Seroprevalence of Maedi-Visna Infection in Sheep in the Central Black Sea Region of Türkiye
Yıl 2024,
Cilt: 14 Sayı: 1, 40 - 47, 28.06.2024
Hanne Nur Kuruçay
,
Bahadir Müftüoğlu
,
Seda Gözel
,
Ahmed Eısa Elhag
,
Cüneyt Tamer
,
Semra Gümüşova
,
Harun Albayrak
Öz
Maedi-Visna is a slowly progressive infection of sheep that affects the respiratory and nervous systems and causes significant yield losses worldwide. This study was conducted to assess the seroprevalence of Maedi-Visna infection in sheep across several provinces in the Central Black Sea region of Türkiye, namely Samsun, Sinop, Ordu, Giresun, Amasya and Tokat. A total of 476 sheep serum samples were collected for further analysis. The presence of antibodies in the sera was determined by Ab ELISA. As a result of the study, 263 (55.25%) blood serum samples were positive for the presence of MVV antibodies. Seropositivity rates by province were as follows: Samsun 45%, Sinop 80%, Ordu 58.75%, Giresun 35%, Amasya 38.75%, Tokat 75%. Notably, our findings suggest a significantly high seroprevalence of Maedi-Visna infection in this region compared to other studies conducted in different parts of Türkiye This information is pivotal for understanding the extent of the infection in the sheep population of the Central Black Sea region and can contribute to the development of strategies for disease management and control.
Etik Beyan
Sunduğum makalenin etik kurallara uygun bir çalışma olduğunu, herhangi bir başka dergide yayımlanmak üzere verilmediğini, daha önce yayımlanmadığını, eğer tümüyle ya da bir bölümü yayınlandı ise yukarda adı geçen dergide yayınlanabilmesi için gerekli her türlü iznin alındığını ve orijinal telif hakkı formu ile birlikte Manas Journal of Agriculture Veterinary and Life Sciences’a gönderildiğini garanti ederim.
Kaynakça
- Akkan, H.A., Karaca, M., Tütüncü, M., Keles, I., Ilhan, F., Cetin, Y., & Tasal, I. (2009). Investigation of the
seroprevalance of maedi-visna in the region of Van using Elisa and histopathological findings. Journal of
Animal and Veterinary Advances, 8(8), 1495-1498
- Albayrak, H., Yazici, Z., Okur-Gumusova, S., & Ozan, E. (2012). Maedi-visna virus infection in Karayaka and
Amasya Herik breed sheep from provinces in northern Turkey. Tropical Animal Health and Production, 44, 939-
941. DOI: 10.1007/s11250-011-9996-9
- Alibaşoglu, M., & Arda, M. (1975). Koyun pulmoner adenomatozisi'nin Türkiye'de durumu ile patolojisi ve
etiyolojisinin araştırılması. Tübitak Vhag Yayınları, 274.
- Arık, C., Acar, A., & Gür, S. (2015). Afyonkarahisar İli ve Çevresinde Maedi-Visna Virüs Enfeksiyonunun Klinik ve
Serolojik Olarak Araştırılması. Kocatepe Veterinary Journal, 8(1): 39-44. DOI: 10.5578/kvj.8985
- Arslan, S., Savsunlu, Z., Vural, T., Arslan, H., Yüksel, M., Şelli, M. Ş., & Çabalar, M. (2012). Şanlıurfa ilindeki koyunlarda
maedi-visna enfeksiyonunun varlığı ve yaygınlığının araştırılması. 10. Ulusal Veteriner Hekimleri Mikrobiyoloji
Kongresi, 24(27), 374.
- Azkur, A. K., Gazyagci, S., & Aslan, M. E. (2011). Serological and epidemiological investigation of bluetongue,
Maedi-Visna and caprine arthritis-encephalitis viruses in small ruminant in Kirikkale District in Turkey. Kafkas
Universitesi Veteriner Fakultesi Dergisi 17 (5): 803-808. DOI:10.9775/kvfd.2011.4492.
