Allergen Determination with Detection of Serum Specific IgE in Dogs with Atopic Dermatitis from Samsun and Vicinity

Öz

It is aimed to detect allergen determination via serum specific immunoglobulin E (IgE) for the first time in dogs diagnosed as Atopic Dermatitis (AD) from Samsun and vicinity within this present study. Twenty one dogs with different age, breed and gender diagnosed with AD based up on the Favrot’s criteria. Serum samples of the dogs were analyzed by detection of serum specific IgE for determination of 20 different allergens. The effects of gender, age and the feeding routes for those 20 different allergens separately were analyzed. Based up on the grading of the allergens detected in 21 dogs with AD from Samsun and vicinity; results reflects that Dermatophagoides farinae was stated as first degree within a very high seropositivity rate (95%). Moreover, in varying degree of seropositivitiy rates of other allergens were also detected. Females showed statistically (p<0.05) higher positivity rate to the 20^th allergen, Ctenocephalides spp. more than males. Furthermore, we did not found any significant effects of age and feeding routes on the allergens in the dogs with AD (p>0.05). Dogs with AD from Samsun and vicinity had very high serum specific IgE levels against to the house dust and storage mites.

Anahtar Kelimeler

• Allergen,Atopic dermatitis,Dog,Samsun,Specific IgE

Samsun İli ve Çevresindeki Atopik Dermatitisli Köpeklerde Serum Spesifik IgE Tespiti ile Alerjen Tayini

Öz

Bu çalışma ile Samsun ili ve çevresindeki Atopik Dermatitis (AD)’li köpeklerde ilk kez serum spesifik immunoglobin E (IgE) ile alerjen profillerinin belirlenmesi amaçlanmıştır. Değişik ırk, cinsiyet ve yaşlardaki 21 adet köpeğe Favrot Kriterleri ile AD teşhisi konulmuştur. Köpeklere ait serum örnekleri serolojik olarak 20 farklı alerjene spesifik IgE yönünden incelenmiştir. AD’li köpeklerde 20 farklı alerjenin görülme oranlarına cinsiyet, yaş ve beslenme şekillerinin etkisi araştırılmıştır. Samsun ili ve çevresindeki AD’li köpeklerdeki farklı alerjen profilleri arasında en yüksek %95 oranında ev tozu akarı Dermatophagoides farinae seropozitifliği saptanmıştır. Bununla birlikte köpeklerde farklı oranlarda diğer alerjenlere yönelik seropozitiflik saptanmıştır. Dişi köpeklerde erkek köpeklere oranla sadece Ctenocephalides spp. seropozitifliğinin yüksek olduğu istatistiksel olarak tespit edilmiştir (p<0,05). Bununla birlikte AD’li köpeklerde yaş ve beslenme şekillerinin alerjen görülme sıklığına etkisinin olmadığı tespit edilmiştir (p>0,05). Samsun ili ve çevresindeki AD’li köpeklerde ev tozu ile depo akarlarının serum spesifik IgE değerlerinin çok yüksek oranlarda pozitiflik verdiği saptanmıştır. 

Anahtar Kelimeler

• Alerjen,Atopik dermatitis,Köpek,Samsun,Spesifik IgE

Kaynakça

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