A Simple MRI-Based Visual Guide To Differentiate Alzheimer’s Disease From Mild Cognitive İmpairment
Abstract
Objective: To distinguish between mild cognitive impairment (MCI) and Alzheimer’s disease (AD) by visual assessment of the length of the hippocampus
in magnetic resonance imaging (MRI).
Material and Methods: Consecutive patients diagnosed with MCI and AD were retrospectively searched on the Hospital Information Management Systems. MRI was rated for hippocampal atrophy defining with and without loss of hippocampal length. Patients with loss of hippocampal height were classified
as having AD by the clinical investigator, and the diagnosis of the patients was checked on the system.
Results: A total of 56 memory clinic patients with AD (n=14) and MCI (n=42) were included in the study. AD patients had significantly more hippocampal
atrophy than MCI patients (χ2=6.222, df=0.13, p=0.013).
Conclusion: There is a complex issue in the differential diagnosis between MCI and AD. A simple glace to the MRI may give a brief opinion to the physician in the clinic routine
Keywords
Alzheimer’s disease , mild cognitive impairment , hippocampus , MRI
Kaynakça
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