- Blacklaws, B.A. (2012). Small ruminant lentiviruses: Immunopathogenesis of visna-maedi and caprine arthritis
and encephalitis virus. Comparative İmmunology, Microbiology and Infectious Diseases, 35(3), 259-269. DOI:
10.1016/j.cimid.2011.12.003
- Blacklaws, B.A., Berriatua, E., Torsteinsdottir, S., Watt, N.J., Andres, D. De., Klein, D., & Harkiss, G.D. (2004).
Transmission of small ruminant lentiviruses. Veterinary Microbiology., 101 (2004), pp. 199-208,
10.1016/j.vetmic.2004.04.006
- De Boer, G.F., & Houwers, D.J. (1979). Epizootiology of maedi/visna in sheep. In Aspects of Slow and Persistent
Virus Infections: Proceedings of the European Workshop sponsored by the Commission of the European
Communities on the advice of the Committee on Medical and Public Health Research, held in London (UK),
April 5–6, 1979 (pp. 198-221). Dordrecht: Springer Netherlands.
- Broughton-Neiswanger, L. E., White, S. N., Knowles, D. P., Mousel, M. R., Lewis, G. S., Herndon, D. R., & Herrmann-
Hoesing, L. M. (2010). Non-maternal transmission is the major mode of ovine lentivirus transmission in a ewe
flock: A molecular epidemiology study. Infection, Genetics and Evolution, 10(7), 998-1007. DOI:
10.1016/j.meegid.2010.06.007
- Burgu, I., Toker, A., Akca, Y., Alkan, F., Yazıcı, Z., & Özkul, A. 1990. Serological studies on visna maedi virus infection
of sheep in Turkey. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 37 (3) : 538-553.
https://doi.org/10.1501/Vetfak_0000001331
- Cheevers, W. P., Knowles, D. P., McGuire, T. C., Baszler, T. V., & Hullinger, G. A. (1994). Caprine arthritis-encephalitis
lentivirus (CAEV) challenge of goats immunized with recombinant vaccinia virus expressing CAEV surface and
transmembrane envelope glycoproteins. Veterinary Immunology and Immunopathology, 42(3-4), 237-251.
DOI: 10.1016/0165-2427(94)90070-1
- Christodoulopoulos, G. (2006). Maedi–Visna: Clinical review and short reference on the disease status in
Mediterranean countries. Small Ruminant Research, 62(1-2), 47-53. DOI: 10.1016/j.smallrumres.2005.07.046
- Çimtay, İ., Keskin, O., & Şahin, T. (2004). Şanlıurfa yöresinde koyun ve keçilerde bazı lentivirus enfeksiyonlarının
araştırılması. Journal of Research in Veterinary Medicine, 23, 1-2-3: 33-38.
- Dawson, M. (1980). Maedi/visna: a review. The Veterinary Record, 106(10), 212-216. DOI: 10.1136/vr.106.10.212
- De Boer, G.F.(1975). Zwoegerziekte virus, the causative agent for progressive interstitial pneumonia (maedi)
and meningo-leucoencephalitis (visna) in sheep. Research in Veterinary Science. 18, 15–25.
- Gezer, T., Akyüz, E., & Gökçe, G. (2021). Investigation of Seroprevalence of Maedi-Visna Infection in some sheep
flocks in Kars province, Turkey. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 14(1), 48-51. DOI:
https://doi.org/10.47027/duvetfd.881430
- Girgin, H., Aydın, N., Yonguç, A. D., Aksoy, E., & Çorak, R. (1987). Ve şimdi koyunların viral maedi-visna'sı Türkiye'de.
Etlik Veteriner Mikrobiyoloji Dergisi, 6(1), 9-22.
- Glaria, I., Reina, R., Ramirez, H., De Andres, X., Crespo, H., Jauregui, P., Salazar, E., Luján, L., Pérez, M.M., Benavides, J.,
Pérez, V., Polledo, L., García-Marín, J.F., Riezu, J.I., Borrás, F., Amorena, B., & De Andrés, D. (2012). Visna/Maedi
virus genetic characterization and serological diagnosis of infection in sheep from a neurologicaloutbreak.
