Adult Tracheobronchomalacia that Progressed Following Radiotherapy in an Advanced-stage Lung Cancer Patient: A Rare Case Report
Yıl 2024,
Cilt: 8 Sayı: 2, 201 - 206, 30.08.2024
Hülya Abalı
,
Seda Tural Önür
,
Aslı Biçen
,
Kaan Kara
Öz
Tracheobronchomalacia (TBM) is the collapse of the trachea and bronchi, which leads to respiratory symptoms and complications, often on forced expiration. Radiotherapy (RT) is a rare cause of adult TBM.
Here, we report the first case of progressive TBM following palliative RT in a patient with squamous cell lung carcinoma. TBM was diagnosed by fiberoptic bronchoscopy and thoracic CT scans.
In patients with advanced-stage lung cancer who experience worsening dyspnea and cough following palliative RT, TBM should also be taken into account.
Etik Beyan
This retrospective review of patient data did not require ethical approval in accordance with local/national guidelines. The authors state that they have followed the principles outlined in the Declaration of Helsinki for all human or animal experimental investigations. Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Kaynakça
- 1. Nuutinen J. Acquired tracheobronchomalacia. A clinical study
with bronchological correlations. Ann Clin Res 1977;9(6):350-
355.
- 2. Murgu SD, Colt HG. Treatment of adult tracheobronchomalacia
and excessive dynamic airway collapse: an update. Treat
Respir Med 2006;5(2):103-115.
- 3. Buitrago DH, Wilson JL, Parikh A, Majid A, Gangadharan SP.
Current concepts in severe adult tracheobronchomalacia: evaluation
and treatment. J Thorac Dis 2017;9(1):E57-E66.
- 4. Murgu S, Colt H. Tracheobronchomalacia and excessive dynamic
airway collapse. Clin Chest Med 2013;34(3):527-555.
- 5. Kamran A, Baird CW, Jennings RW. Tracheobronchomalacia,
Tracheobronchial Compression, and Tracheobronchial Malformations:
Diagnostic and Treatment Strategies. Semin Thorac
Cardiovasc Surg Pediatr Card Surg Annu 2020;23:53-61.
- 6. Wright CD. Tracheobronchomalacia and expiratory collapse of
central airways. Thorac Surg Clin 2018;28(2):163-166.
- 7. Kano Y, Sakurai H, Shidara J, Toida S, Yasuda H. Histopathological
and immunohistochemical studies of acquired tracheobronchomalacia:
an autopsy case report. ORL J Otorhinolaryngol
Relat Spec 1996;58(5):288-294.
- 8. Jokinen K, Palva T, Sutinen S, Nuutinen J. Acquired tracheobronchomalacia.
Ann Clin Res 1077;9(2):52-57.
- 9. Brody AS, Kuhn JP, Seidel FG, Brodsky LS. Airway evaluation
in children with use of ultrafast CT: pitfalls and recommendations.
Radiology 1991;178(1):181-184.
- 10. Larici AR, del Ciello A, Maggi F, Santoro SI, Meduri B, Valentini
V, Giordano A, Bonomo L. Lung abnormalities at multimodality
imaging after radiation therapy for non-small cell lung cancer.
Radiographics 2011;31(3):771-889.
- 11. Choi YW, Munden RF, Erasmus JJ, Park KJ, Chung WK, Jeon
SC, Park C-K. Effects of radiation therapy on the lung: radiologic
appearances and differential diagnosis. Radiographics 2004;
24(4):985-997.
- 12. Dutau H, Laroumagne S, Bylicki O, Vandemoortele T. Tracheobronchomalacia
in adults: breakthroughs and controversies.
Astoul P.Rev Mal Respir 2012;29(10):1198-1208.
- 13. Carden KA, Boiselle PM, Waltz DA, Ernst A. Tracheomalacia
and tracheobronchomalacia in children and adults: an in-depth
review. Chest 2005;127(3):984-1005.
- 14. Biswas A, Jantz MA, Sriram PS, Mehta HJ. Tracheobronchomalacia.
