Elli Yaş Altı Meme Kanseri Hastalarında Modifiye Radikal Mastektomi ve Meme Koruyucu Cerrahinin Yaşam Kalitesi Açısından Karşılaştırılması

Öz

Amaç: Meme koruyucu cerrahi (MKC) ve modifiye radikal mastektomi (MRM) uygulanmış meme kanserli hastaların yaşam kalitelerinin karşılaştırılması. Gereç ve Yöntemler: Kırk dört adet MKC ve 27 adet MRM uygulanmış meme kanserli kadın hasta bu retrospektif çalışmaya dahil edilmiştir. Tüm hastalar adjuvan kemoterapi ve radyoterapilerini tamamlamıştır. MRM sonrası meme rekonstrüksiyonu yapılanlar, lokal ya da uzak organda tekrarlama gelişenler ve elli yaşın üstünde olanlar çalışmadan çıkarılmıştır. Tüm tedavilerin tamamlanmasından 6 ay sonra hastaların yaşam kalitesi Kısa Form 36 (SF-36) ile değerlendirilmiştir. Bulgular: MKC ve MRM grupları arasında yaş, boy, ağırlık ve vücut kitle indeksi açısından anlamlı fark yoktu. SF-36 ölçeklerinden fiziksel fonksiyon, fiziksel rol güçlüğü, duygusal rol güçlüğü, sosyal rol güçlüğü, ağrı ve genel sağlık algısı ölçeklerinde MKC grubunda MRM grubuna oranla daha iyi sonuçlar çıkmasına rağmen anlamlı fark bulunmazken, sadece vitalite ve ruhsal sağlık ölçeklerinde MKC grubunun değerleri MRM grubunun değerlerinden istatistiksel anlamda daha iyi bulundu (sırasıyla p= 0.043 ve p= 0.023). Sonuç: Meme kanseri tedavisinde hastaların yaşam kalitesinin artırılması sağkalımı uzatmak kadar önemlidir. Çalışmamızda MKC hastalarında daha yüksek yaşam kalitesi olduğu gösterilmiştir, özellikle SF-36 ölçeklerinden vitalite ve ruhsal sağlık, MRM grubuna göre istatistiki anlamlı olacak şekilde daha iyi bulunmuştur.

Anahtar Kelimeler

• Meme kanseri
• Yaşam kalitesi
• Mastektomi
• Meme koruyucu cerrahi

A Comparison Between Modified Radical Mastectomy and Breast-Conserving Surgery Concerning the Quality of Life in Patients with Breast Cancer Under 50 Years of Age

Öz

surgery (BCS) to those having undergone modified radical mastectomy (MRM). Material and Methods: Forty-four BCS and 27 MRM patients have been included in this retrospective study. All patients have completed adjuvant chemotherapies and radiation therapies. MRM patients who received breast reconstruction surgery afterwards, patients who experienced local or distant organ relapse, or patients over fifty years old have been excluded. Each patient’s quality of life has been evaluated using the Short Form 36 (SF-36), 6 months after the completion of their treatment. Results: Between BCS and MRM groups, no significant difference of age, height, weight and body mass index was observed. While the BCS group yielded better results from the SF-36 subscales, i.e. physical functioning, physical role functioning, emotional role functioning, social role functioning, bodily pain, and general health perceptions, the only measures illustrating a significant difference were vitality and mental health, in comparison of BCS with MRM group (p= 0.043 and p= 0.023, respectively). Conclusion: In the treatment of breast cancer, enhancing patients’ quality of life is just as essential as improving survivals. Our research demonstrates higher quality of life in BCS patients, highlighting the statistical difference of the vitality and mental health subscales of the SF-36, compared with the MRM group.

Anahtar Kelimeler

• Breast cancer
• Quality of life
• Mastectomy
• Breast-conserving surgery

Kaynakça

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