Covid-19 Pandemisinde İmmünonütrientlerin Önemi: Arjinin, Glutamin ve Omega-3 Yağ Asitleri

Öz

İlk kez Çin’in Vuhan şehrinde Aralık 2019 tarihinde görülüp Mart 2020 tarihinde WHO tarafından pandemi olarak bildirilen koronavirüs salgını o tarihten bu yana tüm dünyayı etkisi altına almıştır. Koronavirüs hastalığı yeni tip koronavirüs olarak adlandırılan SARS-Cov-2 virüsünün neden olduğu, soğuk algınlığı semptomları, zatüre, çoklu organ yetmezliği, yaygın damar içi pıhtılaşma gibi semptomları bulunan ve ölümcül olabilen bir hastalıktır. Şu anda Covid-19 enfeksiyonunun tedavisinde antiviral, antibakteriyel, antimalaryal ajanlar kullanılmaktadır. Bunun yanı sıra DNA-RNA bazlı, viral vektör tabanlı, inaktif virüs gibi SARS-CoV-2 aşıları geliştirilmiş ve geliştirilmeye devam etmektedir. Öte yandan bağışıklığın güçlenmesinde son derece etkin olan bazı immünonutrientler, Covid-19 enfeksiyonunun seyrinin iyileşmesinde ve semptomlarının hafiflemesinde ön plana çıkmaktadır. Bu derleme yazıda, arjinin, glutamin ve omega-3 yağ asitlerinin Covid-19 enfeksiyonundaki etkinliğinin incelendiği çalışmalar ile ulusal/uluslararası kılavuzlar ele alınmıştır.

Anahtar Kelimeler

• Covid-19
• İmmünonütrientler
• Arjinin
• Glutamin
• Omega-3

The Importance of Immunonutrients in The Covid-19 Pandemic: Arginine, Glutamine and Omega-3 Fatty Acids

Öz

The coronavirus epidemic, which was first seen in Wuhan, China in December 2019 and reported as a pandemic by WHO in March 2020, has affected the whole world since then. Coronavirus disease is a disease caused by the SARS-Cov-2 virus, called the new type of coronavirus, with symptoms such as cold symptoms, pneumonia, multi-organ failure, disseminated intravascular coagulation, and can be fatal. Currently, antiviral, antibacterial, antimalarial agents are used in the treatment of Covid-19 infection. In addition, DNA-RNA-based, viral vector-based, SARS-CoV-2 vaccines such as inactivated virus have been developed and continue to be developed. On the other hand, some immunonutrients, which are extremely effective in strengthening immunity, come to the fore in improving the course of Covid-19 infection and alleviating its symptoms. In this review article, studies examining the effectiveness of arginine, glutamine and omega-3 fatty acids in Covid-19 infection and national/international guidelines are discussed.

Anahtar Kelimeler

• Covid-19
• Immunonutrients
• Arginine
• Glutamine
• Omega-3

Kaynakça

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