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Huzursuz Bacak Sendromlu Hastalarda Tibial Sinir İletimi

Yıl 2021, , 236 - 244, 31.08.2021
https://doi.org/10.24938/kutfd.868709

Öz

Amaç: Huzursuz bacak sendromunun patogenez ve klinik korelasyonları çok çeşitlidir. Sendromun nöropati kliniği ile prezentasyonu kafa karıştırıcı olabilir. Bu çalışmanın amacı, huzursuz bacak sendromlu hastalarda alt ekstremite sinir iletilerini gözden geçirmek ve olası farklılıkları belirlemektir.
Gereç ve Yöntemler: Huzursuz bacak sendromu ve ek semptomlarının sorgulandığı bataryaya göre 32 huzursuz bacak sendromu tanısı alan ve tedavisi devam eden hastaların kesitsel olarak alt ekstremite distal sinir iletileri değerlendirildi. Motor ve duyu siniri iletileri standart protokol ile gerçekleştirildi. Dopamin agonisti tedavisi devam eden huzursuz bacak sendromu hastalarının demografik, klinik özellikleri ile sinir iletileri değerlendirildi. Sonuçlar sağlıklı kontrol grubu (n=29) ile karşılaştırıldı.
Bulgular: Tüm hastaların nörolojik muayeneleri normal sınırlardaydı. Her iki grup yaş ve cinsiyet olarak benzer özellikteydi. Hasta grubunda peroneal ve sural sinir ileti parametreleri sağlıklı kontrol grubu ile kıyaslanınca farklılık göstermiyordu (p>0.05). Ancak tibial sinir parametrelerine bakıldığında kontrol grubuna göre amplitüdde azalma ve distal latansta uzama olduğu görüldü (p=0.003, p<0.001). Tibial sinir ileti hızının da hasta grubunda daha yavaş olduğunu bulduk (p<0.001).
Sonuç: Sonuçlar göstermektedir ki huzursuz bacak sendromu hastalarında tibial sinir ileti parametreleri kontrol grubuna göre değişebilir. Huzursuz bacak sendromu hastalarının kullandıkları tedaviyi tekrarlamadan önce, etiyolojik aydınlatma daha önce yapılmış bile olsa optimal tedavi planı için tetkiklerin yenilenmesinin önemli olabileceği unutulmamalıdır.

