Neonatal İshalli Buzağılarda 25 (OH) D3 Konsantrasyonlarının Araştırılması

Yıl 2019, Cilt: 12 Sayı: 3, 268 - 276, 30.09.2019

Hasan Erdoğan Tahir Özalp

https://doi.org/10.30607/kvj.532206

Öz

Bu araştırma ile neonatal dönemde ishal semptomu gösteren
buzağıların plazma vitamin D₃ ve fibrinojen konsantrasyonları
arasındaki ilişkinin belirlenmesi amaçlandı. Bu kapsamda neonatal ishalli
(n=100) ve sağlıklı (n=20) buzağılar araştırmaya dahil edildi. İshalli
buzağılar kendi içerisinde mono enfekte ve ko enfeksiyon gruplarına göre iki
ana gruba, mono-enfekte buzağılar kendi içerisinde E. coli,
Rotavirus, Coronavirus, Cryptosporidium
sp., ve Giardia sp., ko-enfekte
buzağılar ise Rotavirus + Cryptosporidium
sp. ve E. coli + Cryptosporidium sp. olacak şekilde alt
gruplara ayrıldı. Buzağıların %6’sının E. coli, %19’u Cryptosporidium sp.,
%13’ü Rotavirus, %6’sı Coronovirus, %6’sı Giardia ile mono-enfekte, ko-enfekte
buzağıların ise %11’i E. coli + Cryptosporidium sp., ve %22’sinin
Rotavirüs + Cryptosporidium sp., ile
enfekte ve %17’nin sağlıklı olduğu belirlendi. Sağlıklı buzağılara göre mono
enfekte ve ko-enfekte buzağıların fibrinojen konsantrasyonlarının anlamlı
düzeyde yüksek olduğu buna karşın 25 (OH) D₃ seviyelerinin ise her iki grupta sağlıklı
buzağılara göre anlamlı derecede düşük olduğu belirlendi. İshalli buzağılarda
fibrinojen ve 25 (OH) D₃ konsantrasyonları arasında (r= - 403, p<0,05) negatif korelasyon bulunduğu belirlendi. Sonuç olarak 25
(OH) D₃
konsantrasyonlarının ishalli buzağılarda enfeksiyonun varlığı ve şiddetine
bağlı olarak azaldığı tespit edildi.

Anahtar Kelimeler

Akut faz protein, Buzağı, Fibrinojen, İshal, Vitamin D3

Evaluation of 25 (OH) D3 Concentrations in Neonatal Calves with Diarrhea

Öz

In the present study
the aim was to determine the relationship between plasma vitamin D3 and
fibrinogen concentrations of calves with diarrhea. İn this context, calves
neonatal diarrhea (n = 100) and healthy (n = 20) ones were enrolled. Diarrheic
calves were enrolled into two intra-groups of mono and co-infected, then
mono-infected calves and co-infected calves were divided into subgroups
according to E. coli, Rotavirus, Coronavirus, Cryptosporidium sp.,
and Giardia sp., and Rotavirus + Cryptosporidium sp. and E. Coli +
Cryptosporidium sp. It was determined that 6% of the calves were infected with
and E.coli, 13% Rotavirus, 6% Coronavirus, 6% Giardia in mono-infected ones and
11% E.coli + Cryptosporidium sp., and 22% Rotavirus + Cryptosporidium sp., with
co-infection and 17% healthy. According to healthy calves, mono-infected and
co-infected calves had significantly higher fibrinogen concentrations, whereas
25 (OH) D3 levels were significantly lower in both groups than healthy calves.
There was a negative correlation between fibrinogen and 25 (OH) D3
concentrations (r = - 403, p <0.05) in calves with diarrhea. As a result, 25
(OH) D3 concentrations decreased in diarrhea calves due to the presence and
severity of the infection. 

Anahtar Kelimeler

vitamin D3, Calf, fibrinogen, diarrhea

Kaynakça

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