Veterinary microbiology, 155(2-4), 137-146. https://doi.org/10.1016/j.vetmic.2011.08.027
- Gomez-Lucia, E., Barquero, N., & Domenech, A. (2018). Maedi-Visna virus: current perspectives. Veterinary
Medicine: Research and Reports, 11-21. DOI: 10.2147/VMRR.S136705
- González, B., Reina, R., García, I., Andrés, S., Glaria, I., Alzueta, M., Mora, M.I., Jugo, B.M., Arrieta-Aguirre,I., de la
Lastra,J.M.P., Rodríguez, D.,Rodríguez, J.R., Esteban, M., Grilló, M.J., Barbara, A.B., Harkiss, G.D., Chebloune, Y.,
Luján, L., de Andrés D., & Amorena, B. (2005). Mucosal immunization of sheep with a Maedi-Visna virus (MVV)
env DNA vaccin protects against early MVV productive infection. Vaccine, 23(34), 4342-4352. DOI:
10.1016/j.vaccine.2005.03.032
- Gürçay, M., & Parmaksız, A. (2013). An investigation of Visna-Maedi virus infection in Şanlıurfa Province,
Southeast Anatolia, Turkey. Adana Veteriner Kontrol Enstitüsü Müdürlüğü Dergisi, 3(1), 46-50.
- Heaton, M. P., Kalbfleisch, T. S., Petrik, D. T., Simpson, B., Kijas, J. W., Clawson, M. L., Carol, G.C.Mc., Gregory, P.H.,
Kreg, A.L., & International Sheep Genomics Consortium. (2013). Genetic testing for TMEM154 mutations
associated with lentivirus susceptibility in sheep. PloS One, 8(2), e55490.
- International Committee on Taxonomy of Viruses: ICTV.2023 https://ictv.global/taxonomy.
- Kaba, J., Czopowicz, M., Ganter, M., Nowicki, M., Witkowski, L., Nowicka, D., & Szaluś-Jordanow, O. (2013). Keçi
sürülerinde küçük ruminant lentivirüslere karşı seropozitiflik ile ilişkili risk faktörleri. Veterinerlik Biliminde
Araştırma , 94 (2), 225-227.
- Kalogianni, A. I., Bossis, I., Ekateriniadou, L. V., & Gelasakis, A. I. (2020). Etiology, Epizootiology and Control of
Maedi-Visna in Dairy Sheep: A Review. Animals, 10(4), 616. DOI: https://doi.org/10.3390/ani10040616
- Karaoğlu, T. (2003). Küçük aile işletmelerindeki koyunlarda maedi-visna enfeksiyonunun seroprevalansı.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 50,123-126.
- Lopez, A., & Martinson, S.A. (2017). Respiratory system, mediastinum, and pleurae. Pathologic basis of veterinary
disease,( pp.471–560.e1.). Illinois
- Minguijón, E., Reina, R., Pérez, M., Polledo, L., Villoria, M., Ramírez, H., Leginagoikoa, I., Badiola, J.J., García-Marín,
J.F., D de Andrés , Luján, L., Amorena, B., & Juste, R. A. (2015). Small ruminant lentivirus infections and diseases.
Veterinary Microbiology, 181(1-2), 75-89. DOI: https://doi.org/10.1016/j.vetmic.2015.08.007
- Muz, D., Oğuzoğlu, T. Ç., Rosati, S., Reina, R., Bertolotti, L., & Burgu, I. (2013). First molecular characterization of
visna/maedi viruses from naturally infected sheep in Turkey. Archives of Virology, 158, 559-570. DOI:
10.1007/s00705-012-1518-1
- Nowicka, D., Czopowicz, M., Mickiewicz, M., Szalus-Jordanow, O., Witkowski, L., Bagnicka, E., & Kaba, J. (2014).
Diagnostic performance of ID ScreenR MVV-CAEV Indirect Screening ELISA in identifying small ruminant
lentiviruses-infected goats. Polish journal of veterinary sciences, 17(3).
- Peterhans, E., Greenland, T., Badiola, J., Harkiss, G., Bertoni, G., Amorena, B., Eliaszewicz, M., Juste, R.A., Krassnig, R.,
Lafont, J.R., Lenihan, P., Pétursson, G., Pritchard, G., Thorley, J., Vitu, C., Mornex, J.F., & Pépin, M. (2004). Routes of
transmission and consequences of small ruminant lentiviruses (SRLVs) infection and eradication schemes.
