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Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi

Yıl 2021, Cilt 14, Sayı 4, 430 - 435, 31.12.2021
https://doi.org/10.30607/kvj.898478

Öz

Sunulan çalışmada 0-24 aylık 20 adet keçi kullanıldı. Keçilerin klinik, sistemik ve hematolojik muayeneleri yapıldıktan sonra onarlı iki gruba ayrıldı. Klinik olarak pnömoni teşhisi (n=10 ) konulan keçiler çalışma grubuna, sağlıklı keçiler ise kontrol (n=10 ) grubuna dahil edildi. Klinik muayene sırasında oskültasyon yapıldı. Vena jugularisten alınan kan örneklerinden hematolojik muayenede; Lökosit (WBC), Eritrosit (RBC), Hemoglobin (HGB), Hematokrit (HCT), Eritrosit Hacmi (MCV), Eritrosit Ortalama Hemoglobin Miktarı (MCH), Eritrosit Ortalama Hemoglobin Yoğunluğu (MCHC) konsantrasyonları ölçüldü. Kan örneklerinden elde edilen serumlarda; Total Protein (TP), Albumin (ALB) ve Serum Amiloid-A (SAA) konsantrasyonu ölçüldü. Yapılan çalışma sonucunda pnömonili keçilerde WBC ve SAA konsantrasyonları, kontrol grubuna göre istatistiksel açıdan yüksek tespit edildi. RBC, HGB, HCT, MCV, MCH, MCHC, TP, ALB konsantrasyonlarında gruplar arasında bir fark tespit edilmedi. Sunulan çalışma sonuçları dikkate alındığında SAA’nın veteriner hekimlik alanında, hematolojik, biyokimyasal, ve klinik bulgularla beraber hastalığın prognozunun değerlendirilmesinde önemli bir parametre olduğunu düşünmekteyiz.

