Ratlarda Rasyona Katılan Glütenlerin Serum Lipid Profili Üzerine Etkisi

Öz

Bu çalışmada ratların rasyonunaprotein kaynağı olarak katılan soya küspesi, mısır ve buğday glütenlerinin total kolesterol, trigliserit, düşük dansiteli lipoprotein (LDL), yüksek dansiteli lipoprotein (HDL) ve çok düşük dansiteli lipoprotein (VLDL) seviyeleri üzerine etkilerinin belirlenmesi amaçlandı. Araştırmada 20 günlük toplam 24 adet erkek rat kullanıldı ve üç grup (her grupta 8 rat) oluşturuldu. Grup1’de rasyonda protein kaynağı olarak yüksek oranda soya küspesi, Grup2’de rasyonda protein kaynağı olarak yüksek oranda mısır glüteni ve Grup3’te rasyonda protein kaynağı olarak yüksek oranda buğday glüteni kullanıldı. Çalışmanın sonunda hayvanlardan kan serumları alındı ve analizleri yapıldı. Çalışmada serum kolesterol ve HDL seviyelerinin Grup2’de önemli oranda azaldığı tespit edildi.Bununla birlikte serum trigliserit ve VLDL seviyelerinin Grup3’te önemli oranda arttığı, serum LDL seviyesinin ise tüm gruplarda azaldığı belirlendi. Sonuç olarak rasyona katılan mısır ve buğday glütenlerinin erkek ratlarda lipid profilini kısmen etkilediği söylenebilir.

Anahtar Kelimeler

• Glüten
• Lipid Profili
• Rat
• Serum

Effect of Dietary Glutens on Lipid Profile in Rats

Öz

This study was aimed to determine the effectiveness in diet which content of soybean meal, corn and wheat glutens of rats on serum total cholesterol, triglycerides, low density lipoproteins (LDL), high density lipoproteins (HDL) and very low density lipoproteins (VLDL). In this study, a total of 24 male rats were used which were 20 days old aged. In the study, groups were designed in 3 groups (8 animals in each group); The Group1 which used of soybean meal as a protein source in diet, the Group2 which used of corn gluten as a protein source in diet and the Group3 which used of wheat gluten as a protein source in diet as respectively. Sera were taken from the animals at the end of the experiment and analyses were performed. In this study, the levels of serum cholesterol and HDL were decreased significantly in the Group2. Furthermore, the levels of serum triglycerides and VLDL were significantly increased in the Group3, while the level of serum LDL was found similarly in all groups. As a conclusion, it is point out that the wheat and corn gluten in dietary may partially affect the lipid profile of the male rats.

Anahtar Kelimeler

• Gluten
• Lipid Profile
• Rat
• Serum

Kaynakça

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