Veterinary Research, 35(3), 257-274. DOI: 10.1051/vetres:2004014
- Pétursson, G., Matthíasdóttir, S., Svansson, V., Andrésdóttir, V., Georgsson, G., Martin, A. H., & Torsteinsdóttir, S.
(2005). Mucosal vaccination with an attenuated maedi–visna virus clone. Vaccine, 23(24), 3223-3228.
- Preziuso, S., Or, M. E., Giammarioli, M., Kayar, A., Feliziani, F., Gönül, R., Farnetı, S., Parkan- Yaramış, C., Valente, C., &
Cuteri, V. (2010). Maedi-visna virus in Turkish sheep: a preliminary serological survey using ELISA tests. Turkish
Journal of Veterinary & Animal Sciences, 34(3), 289-293. DOI: 10.3906/vet-0905-35
- Preziuso, S., Sanna, E., Sanna, M. P., Loddo, C., Cerri, D., Taccini, E., Mariotti, F., Braca, G., Rossi, G., & Renzoni G.
(2003). Association of Maedi Visna virus with Brucella ovis infection in rams. European Journal of
Histochemistry, 47(2), 151-158. DOI: 10.4081/821
- Reina, R., Berriatua, E., Luján, L., Juste, R., Sánchez, A., de Andrés, D., & Amorena, B. (2009). Prevention strategies
against small ruminant lentiviruses: an update. The Veterinary Journal, 182(1), 31-37. DOI:
10.1016/j.tvjl.2008.05.008
- Riggio, S., Di Gerlando, R., Mastrangelo, S., Rizzuto, I., Tolone, M., & Sardina, M.T. (2023). Maedi Visna virus infection
and TMEM154 genotypes in Valle del Belìce sheep breed. Italian Journal of Animal Science, 22(1), 754-759.
DOI:https://doi.org/10.1080/1828051X.2023.2243095
- Schaller, P., Vogt, H. R., Strasser, M., Nettleton, P. F., Peterhans, E., & Zanoni, R. (2000). Seroprevalence of maedi-
visna and border disease in Switzerland. Schweizer Archiv fur Tierheilkunde, 142(4), 145-153.
- Schreuder, B.E.C., Yonguç, A.D., Girgin, H., & Akçora, A. (1988). Antibodies to maedi-visna in indigenous sheep in
eastern Turkey. Etlik Veteriner Mikrobiyoloji Dergisi, 1988 6 (3).
- Sigurdsson, B., Grímsson, H., & Pálsson, P. A. (1952). Maedi, a chronic, progressive infection of sheep's lungs. The
Journal of Infectious Diseases, 90(3), 233-241. DOI: 10.1093/infdis/90.3.233
- Straub, O.C. (2004). Maedi–Visna virus infection in sheep. History and present knowledge. Comparative
Immunology, Microbiology and Infectious Diseases, 27(1), 1-5. DOI:10.1016/S0147-9571(02)00078-4
- Tan, M. T., & Alkan, F. (2002). Türkiye'de maedi-visna enfeksiyonunun seroepidemiyolojisi ve virus izolasyonu.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 49(1), 45-50. DOI:https://doi.org/10.1501/Vetfak_0000001646
- Torsteinsdóttir, S., Carlsdóttir, H. M., Svansson, V., Matthíasdóttir, S., Martin, A. H., & Pétursson, G. (2007).
