, and 5-Aminosalicylate) as Inhibitors of Membrane Lipid Peroxidation and as Peroxyl Radical Scavengers. Archives of Biochemistry and Biophysics, 315(1), 161-169.
  • 18. Gökce, H., Alpaslan, Y. B., Zeyrek, C. T., Ağar, E., Güder, A., Özdemir, N., and Alpaslan, G., (2019). Structural, spectroscopic, radical scavenging activity, molecular docking and DFT studies of a synthesized Schiff base compound. Journal of Molecular Structure, 1179, 205-215.
  • 19. Oyaizu, M., (1986). Studies on products of browning reaction antioxidative activities of products of browning reaction prepared from glucosamine. The Japanese Journal of Nutrition and Dietetics, 44(6), 307-315.
  • 20. Antonie, I., (2014). The biodiversity of the melliferous plants in the surroundings of the town sebes (alba county) and their economical importance Scientific Papers Series Management, Economic Engineering in Agriculture and Rural Development 14(4), 13-18.
  • 21. Farkas, A. and Zajacz, E., (2007). Nectar production for the Hungarian honey industry. The European Journal Plant Science and Biotechnology, 1(2), 125-151.
  • 22. Çelemli, Ö. G., Özenirler, Ç., Bayram, N. E., Zare, G., and Sorkun, K., (2018). Melissopalynological analysis for geographical marking of Kars honey. Kafkas Universitesi Veteriner Fakultesi Dergisi, 24(1), 53-59.
  • 23. Al-Hindi, R. R. and Shehata, A., (2014). Evaluation of antioxidant and antibacterial activities and essential elements content of locally produced honey in Saudi Arabia. Life Science Journal, 11, 175-185.
  • 24. Kıvrak, Ş. and Kıvrak, İ., (2017). Assessment of phenolic profile of Turkish honeys. International Journal of Food Properties, 20(4), 864-876.
  • 25. Alzahrani, H. A., Boukraa, L., Bellik, Y., Abdellah, F., Bakhotmah, B. A., Kolayli, S., and Sahin, H., (2012). Evaluation of the antioxidant activity of three varieties of honey from different botanical and geographical origins. Global journal of health science, 4(6), 191-196.
  • 26. Temizer, İ. K., Güder, A., Temel, F. A., and Cüce, H., (2018). Antioxidant activities and heavy metal contents of Castanea sativa honey. Global NEST Journal, 20(3), 541-550.
  • 27. Sherin, M. S., Benny, B., and Ashadevi, S., (2015). Antioxidant Activity, DNA and Cellular Protective Effect of Honey from Srilanka. Asian Journal of Biochemistry, 10(3), 106-116.
  • 28. Salgueiro, F. B., Lira, A. F., Rumjanek, V. M., and Castro, R. N., (2014). Phenolic composition and antioxidant properties of Brazilian honeys. Quím. Nova, 37(5), 821-826.
  • 29. Pontis, J. A., Costa, L. A. M. A. d., Silva, S. J. R. d., and Flach, A., (2014). Color, phenolic and flavonoid content, and antioxidant activity of honey from Roraima, Brazil. Food Sci. Technol (Campinas), 34(1), 69-73.
  • 30. Al-Hindi, R. R. and Shehata, A., (2014). Evaluation of Antioxidant and Antibacterial Activities and Essential Elements Content of Locally Produced Honey in Saudi Arabia. 11(5), 175-185.
  • 31. Yegin, S. Ç., Alver, D. O., Çiçek, F., and Güder, A., (2018). Investigation of Antioxidant and Antimicrobial Activity of Different Multifloral Honeys. Mellifera, 18(2), 7-14.
  • 32. Silici, S. and Ülgen, N., (2019). Bioactive Properties of Blossom and Honeydew Honeys Mellifera, 19(2), 41-52.
  • 33. Juszczak, L., Gałkowska, D., Ostrowska, M., and Socha, R., (2016). Antioxidant activity of honey supplemented with bee products. Natural Product Research, 30(12), 1436-1439.
  • 34. Dżugan, M., Tomczyk, M., Sowa, P., and Grabek-Lejko, D., (2018). Antioxidant Activity as Biomarker of Honey Variety. Molecules, 3(8): 2069.
  • 35. Stagos, D., Soulitsiotis, N., Tsadila, C., Papaeconomou, S., Arvanitis, C., Ntontos, A., Karkanta, F., Adamou‑Androulaki, S., Petrotos, K., Spandidos, D. A., Kouretas, D., and Mossialos, D., (2018). Antibacterial and antioxidant activity of different types of honey derived from Mount Olympus in Greece. International Journal of Molecular Medicine 42(2), 726-734.
  • 36. Moniruzzaman, M., Yung An, C., Rao, P. V., Hawlader, M. N. I., Azlan, S. A. B. M., Sulaiman, S. A., and Gan, S. H., (2014). Identification of Phenolic Acids and Flavonoids in Monofloral Honey from Bangladesh by High Performance Liquid Chromatography: Determination of Antioxidant Capacity. BioMed Research International, 2014, 737490.
  • 37. Nayik, G. A. and Nanda, V., (2016). A chemometric approach to evaluate the phenolic compounds, antioxidant activity and mineral content of different unifloral honey types from Kashmir, India. LWT, 74, 504-513.
  • 38. Temizer, İ. K., Güder, A., Temel, F. A., and Avcı, E., (2018). A comparison of the antioxidant activities and biomonitoring of heavy metals by pollen in the urban environments. Environmental Monitoring and Assessment, 190(8), 462.
  • 39. Temizer, İ. K., Güder, A., and Başer, B., (2020). Botanic Origin and Antioxidant Activity of Some Bitlis Honeys. The Black Sea Journal of Sciences, 10(1), 121-130.

DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES

Yıl 2020, Cilt: 44 Sayı: 3, 494 - 505, 30.09.2020
https://doi.org/10.33483/jfpau.767197

Öz

Objective: In this paper, we aimed to evaluate the pollen composition and antioxidant activity of 4 randomly selected honey samples from the Bitlis region in 2017.
Material and Method: The melisopalynological analysis was used standard protocol without acetolysis. The antioxidant activity of samples were evaluated using several in vitro methods, 1,1-diphenyl-2-picrylhydrazyl free radical scavenging activity (DPPH), hydrogen peroxide scavenging activity (HPSA), Ferrous ions chelating activities (FICA), 2,2’-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid radical cation scavenging assays (ABTS) and the ferric reducing antioxidant power assays (FRAP).
Result and Discussion: All the samples were determined as multifloral honey. Outcomes obtained declared that the antioxidant activity changed remarkably from honey to honey. ABTS and FICA of samples differ slightly each other’s. DPPH, HPSA, and FRAP were ranged from between 54.45 – 387.60 µg/mL, 212.11 – 246.64 µg/mL and 47.20 – 78.23 %, respectively. In addition, total phenol and total flavonoid contents were determined. Comparatively, Sample 3 showed highest levels of phenolic and flavonoid content (626.48 mg GAE/100 g and 4.4 mg CAE/100 g, respectively) in ethanol extract. Almost all the samples are well source for antioxidants.