Dis Mon 2017;63(10):287-302.
- 15. Gangadharan SP, Mathew F. Thermoablative Techniques to
Treat Excessive Central Airway Collapse. Thorac Surg Clin
2023;33(3):299-308.
- 16. Lee KS, Sun MRM, Ernst A, Feller-Kopman D, Majid A, Boiselle
PM. Comparison of dynamic expiratory CT with bronchoscopy
for diagnosing airway malacia: a pilot evaluation. Chest
2007;131(3):758-764.
- 17. Lee EY, Litmanovich D, Boiselle PM. Multidetector CT evaluation
of tracheobronchomalacia. Radiol Clin North Am
2009;47(2):261-269.
- 18. Majid A, Gaurav K, Sanchez JM, Berger RL, Folch E, Fernandez-
Bussy S, Ernst A, Gangadharan SP. Evaluation of tracheobronchomalacia
by 34 dynamic flexible bronchoscopy. A pilot
study. Ann Am Thorac Soc 2014;11(6):951-955.
- 19. Aquino SL, Shepard JA, Ginns LC, Moore RH, Halpern E, Grillo
HC, McLoud TC. Acquired tracheomalacia, detection by expiratory
CT scan. J Comput Assist Tomogr 2001;25(3):394-399.
- 20. Pezzuto A, Ricci A, D’Ascanio M, Moretta A, Tonini G, Calabrò
N, Minoia V, Pacini A, Paolis GD, Chichi E, Carico E, Tammaro
A. Short-Term Benefits of Smoking Cessation Improve Respiratory
Function and Metabolism in Smokers. Int J Chron Obstruct
Pulmon Dis 2023;18:2861-2865.
- 21. Santos Portela AM, Radu DM, Onorati I, Peretti M, Freynet O,
Uzunhan Y, Jerbi S, Martinod E. Interventionnal bronchoscopy
for the treatment of tracheobronchomalacia. Rev Mal Respir
2023;40(8):700-715.
İleri Evre Akciğer Kanseri Hastasında Radyoterapi Sonrası İlerleyen Erişkin Trakeobronkomalazi: Nadir Bir Olgu
Yıl 2024,
Cilt: 8 Sayı: 2, 201 - 206, 30.08.2024
Hülya Abalı
,
Seda Tural Önür
,
Aslı Biçen
,
Kaan Kara
Öz
Trakeobronkomalazi (TBM), sıklıkla zorlu ekspirasyon sırasında solunum semptomlarına ve komplikasyonlara yol açan trakea ve bronşların kollapsıdır. Radyoterapi (RT) erişkin TBM'nin nadir bir nedenidir.
Burada, skuamöz hücreli akciğer karsinomlu bir hastada palyatif RT'yi takiben ilerleyen ilk TBM vakasını sunuyoruz. TBM tanısı fiberoptik bronkoskopi ve toraks BT taramaları ile konuldu.
Palyatif RT'yi takiben nefes darlığı ve öksürüğü artan ileri evre akciğer kanserli hastalarda TBM de dikkate alınmalıdır.
Kaynakça
- 1. Nuutinen J. Acquired tracheobronchomalacia. A clinical study
with bronchological correlations. Ann Clin Res 1977;9(6):350-
355.
- 2. Murgu SD, Colt HG. Treatment of adult tracheobronchomalacia
and excessive dynamic airway collapse: an update. Treat
Respir Med 2006;5(2):103-115.
- 3. Buitrago DH, Wilson JL, Parikh A, Majid A, Gangadharan SP.
Current concepts in severe adult tracheobronchomalacia: evaluation
and treatment. J Thorac Dis 2017;9(1):E57-E66.
- 4. Murgu S, Colt H. Tracheobronchomalacia and excessive dynamic
airway collapse. Clin Chest Med 2013;34(3):527-555.
- 5. Kamran A, Baird CW, Jennings RW. Tracheobronchomalacia,
Tracheobronchial Compression, and Tracheobronchial Malformations:
Diagnostic and Treatment Strategies. Semin Thorac
Cardiovasc Surg Pediatr Card Surg Annu 2020;23:53-61.