Vaccination of sheep with Maedi-visna virus gag gene and protein, beneficial or harmful?. Vaccine, 25(37-38),
6713-6720. DOI: 10.1016/j.vaccine.2007.07.004
- Ün, H., Özgünlük, İ., & Çabalar, M. (2018). Serologically investigation of maedi-visna virus infection (MVV) in
Șanlıurfa precincts. Harran Üniversitesi Veteriner Fakültesi Dergisi; 7 (2): 144-148. DOI:
https://doi.org/10.31196/huvfd.508962
- White, S. N., & Knowles, D. P. (2013). Expanding possibilities for intervention against small ruminant lentiviruses
through genetic marker-assisted selective breeding. Viruses, 5(6), 1466-1499. DOI: 10.3390/v5061466
- World Organisation for Animal Health: (WOAH). WOAH Terrestrial Manual 2018
- Yaman, Y., Keleş, M., Aymaz, R., Sevim, S., Sezenler, T., Önaldı, A. T., Kaptana, C., Başkurta,A., Seyrani K., Öner, Y.,
Öztürk, E.E., İriadam, M., Ün,C., & Heaton, M. P. (2019). Association of TMEM154 variants with visna/maedi virus
infection in Turkish sheep. Small Ruminant Research, 177, 61-67
- Zhang, K-s., He, J-j., Liu, Y-j., Shang, Y-j., & Liu, X-t. (2013). A seroprevalence survey of Maedi-Visna among
twenty-four ovine floks from twelve regions of China. Journal of Integrative Agriculture. 2013;12(12):2321-3. DOI:
10.1016/S2095-3119(13)60380-9
Yıl 2024,
Cilt: 14 Sayı: 1, 40 - 47, 28.06.2024
Hanne Nur Kuruçay
,
Bahadir Müftüoğlu
,
Seda Gözel
,
Ahmed Eısa Elhag
,
Cüneyt Tamer
,
Semra Gümüşova
,
Harun Albayrak
Kaynakça
- Akkan, H.A., Karaca, M., Tütüncü, M., Keles, I., Ilhan, F., Cetin, Y., & Tasal, I. (2009). Investigation of the
seroprevalance of maedi-visna in the region of Van using Elisa and histopathological findings. Journal of
Animal and Veterinary Advances, 8(8), 1495-1498
- Albayrak, H., Yazici, Z., Okur-Gumusova, S., & Ozan, E. (2012). Maedi-visna virus infection in Karayaka and
Amasya Herik breed sheep from provinces in northern Turkey. Tropical Animal Health and Production, 44, 939-
941. DOI: 10.1007/s11250-011-9996-9
- Alibaşoglu, M., & Arda, M. (1975). Koyun pulmoner adenomatozisi'nin Türkiye'de durumu ile patolojisi ve
etiyolojisinin araştırılması. Tübitak Vhag Yayınları, 274.
- Arık, C., Acar, A., & Gür, S. (2015). Afyonkarahisar İli ve Çevresinde Maedi-Visna Virüs Enfeksiyonunun Klinik ve
Serolojik Olarak Araştırılması. Kocatepe Veterinary Journal, 8(1): 39-44. DOI: 10.5578/kvj.8985
- Arslan, S., Savsunlu, Z., Vural, T., Arslan, H., Yüksel, M., Şelli, M. Ş., & Çabalar, M. (2012). Şanlıurfa ilindeki koyunlarda
maedi-visna enfeksiyonunun varlığı ve yaygınlığının araştırılması. 10. Ulusal Veteriner Hekimleri Mikrobiyoloji
Kongresi, 24(27), 374.
- Azkur, A. K., Gazyagci, S., & Aslan, M. E. (2011). Serological and epidemiological investigation of bluetongue,
Maedi-Visna and caprine arthritis-encephalitis viruses in small ruminant in Kirikkale District in Turkey. Kafkas
Universitesi Veteriner Fakultesi Dergisi 17 (5): 803-808. DOI:10.9775/kvfd.2011.4492.
- Blacklaws, B.A. (2012). Small ruminant lentiviruses: Immunopathogenesis of visna-maedi and caprine arthritis
and encephalitis virus. Comparative İmmunology, Microbiology and Infectious Diseases, 35(3), 259-269. DOI:
10.1016/j.cimid.2011.12.003
- Blacklaws, B.A., Berriatua, E., Torsteinsdottir, S., Watt, N.J., Andres, D. De., Klein, D., & Harkiss, G.D. (2004).
Transmission of small ruminant lentiviruses. Veterinary Microbiology., 101 (2004), pp. 199-208,
10.1016/j.vetmic.2004.04.006
- De Boer, G.F., & Houwers, D.J. (1979). Epizootiology of maedi/visna in sheep. In Aspects of Slow and Persistent
Virus Infections: Proceedings of the European Workshop sponsored by the Commission of the European
Communities on the advice of the Committee on Medical and Public Health Research, held in London (UK),
April 5–6, 1979 (pp. 198-221). Dordrecht: Springer Netherlands.