Kaynakça

  • Alsemgeest SPM, Kalsbeek HC, Wensing TH, Koeman JP, Ederen AM, Gruys E. Concentrations of serum amyloid A (SAA) and Haptoglobin (Hp) as parameters of inflammatory disease in cattle. Veterinary Quarterly. 1994; 16(1): 21-23.
  • Balamurugan R, Durgalakshmi R, Sheeba A. Effect of gender on certain serum biochemical parameters of Desi goats in cauvery delta region. J Anim Nutr and Physiol. 2015; 1:34-36.
  • Bolanos-Garcia VM, Miguel RN. On the structure and function of apolipoproteins: More than a family of lipid-binding proteins. Prog. Biophys. Mol. Biol. 2002; 883:47–68.
  • Boudreaux CM. A novel strategy ofcontrolling bovine pneumonic pasteurellosis: Transfecting the upper respiratory tractof cattle with a gene coding for the antimicrobial peptide cecropin B. M. Sc. Thesis,Louisiana State University,USA. 2004.
  • Cecilıani F, Ceron JJ, Eckersall PD, Sauerweın H. Acute phase proteins in ruminants. 2012; 1-25.
  • Cray C, Zaias J, Altman NH. Acute phase response in animals: A review. Comp. Med. 2009; 59:517–526.
  • Czopowicz M, Jordanow OS, Mickiewicz M, Moroz A, Witkowski L, Markowska DI, Reczyńska D, Bagnicka E, Kaba J. Agreement between commercial assays for haptoglobin and serum amyloid A in goats. Acta Vet Scand. 2017; 59:65.
  • Daniel, Joseph A, et al. "Evaluation of the prevalence and onset of lung lesions and their impact on growth of lambs." American Journal of Veterinary Research 67.5 2006; 890-894.
  • Daramola JO, Adeloye AA, Fatoba TA, Soladoye AO. Haematological and biochemical parameters of West African Dwarf goats. Livest Res Rural Dev. 2005; 17:(95).
  • Davies RL, Arkinsaw S, Selander RK. Evolutionary genetics of Pasteurella haemolytica isolates recovered from cattle and sheep. Infection and Immunity. 1997; 65(9): 3585-3593.
  • Eckersall PD, Bell R. Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine. The Veterinary Journal. 2010; 185: 23-27.
  • Ezeasor CK, Emikpe BO, Anosa VO. Haematological changes associated with intranasal and parenteral routes of vaccination against Peste des petits ruminants in West African dwarf goats. Comp Clin Pathol. 2015; 24:189–192.
  • Fisher AD, Knight TW, Cosgrove GP, Death AF. Effects of surgical or banding castration on stres responses and behaviour of bulls. Aust. Vet. J. 2001; 79:279-84.
  • Gökçe H, Bozukluhan K. Çiftlik Hayvanlarında Önemli Akut Faz Proteinleri ve Bunların Veteriner Hekimlik Alanındaki Kullanımı, Dicle Üniv. Vet. Fak. Derg. 2009; 1(1): 1- 14. Gruys E, Obwolo MJ, Toussaınt M. Diagnostic significance of the major acute phase proteins in veterinary clinical chemistry: A Rev Vet Bull. 1994; 64:1009-1018.
  • Heegard PMH, Godson DL, Toussaınt MJM. The acute phase response of haptoglobin and Serum Amyloid A in cattle undergoing experimental infection with bovine respiratory syncytial virus. Vet Immunol Immunopathol. 2000; 77:151-159.
  • Höfner MC, Fosbery MW, Eckersall PD, Donaldson AL. Haptoglobin response of cattle infected with foot-mouth disease virus. Res. Vet. Sci. 1994; 57:125-128.
  • İriadam M. Kilis keçilerine ait bazı hematolojik ve biyokimyasal parametreler Ankara Üniv Vet Fak Derg. 2004; 51:83-85.
  • Jarikre, TA, Emikpe BO, Ohore OG, Akinremi TA, Akpavie SO. Bronchoalveolar Lavage Fluid Cellular and Haematological Changes in Different Types of Caprine Pneumonia Niger. J. Physiol. Sci. 2016; 31:031-036
  • Jensen LE, Whitehead AS. Regulation of serum amyloid A protein expression during the acute-phase response. Biochem. J. 1998; 334:489–503.
  • Maina S, Gitao C, Gathumbi P. Hematological, serological and virological findings in sheep and goats experimentally infected with lineage III peste des petits ruminants virus isolates in Kenya. Journal of Experimental Biology and Agricultural Sciences. 2015; 3:81–88. Merck Manual. Hematologic Reference Ranges. http://www.merckmanuals.com/vet/appendixes/reference_guides/hematologic_reference_ranges.html . 25.08.2020.
  • Mohamed RA, Abdelsalam EB. A Revıew On Pneumonıc Pasteurellosıs (Respıratory Mannheımıosıs) Wıth Emphasıs On Pathogenesıs, Vırulence Mechanısms And Predısposıng FactorsBulgarian Journal of Veterinary Medicine. 2008; 11(3): 139−160.
  • Murata H, Shimada N, Yoshioka M. Current research on acute phase proteins in veterinary diagnosis an overview. Vet. J. 2004; 168: 28–40.
  • Odhah MN, Jesse FFA, Lawan A, Idris UH, Marza AD, Mahmood ZKA, Yusuf, Arsalanh M, Wahid AH. Mohd-Azmi ML, Zamri-Saad M. Responses of haptoglobin and serum amyloid A in goats inoculated intradermally with C. Pseu dotuberculosis and mycolic acid extract immunogen. Microbial Pathogenesis. 2018; 117:243–246.
  • Omidi A, Nik HA, Nazifi S. Biochemical Reference Values For Healthy Captive Persian Wild Goat (Capra Aegagrus). Comp Clin Pathol. 2018; 27:483-491.
  • Petersen HH, Neilsen JP, Heegard PMH. Application of acute phase protein measurements in veterinary clinical chemistry. Veterinary Research. 2004; 353:1-25, 163-187.
  • Piccione G, Casella S, Pennisi P, Giannetto C, Costa A, Caola G. Monitoring of physiological and blood parameters during perinatal and neonatal period in calves. Arq. Bras. Med. Vet. Zootec. 2010; 62(1):1-12.
  • Rastog SK, Singh SP. Normal hemogram and blood analytes of mountain Gaddi goats. Indian J Anim Sei. 1990; 60:1338-1339.
  • Skınner, JG, Brown, RAL, Roberts, L. Bovine haptoglobin response in clinically defined field conditions. Vet Rec. 1991; 128:147-149.
  • Turgut K. Veteriner Klinik Laboratuvar Teşhis. Bahçıvanlar Basımsanayi, Konya, 2000; ss 489-505.

