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DETERMINATION OF CLOMIPRAMINE HYDROCHLORIDE FROM ITS COMMERCIAL DRUG FORM BY VOLTAMMETRY

Yıl 2018, Cilt 2, Sayı 1, 1 - 8, 31.01.2018

Öz

Kaynakça

  • REFERENCES
  • BIOSHIP, E., HUSSEIN, W.,1984, Electroanalytical study of tricyclic antidepressants, Analyst, 109, 73-80. ÇITAK, M., YILMAZ, S., DILGIN, Y., TÜRKER, G., YAĞMUR, S., ERDUGAN, H., 2007, Osteryoung square wave voltammetric determination of phenazopyridine hydrochloride in human urine and tablet dosage forms based on electrochemical reduction at carbon paste electrode.Current Pharmaceutical Analysis, 3, 141-145. EKER, R., YILMAZ, S., YAĞMUR, S., TONGUC YAYINTAS, O., 2017, Voltammetric determination of clozapine from its drug form. Journal of Scientific Perspectives, 2, 19-30. GUIYING, Y., JIN, F., L. KONG, J., 2007, Sensitive Determination of Clomipramine at Poly-ABSA/Pt Nano-Clusters Modified Gşassy Carbon Electrode. Analytical Letters, 40(18), 3392-3404 HUANG, F., QU, S., ZHANG, S., LIU, B., Kong D, J., 2008, Sensitive voltammetric detection of clomipramine at 16-mercaptohexadecanoic acid self-assembled monolayer modified gold electrode. Microchimica Acta, 161, 149-155. IVANDIDI, TA.,SARADA, BV., TERASHIMA, C., RAO, TN.,TRYK, DA., ISHIGURO, H., KUBOTA, Y., FUJISHIMA, A., 2002, Electrochemical detection of tricyclic antidepressant drugs by HPLC using highly boron-doped diamond electrodes. J Electroanal Chem, 521, 117-126. ORTUNO, J A., HERNANDEZ, J., PEDRENO, C S., 2006, Ion-selective electrode for the determination of some multidrug resistance reversers. Sens Actuators, B119, 282-287. SKRZYPEK, S., CIESIELSKI, W, SOKOLOWSKI, A., YILMAZ, S., KAZMIERCAK, D., 2005, TALANTA, 66, 1146-1151. YAGMUR, S., TURE, M., SAGLIKOGLU, G., SADIKOGLU, M.,YILMAZ, S., 2017, The Quantitative Detection of Phenylephrine in Pharmaceutical Preparations and Spiked Human Urine by Voltammetry, Journol of Russian electrochemistry (in press). YILMAZ, S., SADIKOGLU, M., SAGLIKOGLU, G., YILDIZ, M., YENGIN, C., KILINC, E., 2013, Electrooxidation of Phenazopyridine Hydrochloride and its Voltammetric and HPLC Determination in Human Urine and Tablet Dosage Form, Int. J. Electrochem. Sci., 8, 6818-6828.

DETERMINATION OF CLOMIPRAMINE HYDROCHLORIDE FROM ITS COMMERCIAL DRUG FORM BY VOLTAMMETRY

Yıl 2018, Cilt 2, Sayı 1, 1 - 8, 31.01.2018

Öz

In this study, electroanalytical technique was developed for the quantitative analysis of clomipramine hydrochloride from its commercial tablet dosage forms based on its oxidation behavior. The electrochemical determination of clomipramine hydrochloride was easily carried out on glassy carbon electrode (GCE) by two voltammetric techniques.  The electrochemical measurements were carried out on GCE surface in different buffer solutions in the pH range from 2.00 to 12.00 by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques.  The effect of pH on the anodic peak current and peak potential was investigated. Phosphate buffer (pH 6.50) was selected for analytical purposes.  The diffusion-controlled nature of the peak was obtained.   A linear calibration plot for DPV analysis was constructed in the clozapine concentration range from 5x10-6 mol L-1 to 3x10-5 mol L-1. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 2.8x10-7 mol L-1 and 8.4x10-7 mol L-1 respectively. 

