Clinical Evaluation of Cases of Pandemic H1N1 Influenza in Sanliurfa Province in Epidemic Period

Yıl 2018, Cilt: 2 Sayı: 1, 14 - 19, 12.03.2018

Halil Kazanasmaz , Süleyman Geter Abdullah Solmaz , Şakir Genç , Hüseyin Gümüş

https://doi.org/10.30565/medalanya.368195

Cited By: 1

Öz

Aim: In this study, we aimed to share our experience with
75 patients admitted to the hospital who adhered to the definition of influenza-like
illness.

Patients and
Methods: Pandemic 2009 influenza positive
and negative cases with RNA (ribonucleic acid) detected by PCR (polymerase
chain reaction) method were compared in terms of age, gender and underlying
disease relationships, laboratory and radiological imaging results, hospital
stay and intensive care unit stay and discharge patterns.

Results: There was no significant difference in sex
distribution, age and  chest x-ray
findings between the two groups. When the CRP(C-reactive protein) and platelet
levels of the groups were compared between the groups, there was a meaningful
difference between them, but there was no significant difference in terms of
white cell, hemoglobin, neutrophil and lymphocyte counts. The mean CRP level in
the H1N1 positive group was significantly higher than the H1N1 negative group.
In the H1N1 positive group, the mean platelet amount was significantly lower
than in the H1N1 negative group.                                         

Conclusion: Clinical follow-up of pandemic H1N1 influenza cases
is very important. Pandemic influenza (H1N1) was thought to be fatal in some
cases in the underlying chronic illness.

Anahtar Kelimeler

H1N1, influenza, oseltamivir, PCR, pneumonia

Epidemik Dönemde Şanlıurfa İli Pandemik H1N1 İnfluenza Olgularının Klinik Değerlendirmesi

Öz

Amaç: Bu çalışmada; influenza benzeri hastalık
tanımına uyan ve hastaneye yatırılan 75 olgu ile ilgili deneyimlerimizin paylaşılması
amaçlandı.

Hastalar ve Yöntem: PZR (polimeraz zincir reaksiyonu)
yöntemiyle RNA (ribonükleik asit) tespit edilmiş pandemik 2009 influenza
pozitif olgular ile negatif olguların yaş, cinsiyet ve altta yatan hastalık
ilişkileri, laboratuvar ve radyolojik görüntüleme sonuçları, hastanede ve yoğun
bakımda yatış süreleri ve taburculuk şekilleri karşılaştırıldı.

Bulgular: Her iki grup arasında cinsiyet dağılımı,
yaş ve akciğer grafisi bulguları açısından anlamlı bir fark görülmedi. Gruplar
arası laboratuvar parametrelerinden CRP(C-reaktif protein) ve platelet
düzeyleri karşılaştırıldığında arada anlamlı fark bulunurken beyaz küre,
hemoglobin, nötrofil ve lenfosit sayıları açısından arada anlamlı fark
bulunmadı. H1N1 pozitif grupta ortalama CRP miktarı H1N1 negatif gruba göre
anlamlı olarak daha yüksek düzeyde bulundu. H1N1 pozitif grupta ortalama
platelet miktarı anlamlı olarak H1N1 negatif gruba göre daha düşük bulundu.                                                                                                                                                                                                                            

Sonuç: Pandemik H1N1 influenza olgularının klinik
takipleri oldukça önemlidir. Altta yatan kronik hastalık zemininde pandemik
influenzanın (H1N1)  bazı vakalarda fatal
seyredebileceği düşünüldü.

Anahtar Kelimeler

H1N1, influenza, oseltamivir, PZR, pnömoni

Kaynakça

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