Kaynakça

  • 1. Pasupuleti, V. R., Sammugam, L., Ramesh, N., and Gan, S. H., (2017). Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative medicine and cellular longevity, 1259510-1259510.
  • 2. Temizer, İ. K., Türkmen, Z., and Güder, A., (2019). Assessment of Palynological Characterization and Total Phenol-Flavonoid Content of Some Honeys from Ordu in Turkey. 12(3), 1275-1282.
  • 3. Dżugan, M., Sowa, P., Kwaśniewska, M., Wesołowska, M., and Czernicka, M., (2017). Physicochemical Parameters and Antioxidant Activity of Bee Honey Enriched With Herbs. Plant Foods for Human Nutrition, 72(1), 74-81.
  • 4. Temizer, İ. K., Güder, A., and Çelemli, Ö. G., (2016). Botanic Origin, Various Physicochemical and Antioxidant Properties of Honey Samples From Giresun, Turkey. Hacettepe Journal of Biology and Chemistry, 44(3), 209-215.
  • 5. Behçet, L., (1991). Süphan Dağı (Bitlis) Florası. Yüzüncü Yıl Üniversitesi, Fen Bilimleri Enstitüsü Dergisi, 1(1), 29-38.
  • 6. Altan, Y. and Behçet, L., (1995). Hizan (Bitlis) Florası. Turk Journal of Botany, 19 (3 ), 331-344.
  • 7. Altıok, A., Bitlis Çayı Havzası Florası, in Fen Bilimleri Enstitüsü. 2004, Yüzüncü Yıl Üniversitesi.
  • 8. Çelik, T., Kesan Deresi (Bitlis) Florası, in Fen Bilimleri Enstitüsü. 2006, Yüzüncü Yıl Üniversitesi.
  • 9. Keser, A. M. and Özgökçe, F., (2019). The Flora of Karz (Garez) Mountain (Tatvan, Bitlis/ Turkey). Biological Diversity and Conservation, 12(2), 78-91.
  • 10. Santos-Sánchez, N. F., Salas-Coronado, R., Villanueva-Cañongo, C., and Hernández-Carlos, B., Antioxidant Compounds and Their Antioxidant Mechanism, in Antioxidants, E. Shalaby, Editor. 2019, IntechOpen: London.
  • 11. Louveaux, J., Maurizio, A., and Vorwohl, G., (1978). Methods of Melissopalynology. Bee World, 59(4), 139-157.
  • 12. Song, X.-Y., Yao, Y.-F., and Yang, W.-D., (2012). Pollen Analysis of Natural Honeys from the Central Region of Shanxi, North China. PLOS ONE, 7(11), e49545.
  • 13. Gür, M., Güder, A., Verep, D., Güney, K., Özkan, O. E., Seki, N., and Kandemirli, F., (2018). Some Important Plants for Epilepsy Treatment: Antioxidant Activity and Flavonoid Compositions. Iranian Journal of Science and Technology, Transactions A: Science, 42(4), 1847-1857.
  • 14. Ateş, S., Gür, M., Özkan, O. E., Akça, M., Olgun, Ç., and Güder, A., (2015). Chemical Contents and Antifungal Activity of Some Durable Wood Extractives vs. Pleurotus ostreatus. 2015, 10(2), 11.
  • 15. Blois, M. S., (1958). Antioxidant Determinations by the Use of a Stable Free Radical. Nature, 181(4617), 1199-1200.
  • 16. Ruch, R. J., Cheng, S.-j., and Klaunig, J. E., (1989). Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis, 10(6), 1003-1008.
  • 17. Dinis, T. C. P., Madeira, V. M. C., and Almeida, L. M., (1994). Action of Phenolic Derivatives (Acetaminophen, Salicylate, and 5-Aminosalicylate) as Inhibitors of Membrane Lipid Peroxidation and as Peroxyl Radical Scavengers. Archives of Biochemistry and Biophysics, 315(1), 161-169.
  • 18. Gökce, H., Alpaslan, Y. B., Zeyrek, C. T., Ağar, E., Güder, A., Özdemir, N., and Alpaslan, G., (2019). Structural, spectroscopic, radical scavenging activity, molecular docking and DFT studies of a synthesized Schiff base compound. Journal of Molecular Structure, 1179, 205-215.
  • 19. Oyaizu, M., (1986). Studies on products of browning reaction antioxidative activities of products of browning reaction prepared from glucosamine. The Japanese Journal of Nutrition and Dietetics, 44(6), 307-315.
  • 20. Antonie, I., (2014). The biodiversity of the melliferous plants in the surroundings of the town sebes (alba county) and their economical importance Scientific Papers Series Management, Economic Engineering in Agriculture and Rural Development 14(4), 13-18.
  • 21. Farkas, A. and Zajacz, E., (2007). Nectar production for the Hungarian honey industry. The European Journal Plant Science and Biotechnology, 1(2), 125-151.
