PETROSELINUM CRISPUM (MILL.) FUSS (MAYDANOZ), GIDA VE TIBBİ OLARAK ÖNEMLİ BİR BİTKİ: 2013-2023 ARASINDAKİ SON ÇALIŞMALARIN DERLEMESİ

Yıl 2024, Cilt: 48 Sayı: 2, 727 - 750, 20.05.2024

Tuğba Subaş , Ufuk Özgen , İçim Gökkaya , Gülin Renda

https://doi.org/10.33483/jfpau.1362626

Öz

Amaç: Petroselinum crispum (Mill.) Fuss, neredeyse dünyanın her yerinde yetişen, iki yıllık, parlak yeşil renkli, tıbbi ve aromatik bir bitkidir. Günümüzde en çok kullanılan mutfak bitkilerinden biridir. Gıda olarak kullanımının yanı sıra çeşitli in vivo ve in vitro çalışmalarda geniş farmakolojik aktivitelere sahip olduğu gösterilmiştir. Bu çalışmada maydanozun geleneksel kullanımı, fitokimyasal bileşimi, farmakolojik aktiviteleri, klinik çalışmaları, toksisitesi ve ilaç etkileşimleri üzerine yapılan güncel çalışmaların kapsamlı bir şekilde özetlenmesi amaçlanmıştır.
Sonuç ve Tartışma: Literatür verilerine göre maydanoz diüretik, karminatif, emenagog olarak, böbrek taşı oluşumunun önlenmesi ve tedavisi, idrar yolu enfeksiyonları ve mide rahatsızlıkları gibi rahatsızlıkların tedavisi için kullanılmaktadır. Fitokimyasal bileşimi flavonoitler, kumarinler, fenolik bileşikler, organik asitler, karotenoitler, vitaminler, mineraller, sabit yağ, uçucu yağ ve diğer bileşiklerden oluşmaktadır. P. crispum üzerinde yapılan çalışmalar, antioksidan, antibakteriyel, antifungal, antidiyabetik, antihipertansif, antiplatelet, analjezik, antiinflamatuar, antihepatotoksik, antinefrotoksik, antikanser, antiürolitiyatik, yara iyileştirici, antiobezite, östrojenik ve nöroprotektif etkiler dahil olmak üzere çok çeşitli farmakolojik aktivitelere sahip olduğunu göstermiştir. Bu derleme, P. crispum'a ilişkin son on yıla (2013-2023) ait bilimsel verileri kapsamlı bir şekilde özetlemektedir.

Anahtar Kelimeler

Farmakoloji, fitokimya, geleneksel, maydanoz, Petroselinum crispum

PETROSELINUM CRISPUM (MILL.) FUSS (PARSLEY), A FOOD AND MEDICINALLY IMPORTANT PLANT: A REVIEW OF RECENT STUDIES BETWEEN 2013-2023

Öz

Objective: Petroselinum crispum (Mill.) Fuss is a bright green biennial medicinal and aromatic herb that grows almost all over the world. Today, it is one of the most commonly used culinary herbs. In addition to its use as food, it has been shown to possess broad pharmacological activities in several in vivo and in vitro studies. This study aimed to comprehensively summarize the current studies on the traditional use, phytochemical composition, pharmacological activities, clinical studies, toxicity, and drug interactions of parsley.
Result and Discussion: According to the literature data, parsley is used as a diuretic, carminative, emmenagogue and for the prevention and treatment of kidney stone formation, the treatment of conditions such as urinary tract infections and stomach disorders. Its phytochemical composition consists of flavonoids, coumarins, phenolic compounds, organic acids, carotenoids, vitamins, minerals, fixed oil, essential oil, and other compounds. Studies on P. crispum have shown that it has a wide range of pharmacological activities, including antioxidant, antibacterial, antifungal, antidiabetic, antihypertensive, antiplatelet, analgesic, antiinflammatory, antihepatotoxic, antinephrotoxic, anticancer, antiurolithiatic, wound healing, antiobesity, estrogenic and neuroprotective effects. This review comprehensively summarizes the scientific data of the last ten years (2013-2023) on P. crispum.

Anahtar Kelimeler

Parsley, Petroselinum crispum, pharmacology, phytochemistry, traditional

Etik Beyan

The authors declare that ethics committee approval is not mandatory for this study.

Kaynakça

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