Kaynakça

  • REFERENCES
  • BIOSHIP, E., HUSSEIN, W.,1984, Electroanalytical study of tricyclic antidepressants, Analyst, 109, 73-80. ÇITAK, M., YILMAZ, S., DILGIN, Y., TÜRKER, G., YAĞMUR, S., ERDUGAN, H., 2007, Osteryoung square wave voltammetric determination of phenazopyridine hydrochloride in human urine and tablet dosage forms based on electrochemical reduction at carbon paste electrode.Current Pharmaceutical Analysis, 3, 141-145. EKER, R., YILMAZ, S., YAĞMUR, S., TONGUC YAYINTAS, O., 2017, Voltammetric determination of clozapine from its drug form. Journal of Scientific Perspectives, 2, 19-30. GUIYING, Y., JIN, F., L. KONG, J., 2007, Sensitive Determination of Clomipramine at Poly-ABSA/Pt Nano-Clusters Modified Gşassy Carbon Electrode. Analytical Letters, 40(18), 3392-3404 HUANG, F., QU, S., ZHANG, S., LIU, B., Kong D, J., 2008, Sensitive voltammetric detection of clomipramine at 16-mercaptohexadecanoic acid self-assembled monolayer modified gold electrode. Microchimica Acta, 161, 149-155. IVANDIDI, TA.,SARADA, BV., TERASHIMA, C., RAO, TN.,TRYK, DA., ISHIGURO, H., KUBOTA, Y., FUJISHIMA, A., 2002, Electrochemical detection of tricyclic antidepressant drugs by HPLC using highly boron-doped diamond electrodes. J Electroanal Chem, 521, 117-126. ORTUNO, J A., HERNANDEZ, J., PEDRENO, C S., 2006, Ion-selective electrode for the determination of some multidrug resistance reversers. Sens Actuators, B119, 282-287. SKRZYPEK, S., CIESIELSKI, W, SOKOLOWSKI, A., YILMAZ, S., KAZMIERCAK, D., 2005, TALANTA, 66, 1146-1151. YAGMUR, S., TURE, M., SAGLIKOGLU, G., SADIKOGLU, M.,YILMAZ, S., 2017, The Quantitative Detection of Phenylephrine in Pharmaceutical Preparations and Spiked Human Urine by Voltammetry, Journol of Russian electrochemistry (in press). YILMAZ, S., SADIKOGLU, M., SAGLIKOGLU, G., YILDIZ, M., YENGIN, C., KILINC, E., 2013, Electrooxidation of Phenazopyridine Hydrochloride and its Voltammetric and HPLC Determination in Human Urine and Tablet Dosage Form, Int. J. Electrochem. Sci., 8, 6818-6828.

Ayrıntılar

Birincil Dil İngilizce
Konular Temel Bilimler
Bölüm Makaleler
Yazarlar

Elif UĞURLU Bu kişi benim

Türkiye


Sultan YAĞMUR> (Sorumlu Yazar)
Çanakkale Onsekiz Mart University, Çanakkale, Turkey
0000-0002-2329-2451


Selehattin YILMAZ>
aCanakkale, Turkey, Canakkale Onsekiz Mart University, Faculty of Sciences and Arts,

Yayımlanma Tarihi 31 Ocak 2018
Yayınlandığı Sayı Yıl 2018, Cilt 2, Sayı 1

Kaynak Göster

APA Uğurlu, E. , Yağmur, S. & Yılmaz, S. (2018). DETERMINATION OF CLOMIPRAMINE HYDROCHLORIDE FROM ITS COMMERCIAL DRUG FORM BY VOLTAMMETRY . Journal of Scientific Perspectives , 2 (1) , 1-8 . Retrieved from https://dergipark.org.tr/tr/pub/jsp/issue/36400/410434