- 6. Wright CD. Tracheobronchomalacia and expiratory collapse of
central airways. Thorac Surg Clin 2018;28(2):163-166.
- 7. Kano Y, Sakurai H, Shidara J, Toida S, Yasuda H. Histopathological
and immunohistochemical studies of acquired tracheobronchomalacia:
an autopsy case report. ORL J Otorhinolaryngol
Relat Spec 1996;58(5):288-294.
- 8. Jokinen K, Palva T, Sutinen S, Nuutinen J. Acquired tracheobronchomalacia.
Ann Clin Res 1077;9(2):52-57.
- 9. Brody AS, Kuhn JP, Seidel FG, Brodsky LS. Airway evaluation
in children with use of ultrafast CT: pitfalls and recommendations.
Radiology 1991;178(1):181-184.
- 10. Larici AR, del Ciello A, Maggi F, Santoro SI, Meduri B, Valentini
V, Giordano A, Bonomo L. Lung abnormalities at multimodality
imaging after radiation therapy for non-small cell lung cancer.
Radiographics 2011;31(3):771-889.
- 11. Choi YW, Munden RF, Erasmus JJ, Park KJ, Chung WK, Jeon
SC, Park C-K. Effects of radiation therapy on the lung: radiologic
appearances and differential diagnosis. Radiographics 2004;
24(4):985-997.
- 12. Dutau H, Laroumagne S, Bylicki O, Vandemoortele T. Tracheobronchomalacia
in adults: breakthroughs and controversies.
Astoul P.Rev Mal Respir 2012;29(10):1198-1208.
- 13. Carden KA, Boiselle PM, Waltz DA, Ernst A. Tracheomalacia
and tracheobronchomalacia in children and adults: an in-depth
review. Chest 2005;127(3):984-1005.
- 14. Biswas A, Jantz MA, Sriram PS, Mehta HJ. Tracheobronchomalacia.
Dis Mon 2017;63(10):287-302.
- 15. Gangadharan SP, Mathew F. Thermoablative Techniques to
Treat Excessive Central Airway Collapse. Thorac Surg Clin
2023;33(3):299-308.
- 16. Lee KS, Sun MRM, Ernst A, Feller-Kopman D, Majid A, Boiselle
PM. Comparison of dynamic expiratory CT with bronchoscopy
for diagnosing airway malacia: a pilot evaluation. Chest
2007;131(3):758-764.
- 17. Lee EY, Litmanovich D, Boiselle PM. Multidetector CT evaluation
of tracheobronchomalacia. Radiol Clin North Am
2009;47(2):261-269.
- 18. Majid A, Gaurav K, Sanchez JM, Berger RL, Folch E, Fernandez-
Bussy S, Ernst A, Gangadharan SP. Evaluation of tracheobronchomalacia
by 34 dynamic flexible bronchoscopy. A pilot
study. Ann Am Thorac Soc 2014;11(6):951-955.
- 19. Aquino SL, Shepard JA, Ginns LC, Moore RH, Halpern E, Grillo
HC, McLoud TC. Acquired tracheomalacia, detection by expiratory
CT scan. J Comput Assist Tomogr 2001;25(3):394-399.
- 20. Pezzuto A, Ricci A, D’Ascanio M, Moretta A, Tonini G, Calabrò
N, Minoia V, Pacini A, Paolis GD, Chichi E, Carico E, Tammaro
A. Short-Term Benefits of Smoking Cessation Improve Respiratory
Function and Metabolism in Smokers. Int J Chron Obstruct
Pulmon Dis 2023;18:2861-2865.
- 21. Santos Portela AM, Radu DM, Onorati I, Peretti M, Freynet O,
Uzunhan Y, Jerbi S, Martinod E. Interventionnal bronchoscopy
for the treatment of tracheobronchomalacia. Rev Mal Respir
2023;40(8):700-715.