Evaluation of Serum Amyloid-A Levels in Clinically Detected Pneumonia in Goats

Yıl 2021, Cilt 14, Sayı 4, 430 - 435, 31.12.2021
https://doi.org/10.30607/kvj.898478

Öz

In this study, 20 goats between the ages of 0-24 months were used. After clinical, systemic, and hematological examinations, goats were divided into two groups. Clinically diagnosed with pneumonia (n=10) were the study group, whereas healthy goats (n=10) were formed as the control group. Auscultation was performed in the clinical examination. Blood samples from Vena jugularis in the hematological study, White Blood Cell (WBC), Red Blood Cell (RBC), Hemoglobin (Hb), Hematocrit (Hct), Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH); Mean Corpuscular Hemoglobin Concentration (MCHC) concentrations were performed. In blood serum, Total Protein (TP), Albumin (ALB), Serum Amyloid-A (SAA) concentrations were measured. As a result, the values of WBC and SAA are statistically higher in goats with pneumonia compared with the control group. As for RBC, Hb, Hct, MCV, MCH, MCHC, TP, ALB concentrations, no statistical difference was found between the two groups. As a result, we think SAA is the most valuable parameter to evaluate the course of the disease and prognosis along with hematologic, biochemical, and clinical findings in veterinary medicine.