- Broughton-Neiswanger, L. E., White, S. N., Knowles, D. P., Mousel, M. R., Lewis, G. S., Herndon, D. R., & Herrmann-
Hoesing, L. M. (2010). Non-maternal transmission is the major mode of ovine lentivirus transmission in a ewe
flock: A molecular epidemiology study. Infection, Genetics and Evolution, 10(7), 998-1007. DOI:
10.1016/j.meegid.2010.06.007
- Burgu, I., Toker, A., Akca, Y., Alkan, F., Yazıcı, Z., & Özkul, A. 1990. Serological studies on visna maedi virus infection
of sheep in Turkey. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 37 (3) : 538-553.
https://doi.org/10.1501/Vetfak_0000001331
- Cheevers, W. P., Knowles, D. P., McGuire, T. C., Baszler, T. V., & Hullinger, G. A. (1994). Caprine arthritis-encephalitis
lentivirus (CAEV) challenge of goats immunized with recombinant vaccinia virus expressing CAEV surface and
transmembrane envelope glycoproteins. Veterinary Immunology and Immunopathology, 42(3-4), 237-251.
DOI: 10.1016/0165-2427(94)90070-1
- Christodoulopoulos, G. (2006). Maedi–Visna: Clinical review and short reference on the disease status in
Mediterranean countries. Small Ruminant Research, 62(1-2), 47-53. DOI: 10.1016/j.smallrumres.2005.07.046
- Çimtay, İ., Keskin, O., & Şahin, T. (2004). Şanlıurfa yöresinde koyun ve keçilerde bazı lentivirus enfeksiyonlarının
araştırılması. Journal of Research in Veterinary Medicine, 23, 1-2-3: 33-38.
- Dawson, M. (1980). Maedi/visna: a review. The Veterinary Record, 106(10), 212-216. DOI: 10.1136/vr.106.10.212
- De Boer, G.F.(1975). Zwoegerziekte virus, the causative agent for progressive interstitial pneumonia (maedi)
and meningo-leucoencephalitis (visna) in sheep. Research in Veterinary Science. 18, 15–25.
- Gezer, T., Akyüz, E., & Gökçe, G. (2021). Investigation of Seroprevalence of Maedi-Visna Infection in some sheep
flocks in Kars province, Turkey. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 14(1), 48-51. DOI:
https://doi.org/10.47027/duvetfd.881430
- Girgin, H., Aydın, N., Yonguç, A. D., Aksoy, E., & Çorak, R. (1987). Ve şimdi koyunların viral maedi-visna'sı Türkiye'de.
Etlik Veteriner Mikrobiyoloji Dergisi, 6(1), 9-22.
- Glaria, I., Reina, R., Ramirez, H., De Andres, X., Crespo, H., Jauregui, P., Salazar, E., Luján, L., Pérez, M.M., Benavides, J.,
Pérez, V., Polledo, L., García-Marín, J.F., Riezu, J.I., Borrás, F., Amorena, B., & De Andrés, D. (2012). Visna/Maedi
virus genetic characterization and serological diagnosis of infection in sheep from a neurologicaloutbreak.
Veterinary microbiology, 155(2-4), 137-146. https://doi.org/10.1016/j.vetmic.2011.08.027
- Gomez-Lucia, E., Barquero, N., & Domenech, A. (2018). Maedi-Visna virus: current perspectives. Veterinary
Medicine: Research and Reports, 11-21. DOI: 10.2147/VMRR.S136705
- González, B., Reina, R., García, I., Andrés, S., Glaria, I., Alzueta, M., Mora, M.I., Jugo, B.M., Arrieta-Aguirre,I., de la
Lastra,J.M.P., Rodríguez, D.,Rodríguez, J.R., Esteban, M., Grilló, M.J., Barbara, A.B., Harkiss, G.D., Chebloune, Y.,
Luján, L., de Andrés D., & Amorena, B. (2005). Mucosal immunization of sheep with a Maedi-Visna virus (MVV)
env DNA vaccin protects against early MVV productive infection. Vaccine, 23(34), 4342-4352. DOI:
10.1016/j.vaccine.2005.03.032
- Gürçay, M., & Parmaksız, A. (2013). An investigation of Visna-Maedi virus infection in Şanlıurfa Province,
Southeast Anatolia, Turkey. Adana Veteriner Kontrol Enstitüsü Müdürlüğü Dergisi, 3(1), 46-50.