Proje Numarası

yok

Kaynakça

  • 1. Akyol A, Kiylioglu N, Kadikoylu G, Bolaman AZ, Ozgel N. Iron deficiency anemia and restless legs syndrome: is there an electrophysiological abnormality? Clin Neurol Neurosurg. 2003;106(1):23-7.
  • 2. Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walters AS, Winkelman JW et al. Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria–history, rationale, description, and significance. Sleep Med. 2014;15(8):860-73.
  • 3. Trenkwalder C, Allen R, Högl B, Paulus W, Winkelmann J. Restless legs syndrome associated with major diseases: a systematic review and new concept. Neurology. 2016;86(14):1336-43.
  • 4. Michaud M, Lavigne G, Desautels A, Poirier G, Montplaisir J. Effects of immobility on sensory and motor symptoms of restless legs syndrome. Mov Disord. 2002;17(1):112-5.
  • 5. Trenkwalder C, Bucher SF, Oertel WH. Electrophysiological pattern of involuntary limb movements in the restless legs syndrome. Muscle Nerve. 1996;19(2):155-62.
  • 6. Fulda S, Wetter TC. Emerging drugs for restless legs syndrome. Expert opinion on emerging drugs. 2005;10(3):537-52.
  • 7. Satija P, Ondo WG. Restless legs syndrome: pathophysiology, diagnosis and treatment. CNS Drugs. 2008;22(6):497-518.
  • 8. Ondo W, Jankovic J. Restless legs syndrome: clinicoetiologic correlates. Neurology. 1996;47(6):1435-41.
  • 9. Polydefkis M, Allen R, Hauer P, Earley CJ, Griffin J, McArthur JC. Subclinical sensory neuropathy in late-onset restless legs syndrome. Neurology. 2000;55(8):1115-21.
  • 10. Iannacone S, Ferrini-Strambi L, Zucconi M. Peripheral nerve investigation in restless legs syndrome. J Neurol. 1994;241(Suppl 1):S156.
  • 11. Nineb A, Rosso C, Dumurgier J, Nordine T, Lefaucheur JP, Creange A. Restless legs syndrome is frequently overlooked in patients being evaluated for polyneuropathies. Eur J Neurol. 2007;14(7):788-92.
  • 12. Teive HA, Munhoz RP, Barbosa ER. Professor Karl-Axel Ekbom and restless legs syndrome. Parkinsonism Relat Disord. 2009;15(4):254-7.
  • 13. Montplaisir J, Godbout R, Boghen D, DeChamplain J, Young S, Lapierre G. Familial restless legs with periodic movements in sleep: electrophysiologic, biochemical, and pharmacologic study. Neurology. 1985;35(1):130-4.
  • 14. Gonzalez-Latapi P, Malkani R. Update on restless legs syndrome: from mechanisms to treatment. Curr Neurol Neurosci Rep. 2019;19(8):1-12.
  • 15. Bastia JK, Bhoi SK, Kalita J, Misra UK. Neuropathy in a cohort of restless leg syndrome patients. J Clin Neurosci. 2015;22(8):1314-8.
  • 16. Preston DC, Shapiro BE. Electromyography and neuromuscular disorders e-book: clinical-electrophysiologic correlations. 3th ed. Netherlands. Elsevier Saunders, 2012.
  • 17. Allen RP, Bharmal M, Calloway M. Prevalence and disease burden of primary restless legs syndrome: results of a general population survey in the United States. Mov Disord. 2011;26(1):114-20.
  • 18. Hartmann M, Pfister R, Pfadenhauer K. Restless legs syndrome associated with spinal cord lesions. J Neurol Neurosurg Psychiatry. 1999;66(5):688-9.
  • 19. Freeman AA, Rye DB. The molecular basis of restless legs syndrome. Curr Opin Neurobiol. 2013;23(5):895-900.
  • 20. Pitarokoili K, Fels M, Kerasnoudis A, Tönges L, Gold R, Yoon MS. High‐resolution nerve ultrasound and electrophysiological findings in restless legs syndrome. J Neuroimaging. 2018;28(5):506-14.
  • 21. Rajabally YA, Shah RS. Restless legs syndrome in chronic inflammatory demyelinating polyneuropathy. Muscle Nerve. 2010;42(2):252-6.
  • 22. Hanewinckel R, Drenthen J, van Oijen M, Hofman A, van Doorn PA, Ikram MA. Prevalence of polyneuropathy in the general middle-aged and elderly population. Neurology. 2016;87(18):1892-8.
  • 23. Bastia JK, Bhoi SK, Kalita J, Misra UK. Neuropathy in a cohort of restless leg syndrome patients. J Clin Neurosci. 2015;22(8):1314-8.
  • 24. Anderson JC, Fritz ML, Benson JM, Tracy BL. Nerve decompression and restless legs syndrome: a retrospective analysis. Front Neurol. 2017;6(8):287.
  • 25. Kocabicak E, Terzi M, Akpinar K, Paksoy K, Cebeci I, Iyigun O. Restless leg syndrome and sleep quality in lumbar radiculopathy patients. Behav Neurol. 2014;2014:245358.
  • 26. Becker PM, Novak M. Diagnosis, comorbidities, and management of restless legs syndrome. Curr Med Res Opin. 2014;30(8):1441-60.
  • 27. Sethi KD, Mehta SH. A clinical primer on restless legs syndrome: what we know, and what we don't know. Am J Manag Care. 2012;18(5 Suppl):S83-8.
  • 28. Mastaglia FL. Tibial nerve entrapment in the popliteal fossa. Muscle Nerve. 2000;23(12):1883-6.
  • 29. Neary KC, Chang E. Tarsal tunnel syndrome secondary to accessory musculature: a case report. Foot Ankle Spec. 2019;12(6):549-54.

TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME

Yıl 2021, , 236 - 244, 31.08.2021
https://doi.org/10.24938/kutfd.868709

Öz

Objective: Pathogenesis and clinical correlations of restless legs syndrome are diverse. Its presentation with the neuropathy clinic can be confusing. The aim of this study is to review nerve conductions of lower extremities in patients with restless legs syndrome and to identify possible differences.
Material and Methods: Distal nerve conductions of the lower extremities were evaluated cross-sectionally in 32 patients diagnosed with restless legs syndrome according to the battery of diagnosis for restless legs syndrome and additional symptoms were questioned. Motor and sensory nerve conductions were assessed with standard protocol. The demographic, clinical features and nerve conductions of restless legs syndrome patients who were on treatment were compared. The results were compared with the healthy control group (n=29).
Results: Neurological examinations of all patients were within normal limits. Both groups were similar in age and gender. Peroneal and sural nerve conduction parameters were not different in both groups (p>0.05). However, the tibial nerve parameters showed a decrease in amplitude and prolongation in distal latency was observed in the patients (p=0.003, p<0.001). We found that the tibial nerve conduction velocity was slower in the patient group (p<0.001).
Conclusion: The results show that in restless legs syndrome patients, tibial nerve conduction parameters may vary according to the control group. Before starting the necessary and appropriate treatment in restless legs syndrome patients, it should be noted that, even if the etiological investigation has been done before, it may be important to renew the tests for an optimal treatment plan.

Proje Numarası

yok

Kaynakça

  • 1. Akyol A, Kiylioglu N, Kadikoylu G, Bolaman AZ, Ozgel N. Iron deficiency anemia and restless legs syndrome: is there an electrophysiological abnormality? Clin Neurol Neurosurg. 2003;106(1):23-7.
  • 2. Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walters AS, Winkelman JW et al. Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria–history, rationale, description, and significance. Sleep Med. 2014;15(8):860-73.
  • 3. Trenkwalder C, Allen R, Högl B, Paulus W, Winkelmann J. Restless legs syndrome associated with major diseases: a systematic review and new concept. Neurology. 2016;86(14):1336-43.
  • 4. Michaud M, Lavigne G, Desautels A, Poirier G, Montplaisir J. Effects of immobility on sensory and motor symptoms of restless legs syndrome. Mov Disord. 2002;17(1):112-5.
  • 5. Trenkwalder C, Bucher SF, Oertel WH. Electrophysiological pattern of involuntary limb movements in the restless legs syndrome. Muscle Nerve. 1996;19(2):155-62.
  • 6. Fulda S, Wetter TC. Emerging drugs for restless legs syndrome. Expert opinion on emerging drugs. 2005;10(3):537-52.
  • 7. Satija P, Ondo WG. Restless legs syndrome: pathophysiology, diagnosis and treatment. CNS Drugs. 2008;22(6):497-518.
  • 8. Ondo W, Jankovic J. Restless legs syndrome: clinicoetiologic correlates. Neurology. 1996;47(6):1435-41.
  • 9. Polydefkis M, Allen R, Hauer P, Earley CJ, Griffin J, McArthur JC. Subclinical sensory neuropathy in late-onset restless legs syndrome. Neurology. 2000;55(8):1115-21.
  • 10. Iannacone S, Ferrini-Strambi L, Zucconi M. Peripheral nerve investigation in restless legs syndrome. J Neurol. 1994;241(Suppl 1):S156.
  • 11. Nineb A, Rosso C, Dumurgier J, Nordine T, Lefaucheur JP, Creange A. Restless legs syndrome is frequently overlooked in patients being evaluated for polyneuropathies. Eur J Neurol. 2007;14(7):788-92.
  • 12. Teive HA, Munhoz RP, Barbosa ER. Professor Karl-Axel Ekbom and restless legs syndrome. Parkinsonism Relat Disord. 2009;15(4):254-7.
  • 13. Montplaisir J, Godbout R, Boghen D, DeChamplain J, Young S, Lapierre G. Familial restless legs with periodic movements in sleep: electrophysiologic, biochemical, and pharmacologic study. Neurology. 1985;35(1):130-4.
  • 14. Gonzalez-Latapi P, Malkani R. Update on restless legs syndrome: from mechanisms to treatment. Curr Neurol Neurosci Rep. 2019;19(8):1-12.
  • 15. Bastia JK, Bhoi SK, Kalita J, Misra UK. Neuropathy in a cohort of restless leg syndrome patients. J Clin Neurosci. 2015;22(8):1314-8.
  • 16. Preston DC, Shapiro BE. Electromyography and neuromuscular disorders e-book: clinical-electrophysiologic correlations. 3th ed. Netherlands. Elsevier Saunders, 2012.
  • 17. Allen RP, Bharmal M, Calloway M. Prevalence and disease burden of primary restless legs syndrome: results of a general population survey in the United States. Mov Disord. 2011;26(1):114-20.
  • 18. Hartmann M, Pfister R, Pfadenhauer K. Restless legs syndrome associated with spinal cord lesions. J Neurol Neurosurg Psychiatry. 1999;66(5):688-9.
  • 19. Freeman AA, Rye DB. The molecular basis of restless legs syndrome. Curr Opin Neurobiol. 2013;23(5):895-900.
  • 20. Pitarokoili K, Fels M, Kerasnoudis A, Tönges L, Gold R, Yoon MS. High‐resolution nerve ultrasound and electrophysiological findings in restless legs syndrome. J Neuroimaging. 2018;28(5):506-14.
  • 21. Rajabally YA, Shah RS. Restless legs syndrome in chronic inflammatory demyelinating polyneuropathy. Muscle Nerve. 2010;42(2):252-6.
  • 22. Hanewinckel R, Drenthen J, van Oijen M, Hofman A, van Doorn PA, Ikram MA. Prevalence of polyneuropathy in the general middle-aged and elderly population. Neurology. 2016;87(18):1892-8.
  • 23. Bastia JK, Bhoi SK, Kalita J, Misra UK. Neuropathy in a cohort of restless leg syndrome patients. J Clin Neurosci. 2015;22(8):1314-8.
  • 24. Anderson JC, Fritz ML, Benson JM, Tracy BL. Nerve decompression and restless legs syndrome: a retrospective analysis. Front Neurol. 2017;6(8):287.
  • 25. Kocabicak E, Terzi M, Akpinar K, Paksoy K, Cebeci I, Iyigun O. Restless leg syndrome and sleep quality in lumbar radiculopathy patients. Behav Neurol. 2014;2014:245358.
  • 26. Becker PM, Novak M. Diagnosis, comorbidities, and management of restless legs syndrome. Curr Med Res Opin. 2014;30(8):1441-60.
  • 27. Sethi KD, Mehta SH. A clinical primer on restless legs syndrome: what we know, and what we don't know. Am J Manag Care. 2012;18(5 Suppl):S83-8.
  • 28. Mastaglia FL. Tibial nerve entrapment in the popliteal fossa. Muscle Nerve. 2000;23(12):1883-6.
  • 29. Neary KC, Chang E. Tarsal tunnel syndrome secondary to accessory musculature: a case report. Foot Ankle Spec. 2019;12(6):549-54.
Toplam 29 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Makaleler
Yazarlar