Kaynakça

  • Alsemgeest SPM, Kalsbeek HC, Wensing TH, Koeman JP, Ederen AM, Gruys E. Concentrations of serum amyloid A (SAA) and Haptoglobin (Hp) as parameters of inflammatory disease in cattle. Veterinary Quarterly. 1994; 16(1): 21-23.
  • Balamurugan R, Durgalakshmi R, Sheeba A. Effect of gender on certain serum biochemical parameters of Desi goats in cauvery delta region. J Anim Nutr and Physiol. 2015; 1:34-36.
  • Bolanos-Garcia VM, Miguel RN. On the structure and function of apolipoproteins: More than a family of lipid-binding proteins. Prog. Biophys. Mol. Biol. 2002; 883:47–68.
  • Boudreaux CM. A novel strategy ofcontrolling bovine pneumonic pasteurellosis: Transfecting the upper respiratory tractof cattle with a gene coding for the antimicrobial peptide cecropin B. M. Sc. Thesis,Louisiana State University,USA. 2004.
  • Cecilıani F, Ceron JJ, Eckersall PD, Sauerweın H. Acute phase proteins in ruminants. 2012; 1-25.
  • Cray C, Zaias J, Altman NH. Acute phase response in animals: A review. Comp. Med. 2009; 59:517–526.
  • Czopowicz M, Jordanow OS, Mickiewicz M, Moroz A, Witkowski L, Markowska DI, Reczyńska D, Bagnicka E, Kaba J. Agreement between commercial assays for haptoglobin and serum amyloid A in goats. Acta Vet Scand. 2017; 59:65.
  • Daniel, Joseph A, et al. "Evaluation of the prevalence and onset of lung lesions and their impact on growth of lambs." American Journal of Veterinary Research 67.5 2006; 890-894.
  • Daramola JO, Adeloye AA, Fatoba TA, Soladoye AO. Haematological and biochemical parameters of West African Dwarf goats. Livest Res Rural Dev. 2005; 17:(95).
  • Davies RL, Arkinsaw S, Selander RK. Evolutionary genetics of Pasteurella haemolytica isolates recovered from cattle and sheep. Infection and Immunity. 1997; 65(9): 3585-3593.
  • Eckersall PD, Bell R. Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine. The Veterinary Journal. 2010; 185: 23-27.
  • Ezeasor CK, Emikpe BO, Anosa VO. Haematological changes associated with intranasal and parenteral routes of vaccination against Peste des petits ruminants in West African dwarf goats. Comp Clin Pathol. 2015; 24:189–192.
  • Fisher AD, Knight TW, Cosgrove GP, Death AF. Effects of surgical or banding castration on stres responses and behaviour of bulls. Aust. Vet. J. 2001; 79:279-84.
  • Gökçe H, Bozukluhan K. Çiftlik Hayvanlarında Önemli Akut Faz Proteinleri ve Bunların Veteriner Hekimlik Alanındaki Kullanımı, Dicle Üniv. Vet. Fak. Derg. 2009; 1(1): 1- 14. Gruys E, Obwolo MJ, Toussaınt M. Diagnostic significance of the major acute phase proteins in veterinary clinical chemistry: A Rev Vet Bull. 1994; 64:1009-1018.
  • Heegard PMH, Godson DL, Toussaınt MJM. The acute phase response of haptoglobin and Serum Amyloid A in cattle undergoing experimental infection with bovine respiratory syncytial virus. Vet Immunol Immunopathol. 2000; 77:151-159.
  • Höfner MC, Fosbery MW, Eckersall PD, Donaldson AL. Haptoglobin response of cattle infected with foot-mouth disease virus. Res. Vet. Sci. 1994; 57:125-128.
  • İriadam M. Kilis keçilerine ait bazı hematolojik ve biyokimyasal parametreler Ankara Üniv Vet Fak Derg. 2004; 51:83-85.
  • Jarikre, TA, Emikpe BO, Ohore OG, Akinremi TA, Akpavie SO. Bronchoalveolar Lavage Fluid Cellular and Haematological Changes in Different Types of Caprine Pneumonia Niger. J. Physiol. Sci. 2016; 31:031-036
  • Jensen LE, Whitehead AS. Regulation of serum amyloid A protein expression during the acute-phase response. Biochem. J. 1998; 334:489–503.
  • Maina S, Gitao C, Gathumbi P. Hematological, serological and virological findings in sheep and goats experimentally infected with lineage III peste des petits ruminants virus isolates in Kenya. Journal of Experimental Biology and Agricultural Sciences. 2015; 3:81–88. Merck Manual. Hematologic Reference Ranges. http://www.merckmanuals.com/vet/appendixes/reference_guides/hematologic_reference_ranges.html . 25.08.2020.
  • Mohamed RA, Abdelsalam EB. A Revıew On Pneumonıc Pasteurellosıs (Respıratory Mannheımıosıs) Wıth Emphasıs On Pathogenesıs, Vırulence Mechanısms And Predısposıng FactorsBulgarian Journal of Veterinary Medicine. 2008; 11(3): 139−160.
  • Murata H, Shimada N, Yoshioka M. Current research on acute phase proteins in veterinary diagnosis an overview. Vet. J. 2004; 168: 28–40.
  • Odhah MN, Jesse FFA, Lawan A, Idris UH, Marza AD, Mahmood ZKA, Yusuf, Arsalanh M, Wahid AH. Mohd-Azmi ML, Zamri-Saad M. Responses of haptoglobin and serum amyloid A in goats inoculated intradermally with C. Pseu dotuberculosis and mycolic acid extract immunogen. Microbial Pathogenesis. 2018; 117:243–246.
  • Omidi A, Nik HA, Nazifi S. Biochemical Reference Values For Healthy Captive Persian Wild Goat (Capra Aegagrus). Comp Clin Pathol. 2018; 27:483-491.
  • Petersen HH, Neilsen JP, Heegard PMH. Application of acute phase protein measurements in veterinary clinical chemistry. Veterinary Research. 2004; 353:1-25, 163-187.
  • Piccione G, Casella S, Pennisi P, Giannetto C, Costa A, Caola G. Monitoring of physiological and blood parameters during perinatal and neonatal period in calves. Arq. Bras. Med. Vet. Zootec. 2010; 62(1):1-12.
  • Rastog SK, Singh SP. Normal hemogram and blood analytes of mountain Gaddi goats. Indian J Anim Sei. 1990; 60:1338-1339.
  • Skınner, JG, Brown, RAL, Roberts, L. Bovine haptoglobin response in clinically defined field conditions. Vet Rec. 1991; 128:147-149.
  • Turgut K. Veteriner Klinik Laboratuvar Teşhis. Bahçıvanlar Basımsanayi, Konya, 2000; ss 489-505.