- Heaton, M. P., Kalbfleisch, T. S., Petrik, D. T., Simpson, B., Kijas, J. W., Clawson, M. L., Carol, G.C.Mc., Gregory, P.H.,
Kreg, A.L., & International Sheep Genomics Consortium. (2013). Genetic testing for TMEM154 mutations
associated with lentivirus susceptibility in sheep. PloS One, 8(2), e55490.
- International Committee on Taxonomy of Viruses: ICTV.2023 https://ictv.global/taxonomy.
- Kaba, J., Czopowicz, M., Ganter, M., Nowicki, M., Witkowski, L., Nowicka, D., & Szaluś-Jordanow, O. (2013). Keçi
sürülerinde küçük ruminant lentivirüslere karşı seropozitiflik ile ilişkili risk faktörleri. Veterinerlik Biliminde
Araştırma , 94 (2), 225-227.
- Kalogianni, A. I., Bossis, I., Ekateriniadou, L. V., & Gelasakis, A. I. (2020). Etiology, Epizootiology and Control of
Maedi-Visna in Dairy Sheep: A Review. Animals, 10(4), 616. DOI: https://doi.org/10.3390/ani10040616
- Karaoğlu, T. (2003). Küçük aile işletmelerindeki koyunlarda maedi-visna enfeksiyonunun seroprevalansı.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 50,123-126.
- Lopez, A., & Martinson, S.A. (2017). Respiratory system, mediastinum, and pleurae. Pathologic basis of veterinary
disease,( pp.471–560.e1.). Illinois
- Minguijón, E., Reina, R., Pérez, M., Polledo, L., Villoria, M., Ramírez, H., Leginagoikoa, I., Badiola, J.J., García-Marín,
J.F., D de Andrés , Luján, L., Amorena, B., & Juste, R. A. (2015). Small ruminant lentivirus infections and diseases.
Veterinary Microbiology, 181(1-2), 75-89. DOI: https://doi.org/10.1016/j.vetmic.2015.08.007
- Muz, D., Oğuzoğlu, T. Ç., Rosati, S., Reina, R., Bertolotti, L., & Burgu, I. (2013). First molecular characterization of
visna/maedi viruses from naturally infected sheep in Turkey. Archives of Virology, 158, 559-570. DOI:
10.1007/s00705-012-1518-1
- Nowicka, D., Czopowicz, M., Mickiewicz, M., Szalus-Jordanow, O., Witkowski, L., Bagnicka, E., & Kaba, J. (2014).
Diagnostic performance of ID ScreenR MVV-CAEV Indirect Screening ELISA in identifying small ruminant
lentiviruses-infected goats. Polish journal of veterinary sciences, 17(3).
- Peterhans, E., Greenland, T., Badiola, J., Harkiss, G., Bertoni, G., Amorena, B., Eliaszewicz, M., Juste, R.A., Krassnig, R.,
Lafont, J.R., Lenihan, P., Pétursson, G., Pritchard, G., Thorley, J., Vitu, C., Mornex, J.F., & Pépin, M. (2004). Routes of
transmission and consequences of small ruminant lentiviruses (SRLVs) infection and eradication schemes.
Veterinary Research, 35(3), 257-274. DOI: 10.1051/vetres:2004014
- Pétursson, G., Matthíasdóttir, S., Svansson, V., Andrésdóttir, V., Georgsson, G., Martin, A. H., & Torsteinsdóttir, S.
(2005). Mucosal vaccination with an attenuated maedi–visna virus clone. Vaccine, 23(24), 3223-3228.
- Preziuso, S., Or, M. E., Giammarioli, M., Kayar, A., Feliziani, F., Gönül, R., Farnetı, S., Parkan- Yaramış, C., Valente, C., &
Cuteri, V. (2010). Maedi-visna virus in Turkish sheep: a preliminary serological survey using ELISA tests. Turkish
Journal of Veterinary & Animal Sciences, 34(3), 289-293. DOI: 10.3906/vet-0905-35
- Preziuso, S., Sanna, E., Sanna, M. P., Loddo, C., Cerri, D., Taccini, E., Mariotti, F., Braca, G., Rossi, G., & Renzoni G.