  • 22. Çelemli, Ö. G., Özenirler, Ç., Bayram, N. E., Zare, G., and Sorkun, K., (2018). Melissopalynological analysis for geographical marking of Kars honey. Kafkas Universitesi Veteriner Fakultesi Dergisi, 24(1), 53-59.
  • 23. Al-Hindi, R. R. and Shehata, A., (2014). Evaluation of antioxidant and antibacterial activities and essential elements content of locally produced honey in Saudi Arabia. Life Science Journal, 11, 175-185.
  • 24. Kıvrak, Ş. and Kıvrak, İ., (2017). Assessment of phenolic profile of Turkish honeys. International Journal of Food Properties, 20(4), 864-876.
  • 25. Alzahrani, H. A., Boukraa, L., Bellik, Y., Abdellah, F., Bakhotmah, B. A., Kolayli, S., and Sahin, H., (2012). Evaluation of the antioxidant activity of three varieties of honey from different botanical and geographical origins. Global journal of health science, 4(6), 191-196.
  • 26. Temizer, İ. K., Güder, A., Temel, F. A., and Cüce, H., (2018). Antioxidant activities and heavy metal contents of Castanea sativa honey. Global NEST Journal, 20(3), 541-550.
  • 27. Sherin, M. S., Benny, B., and Ashadevi, S., (2015). Antioxidant Activity, DNA and Cellular Protective Effect of Honey from Srilanka. Asian Journal of Biochemistry, 10(3), 106-116.
  • 28. Salgueiro, F. B., Lira, A. F., Rumjanek, V. M., and Castro, R. N., (2014). Phenolic composition and antioxidant properties of Brazilian honeys. Quím. Nova, 37(5), 821-826.
  • 29. Pontis, J. A., Costa, L. A. M. A. d., Silva, S. J. R. d., and Flach, A., (2014). Color, phenolic and flavonoid content, and antioxidant activity of honey from Roraima, Brazil. Food Sci. Technol (Campinas), 34(1), 69-73.
  • 30. Al-Hindi, R. R. and Shehata, A., (2014). Evaluation of Antioxidant and Antibacterial Activities and Essential Elements Content of Locally Produced Honey in Saudi Arabia. 11(5), 175-185.
  • 31. Yegin, S. Ç., Alver, D. O., Çiçek, F., and Güder, A., (2018). Investigation of Antioxidant and Antimicrobial Activity of Different Multifloral Honeys. Mellifera, 18(2), 7-14.
  • 32. Silici, S. and Ülgen, N., (2019). Bioactive Properties of Blossom and Honeydew Honeys Mellifera, 19(2), 41-52.
  • 33. Juszczak, L., Gałkowska, D., Ostrowska, M., and Socha, R., (2016). Antioxidant activity of honey supplemented with bee products. Natural Product Research, 30(12), 1436-1439.
  • 34. Dżugan, M., Tomczyk, M., Sowa, P., and Grabek-Lejko, D., (2018). Antioxidant Activity as Biomarker of Honey Variety. Molecules, 3(8): 2069.
  • 35. Stagos, D., Soulitsiotis, N., Tsadila, C., Papaeconomou, S., Arvanitis, C., Ntontos, A., Karkanta, F., Adamou‑Androulaki, S., Petrotos, K., Spandidos, D. A., Kouretas, D., and Mossialos, D., (2018). Antibacterial and antioxidant activity of different types of honey derived from Mount Olympus in Greece. International Journal of Molecular Medicine 42(2), 726-734.
  • 36. Moniruzzaman, M., Yung An, C., Rao, P. V., Hawlader, M. N. I., Azlan, S. A. B. M., Sulaiman, S. A., and Gan, S. H., (2014). Identification of Phenolic Acids and Flavonoids in Monofloral Honey from Bangladesh by High Performance Liquid Chromatography: Determination of Antioxidant Capacity. BioMed Research International, 2014, 737490.
  • 37. Nayik, G. A. and Nanda, V., (2016). A chemometric approach to evaluate the phenolic compounds, antioxidant activity and mineral content of different unifloral honey types from Kashmir, India. LWT, 74, 504-513.
  • 38. Temizer, İ. K., Güder, A., Temel, F. A., and Avcı, E., (2018). A comparison of the antioxidant activities and biomonitoring of heavy metals by pollen in the urban environments. Environmental Monitoring and Assessment, 190(8), 462.
  • 39. Temizer, İ. K., Güder, A., and Başer, B., (2020). Botanic Origin and Antioxidant Activity of Some Bitlis Honeys. The Black Sea Journal of Sciences, 10(1), 121-130.
Toplam 39 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Eczacılık ve İlaç Bilimleri
Bölüm Araştırma Makalesi
Yazarlar