Ayrıntılar

Birincil Dil Türkçe
Konular Veteriner Hekimlik
Bölüm ARAŞTIRMA MAKALESİ
Yazarlar

Kadir DEMİRBAŞ Bu kişi benim
Ardahan İl Tarım ve Orman Müdürlüğü, 75000, Ardahan, Türkiye
0000-0002-8715-6061
Türkiye


Mustafa KABU (Sorumlu Yazar)
AFYON KOCATEPE ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ
0000-0003-0554-7278
Türkiye

Destekleyen Kurum AKÜ BAP
Proje Numarası 16. SAĞ.BİL.22
Yayımlanma Tarihi 31 Aralık 2021
Yayınlandığı Sayı Yıl 2021, Cilt 14, Sayı 4

Kaynak Göster

Bibtex @araştırma makalesi { kvj898478, journal = {Kocatepe Veterinary Journal}, issn = {1308-1594}, eissn = {2147-6853}, address = {}, publisher = {Afyon Kocatepe Üniversitesi}, year = {2021}, volume = {14}, number = {4}, pages = {430 - 435}, doi = {10.30607/kvj.898478}, title = {Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi}, key = {cite}, author = {Demirbaş, Kadir and Kabu, Mustafa} }
APA Demirbaş, K. & Kabu, M. (2021). Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi . Kocatepe Veterinary Journal , 14 (4) , 430-435 . DOI: 10.30607/kvj.898478
MLA Demirbaş, K. , Kabu, M. "Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi" . Kocatepe Veterinary Journal 14 (2021 ): 430-435 <https://dergipark.org.tr/tr/pub/kvj/issue/64946/898478>
Chicago Demirbaş, K. , Kabu, M. "Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi". Kocatepe Veterinary Journal 14 (2021 ): 430-435
RIS TY - JOUR T1 - Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi AU - Kadir Demirbaş , Mustafa Kabu Y1 - 2021 PY - 2021 N1 - doi: 10.30607/kvj.898478 DO - 10.30607/kvj.898478 T2 - Kocatepe Veterinary Journal JF - Journal JO - JOR SP - 430 EP - 435 VL - 14 IS - 4 SN - 1308-1594-2147-6853 M3 - doi: 10.30607/kvj.898478 UR - https://doi.org/10.30607/kvj.898478 Y2 - 2021 ER -
EndNote %0 Kocatepe Veteriner Dergisi Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi %A Kadir Demirbaş , Mustafa Kabu %T Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi %D 2021 %J Kocatepe Veterinary Journal %P 1308-1594-2147-6853 %V 14 %N 4 %R doi: 10.30607/kvj.898478 %U 10.30607/kvj.898478
ISNAD Demirbaş, Kadir , Kabu, Mustafa . "Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi". Kocatepe Veterinary Journal 14 / 4 (Aralık 2021): 430-435 . https://doi.org/10.30607/kvj.898478
AMA Demirbaş K. , Kabu M. Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi. Kocatepe Veterinary Journal. 2021; 14(4): 430-435.
Vancouver Demirbaş K. , Kabu M. Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi. Kocatepe Veterinary Journal. 2021; 14(4): 430-435.
IEEE K. Demirbaş ve M. Kabu , "Klinik Olarak Pnömoni Tespit Edilen Keçilerde Serum Amiloid-A Düzeylerinin Değerlendirilmesi", Kocatepe Veterinary Journal, c. 14, sayı. 4, ss. 430-435, Ara. 2021, doi:10.30607/kvj.898478

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