Evaluation of Serum Amyloid-A Levels in Clinically Detected Pneumonia in Goats

Öz

In this study, 20 goats between the ages of 0-24 months were used. After clinical, systemic, and hematological examinations, goats were divided into two groups. Clinically diagnosed with pneumonia (n=10) were the study group, whereas healthy goats (n=10) were formed as the control group. Auscultation was performed in the clinical examination. Blood samples from Vena jugularis in the hematological study, White Blood Cell (WBC), Red Blood Cell (RBC), Hemoglobin (Hb), Hematocrit (Hct), Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH); Mean Corpuscular Hemoglobin Concentration (MCHC) concentrations were performed. In blood serum, Total Protein (TP), Albumin (ALB), Serum Amyloid-A (SAA) concentrations were measured. As a result, the values of WBC and SAA are statistically higher in goats with pneumonia compared with the control group. As for RBC, Hb, Hct, MCV, MCH, MCHC, TP, ALB concentrations, no statistical difference was found between the two groups. As a result, we think SAA is the most valuable parameter to evaluate the course of the disease and prognosis along with hematologic, biochemical, and clinical findings in veterinary medicine.

Anahtar Kelimeler

• Pneumonia
• Goat
• Serum Amyloid-A

Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi

Öz

Sunulan çalışmada 0-24 aylık 20 adet keçi kullanıldı. Keçilerin klinik, sistemik ve hematolojik muayeneleri yapıldıktan sonra onarlı iki gruba ayrıldı. Klinik olarak pnömoni teşhisi (n=10 ) konulan keçiler çalışma grubuna, sağlıklı keçiler ise kontrol (n=10 ) grubuna dahil edildi. Klinik muayene sırasında oskültasyon yapıldı. Vena jugularisten alınan kan örneklerinden hematolojik muayenede; Lökosit (WBC), Eritrosit (RBC), Hemoglobin (HGB), Hematokrit (HCT), Eritrosit Hacmi (MCV), Eritrosit Ortalama Hemoglobin Miktarı (MCH), Eritrosit Ortalama Hemoglobin Yoğunluğu (MCHC) konsantrasyonları ölçüldü. Kan örneklerinden elde edilen serumlarda; Total Protein (TP), Albumin (ALB) ve Serum Amiloid-A (SAA) konsantrasyonu ölçüldü. Yapılan çalışma sonucunda pnömonili keçilerde WBC ve SAA konsantrasyonları, kontrol grubuna göre istatistiksel açıdan yüksek tespit edildi. RBC, HGB, HCT, MCV, MCH, MCHC, TP, ALB konsantrasyonlarında gruplar arasında bir fark tespit edilmedi. Sunulan çalışma sonuçları dikkate alındığında SAA’nın veteriner hekimlik alanında, hematolojik, biyokimyasal, ve klinik bulgularla beraber hastalığın prognozunun değerlendirilmesinde önemli bir parametre olduğunu düşünmekteyiz.

Anahtar Kelimeler

• Pnömoni
• Keçi
• Serum Amiloid-A

Kaynakça

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