Hikmet Saçmacı 0000-0003-1480-0562

Mesude Kisli 0000-0002-5212-297X

Proje Numarası yok
Yayımlanma Tarihi 31 Ağustos 2021
Gönderilme Tarihi 26 Ocak 2021
Yayımlandığı Sayı Yıl 2021

Kaynak Göster

APA Saçmacı, H., & Kisli, M. (2021). TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME. The Journal of Kırıkkale University Faculty of Medicine, 23(2), 236-244. https://doi.org/10.24938/kutfd.868709
AMA Saçmacı H, Kisli M. TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME. Kırıkkale Üni Tıp Derg. Ağustos 2021;23(2):236-244. doi:10.24938/kutfd.868709
Chicago Saçmacı, Hikmet, ve Mesude Kisli. “TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME”. The Journal of Kırıkkale University Faculty of Medicine 23, sy. 2 (Ağustos 2021): 236-44. https://doi.org/10.24938/kutfd.868709.
EndNote Saçmacı H, Kisli M (01 Ağustos 2021) TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME. The Journal of Kırıkkale University Faculty of Medicine 23 2 236–244.
IEEE H. Saçmacı ve M. Kisli, “TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME”, Kırıkkale Üni Tıp Derg, c. 23, sy. 2, ss. 236–244, 2021, doi: 10.24938/kutfd.868709.
ISNAD Saçmacı, Hikmet - Kisli, Mesude. “TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME”. The Journal of Kırıkkale University Faculty of Medicine 23/2 (Ağustos 2021), 236-244. https://doi.org/10.24938/kutfd.868709.
JAMA Saçmacı H, Kisli M. TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME. Kırıkkale Üni Tıp Derg. 2021;23:236–244.
MLA Saçmacı, Hikmet ve Mesude Kisli. “TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME”. The Journal of Kırıkkale University Faculty of Medicine, c. 23, sy. 2, 2021, ss. 236-44, doi:10.24938/kutfd.868709.
Vancouver Saçmacı H, Kisli M. TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROME. Kırıkkale Üni Tıp Derg. 2021;23(2):236-44.

Bu Dergi, Kırıkkale Üniversitesi Tıp Fakültesi Yayınıdır.