Overview of Sarcopenia and Associated Factors

Yıl 2023, Cilt: 18 Sayı: 3, 99 - 104, 20.11.2023

Tuba Tülay Koca , Buket Tuğan Yıldız

https://doi.org/10.17517/ksutfd.1225196

Öz

Sarcopenia is a progressive and generalized skeletal muscle disorder involving accelerated loss of muscle mass and function. Physical activity and nutrition are the main ways to prevent sarcopenia. The diagnosis of sarcopenia is based on muscle mass measurements and functional tests that assess muscle strength or physical performance. The pathogenesis of sarcopenia is complex and multifactorial.
In the absence of pharmacological drugs in the treatment of the disease in sarcopenic patients, non-pharmacological methods appear as the only option. Pharmacological treatment recommendations include vitamin D, testosterone, estrogens, protein and amino acids, growth hormone, fatty acids, vitamins and minerals. New researches continues in this area. Physical activity alone or in combination with protein supplementation has been shown to be effective in preventing disability and fragility in older people by increasing muscle mass and strength

Anahtar Kelimeler

sarcopenia, fraility, geriatrics

Sarkopeni’ye Genel Bakış ve İlişkili Faktörler

Öz

Sarkopeni akselere kas kütle ve fonksiyon kaybını içeren progresif ve generalize kas iskelet bozukluğudur. Fiziksel aktivite ve beslenme sarkopeni önlenmesinde ana yollardır. Sarkopeni tanısı, kas kütle ölçümlerine ve kas gücünü veya fiziksel performansı değerlendiren fonksiyonel testlere dayanır. Sarkopeni patogenezi kompleks ve multifaktöryeldir.
Sarkopenik hastalarda hastalığın tedavisinde farmakolojik ilaçların yokluğunda non-farmakolojik önlemler tek seçenek olarak karşımıza çıkmaktadır. Farmakolojik tedavi önerilerinde, vitamin D, testosteron, östrojenler, protein ve aminoasitler, büyüme hormonu, yağ asitleri, vitamin ve mineralleri içermektedir. Bu alanda yeni araştırmalar devam etmektedir. Fiziksel aktivitenin tek başına veya protein suplementasyonuyla birlikte ileri yaş kişilerde engellilik ve kırılganlığı önlemede kas kütlesi ve kuvvetini artırma yoluyla efektif olduğu gösterilmiştir.

Anahtar Kelimeler

sarkopeni, kırılganlık, geriatri

Kaynakça

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