(2003). Association of Maedi Visna virus with Brucella ovis infection in rams. European Journal of
Histochemistry, 47(2), 151-158. DOI: 10.4081/821
- Reina, R., Berriatua, E., Luján, L., Juste, R., Sánchez, A., de Andrés, D., & Amorena, B. (2009). Prevention strategies
against small ruminant lentiviruses: an update. The Veterinary Journal, 182(1), 31-37. DOI:
10.1016/j.tvjl.2008.05.008
- Riggio, S., Di Gerlando, R., Mastrangelo, S., Rizzuto, I., Tolone, M., & Sardina, M.T. (2023). Maedi Visna virus infection
and TMEM154 genotypes in Valle del Belìce sheep breed. Italian Journal of Animal Science, 22(1), 754-759.
DOI:https://doi.org/10.1080/1828051X.2023.2243095
- Schaller, P., Vogt, H. R., Strasser, M., Nettleton, P. F., Peterhans, E., & Zanoni, R. (2000). Seroprevalence of maedi-
visna and border disease in Switzerland. Schweizer Archiv fur Tierheilkunde, 142(4), 145-153.
- Schreuder, B.E.C., Yonguç, A.D., Girgin, H., & Akçora, A. (1988). Antibodies to maedi-visna in indigenous sheep in
eastern Turkey. Etlik Veteriner Mikrobiyoloji Dergisi, 1988 6 (3).
- Sigurdsson, B., Grímsson, H., & Pálsson, P. A. (1952). Maedi, a chronic, progressive infection of sheep's lungs. The
Journal of Infectious Diseases, 90(3), 233-241. DOI: 10.1093/infdis/90.3.233
- Straub, O.C. (2004). Maedi–Visna virus infection in sheep. History and present knowledge. Comparative
Immunology, Microbiology and Infectious Diseases, 27(1), 1-5. DOI:10.1016/S0147-9571(02)00078-4
- Tan, M. T., & Alkan, F. (2002). Türkiye'de maedi-visna enfeksiyonunun seroepidemiyolojisi ve virus izolasyonu.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 49(1), 45-50. DOI:https://doi.org/10.1501/Vetfak_0000001646
- Torsteinsdóttir, S., Carlsdóttir, H. M., Svansson, V., Matthíasdóttir, S., Martin, A. H., & Pétursson, G. (2007).
Vaccination of sheep with Maedi-visna virus gag gene and protein, beneficial or harmful?. Vaccine, 25(37-38),
6713-6720. DOI: 10.1016/j.vaccine.2007.07.004
- Ün, H., Özgünlük, İ., & Çabalar, M. (2018). Serologically investigation of maedi-visna virus infection (MVV) in
Șanlıurfa precincts. Harran Üniversitesi Veteriner Fakültesi Dergisi; 7 (2): 144-148. DOI:
https://doi.org/10.31196/huvfd.508962
- White, S. N., & Knowles, D. P. (2013). Expanding possibilities for intervention against small ruminant lentiviruses
through genetic marker-assisted selective breeding. Viruses, 5(6), 1466-1499. DOI: 10.3390/v5061466
- World Organisation for Animal Health: (WOAH). WOAH Terrestrial Manual 2018
- Yaman, Y., Keleş, M., Aymaz, R., Sevim, S., Sezenler, T., Önaldı, A. T., Kaptana, C., Başkurta,A., Seyrani K., Öner, Y.,
Öztürk, E.E., İriadam, M., Ün,C., & Heaton, M. P. (2019). Association of TMEM154 variants with visna/maedi virus
infection in Turkish sheep. Small Ruminant Research, 177, 61-67
- Zhang, K-s., He, J-j., Liu, Y-j., Shang, Y-j., & Liu, X-t. (2013). A seroprevalence survey of Maedi-Visna among
twenty-four ovine floks from twelve regions of China. Journal of Integrative Agriculture. 2013;12(12):2321-3. DOI:
10.1016/S2095-3119(13)60380-9