Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity

Nurhan Gümrükçüoğlu; Bahar Bilgin Sökmen

doi:10.31466/kfbd.481807

TR EN

Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity

Öz

Schiff bases have excellent characteristics, structural similarities with natural biological agents and synthetic flexibility. Schiff base-bimolecular condensation products with aldehydes of primary amines represent valuable intermediates in organic synthesis. Schiff bases derived from salicylaldehyde have been reported to have plant growth regulator, antimicrobial or antimycotic activity. In studies describing the relationship between quantitative structure-antitumor activity of a series of Schiff bases, Salicyldehydes have been shown to provide the best correlation in the ligands. In this study, 6 new Schiff bases were synthesized from the reaction of the substituted amino compounds with 5-bromosalicylaldehyde and their structures were illuminated spectroscopic data. The biological activities of this compound series were evaluated. The results show that the novel compounds synthesized have effective antioxidant and antiurease activities.

Anahtar Kelimeler

1 2 4‐Triazole‐3‐one, 5-Bromosalicylaldehyde, Amino Compounds, Antioxidant Activity, Antiurease Activity

Kaynakça

References
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Ayrıntılar

Birincil Dil

İngilizce

Konular

Mühendislik

Bölüm

Araştırma Makalesi

Yazarlar

Nurhan Gümrükçüoğlu ^*
Türkiye

Bahar Bilgin Sökmen

Yayımlanma Tarihi

31 Aralık 2018

Gönderilme Tarihi

13 Kasım 2018

Kabul Tarihi

4 Aralık 2018

Yayımlandığı Sayı

Yıl 2018 Cilt: 8 Sayı: 2

DOI

https://doi.org/10.31466/kfbd.481807

IZ

https://izlik.org/JA67MF69XD

APA

Gümrükçüoğlu, N., & Bilgin Sökmen, B. (2018). Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity. Karadeniz Fen Bilimleri Dergisi, 8(2), 171-180. https://doi.org/10.31466/kfbd.481807

AMA

1.Gümrükçüoğlu N, Bilgin Sökmen B. Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity. KFBD. 2018;8(2):171-180. doi:10.31466/kfbd.481807

Chicago

Gümrükçüoğlu, Nurhan, ve Bahar Bilgin Sökmen. 2018. “Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity”. Karadeniz Fen Bilimleri Dergisi 8 (2): 171-80. https://doi.org/10.31466/kfbd.481807.

EndNote

Gümrükçüoğlu N, Bilgin Sökmen B (01 Aralık 2018) Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity. Karadeniz Fen Bilimleri Dergisi 8 2 171–180.

IEEE

[1]N. Gümrükçüoğlu ve B. Bilgin Sökmen, “Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity”, KFBD, c. 8, sy 2, ss. 171–180, Ara. 2018, doi: 10.31466/kfbd.481807.

ISNAD

Gümrükçüoğlu, Nurhan - Bilgin Sökmen, Bahar. “Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity”. Karadeniz Fen Bilimleri Dergisi 8/2 (01 Aralık 2018): 171-180. https://doi.org/10.31466/kfbd.481807.

JAMA

1.Gümrükçüoğlu N, Bilgin Sökmen B. Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity. KFBD. 2018;8:171–180.

MLA

Gümrükçüoğlu, Nurhan, ve Bahar Bilgin Sökmen. “Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity”. Karadeniz Fen Bilimleri Dergisi, c. 8, sy 2, Aralık 2018, ss. 171-80, doi:10.31466/kfbd.481807.

Vancouver

1.Nurhan Gümrükçüoğlu, Bahar Bilgin Sökmen. Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity. KFBD. 01 Aralık 2018;8(2):171-80. doi:10.31466/kfbd.481807

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Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity

Bazı Yeni 1,2,4‐Triazole‐3‐on Türevlerinin Sentezi ve Biyolojik Aktivitelerinin İncelenmesi

Öz

Anahtar Kelimeler

Synthesis of Some New 1,2,4‐Triazole‐3‐one Derivatives and Investigation of Biological Activity

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

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