QTL Analysis Methods
Öz
In recent years, quantitative characters have settled to a quite important place among genetic studies. The inheritance of these traits is usually achieved by multiple gene expression and by the additive and interactive effects of these genes. Therefore, the analysis methods used to understand the genetic basis of quantitative traits may be more complex than those of qualitative traits. The loci on the chromosome at which the genes controlling the genetic architecture of the quantitative traits are located are called the quantitative trait loci (QTL). There are different methods for detecting and analyzing the presence of these loci. In addition, it is possible to map the QTLs with the help of the molecular markers as a developing method thanks to today's technology. In this review, the methods of diagnosing QTL and mapping studies were analyzed.
Anahtar Kelimeler
Kaynakça
- [1] W. R. Doerge, “Mapping and analysis of quantitative trait loci in experimental populations,” Nature, vol. 3, pp. 43-52, Jan. 2002. DOI: 10.1038/nrg703
- [2] D. S. M. Falconer and T. F. C. Mackay, “Quantitative trait loci” in Introduction To Quantitative Genetics, 4th ed., Essex, England, 1996, pp. 356-377.
- [3] H. Geldermann, “Investigations on inheritance of quantitative characters in animals by gene markers I. methods,” Theoretical and Applied Genetics, vol. 46, no. 7, pp. 319-330, 1975.
- [4] C.S. Haley and S.A. Knott, “A simple regression method for mapping quantitative trait loci in line crosses using flanking markers,” Heredity, vol. 69, pp. 315-324, 1992.
- [5] B. İşçi, “Asmada QTL (kantitatif karakter lokus) analizi,” Anadolu (Journal of Aegean Agricultural Research Institute), vol. 18, no. 2, pp. 11-37, 2008.
- [6] R. C. Jansen, “Interval mapping of multiple quantitative trait loci,” Genetics, vol. 135, pp. 205-211, Sep. 1993.
- [7] R. C. Jansen, D. L. Johnson and J. A. M. Van Arendonk, “A mixture model approach to the mapping of quantitative trait loci in complex populations with an application to multiple cattle families,” Genetics, vol. 148, pp. 391-399, Jan. 1998.
- [8] O. Kavuncu, “İstatistik Teorisi ve Teorik Dağılımlar”, Ankara, Turkey, 1995.
Ayrıntılar
Birincil Dil
İngilizce
Konular
-
Bölüm
Derleme
Yayımlanma Tarihi
27 Haziran 2019
Gönderilme Tarihi
13 Mayıs 2019
Kabul Tarihi
22 Mayıs 2019
Yayımlandığı Sayı
Yıl 2019 Cilt: 5 Sayı: 1