İlginç Kizilpinar Temizer 0000-0003-0425-5898

Aytaç Güder 0000-0002-1190-8749

Birol Başer 0000-0002-9305-8759

Yayımlanma Tarihi 30 Eylül 2020
Gönderilme Tarihi 9 Temmuz 2020
Kabul Tarihi 29 Eylül 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 44 Sayı: 3

Kaynak Göster

APA Kizilpinar Temizer, İ., Güder, A., & Başer, B. (2020). DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES. Journal of Faculty of Pharmacy of Ankara University, 44(3), 494-505. https://doi.org/10.33483/jfpau.767197
AMA Kizilpinar Temizer İ, Güder A, Başer B. DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES. Ankara Ecz. Fak. Derg. Eylül 2020;44(3):494-505. doi:10.33483/jfpau.767197
Chicago Kizilpinar Temizer, İlginç, Aytaç Güder, ve Birol Başer. “DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES”. Journal of Faculty of Pharmacy of Ankara University 44, sy. 3 (Eylül 2020): 494-505. https://doi.org/10.33483/jfpau.767197.
EndNote Kizilpinar Temizer İ, Güder A, Başer B (01 Eylül 2020) DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES. Journal of Faculty of Pharmacy of Ankara University 44 3 494–505.
IEEE İ. Kizilpinar Temizer, A. Güder, ve B. Başer, “DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES”, Ankara Ecz. Fak. Derg., c. 44, sy. 3, ss. 494–505, 2020, doi: 10.33483/jfpau.767197.
ISNAD Kizilpinar Temizer, İlginç vd. “DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES”. Journal of Faculty of Pharmacy of Ankara University 44/3 (Eylül 2020), 494-505. https://doi.org/10.33483/jfpau.767197.
JAMA Kizilpinar Temizer İ, Güder A, Başer B. DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES. Ankara Ecz. Fak. Derg. 2020;44:494–505.
MLA Kizilpinar Temizer, İlginç vd. “DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES”. Journal of Faculty of Pharmacy of Ankara University, c. 44, sy. 3, 2020, ss. 494-05, doi:10.33483/jfpau.767197.
Vancouver Kizilpinar Temizer İ, Güder A, Başer B. DETERMINATION OF SEVERAL BITLIS HONEYS BASED ON THEIR BOTANIC AND BIOCHEMICAL PROFILES. Ankara Ecz. Fak. Derg. 2020;44(3):494-505.

Kapsam ve Amaç

Ankara Üniversitesi Eczacılık Fakültesi Dergisi, açık erişim, hakemli bir dergi olup Türkçe veya İngilizce olarak farmasötik bilimler alanındaki önemli gelişmeleri içeren orijinal araştırmalar, derlemeler ve kısa bildiriler için uluslararası bir yayım ortamıdır. Bilimsel toplantılarda sunulan bildiriler supleman özel sayısı olarak dergide yayımlanabilir. Ayrıca, tüm farmasötik alandaki gelecek ve önceki ulusal ve uluslararası bilimsel toplantılar ile sosyal aktiviteleri içerir.