Beyin Sağlığını Korumada Egzersizin Önemi

Öz

Beyin sağlığının korunmasında farmakolojik olmayan müdahaleler arasında egzersiz, en etkili stratejilerden biri olarak öne çıkmaktadır. Egzersiz nörotrofik faktörlerin artışını destekler, beyin perfüzyonunu iyileştirir, nöroinflamasyonu azaltır ve oksidatif stresin modülasyonunu sağlar. Aerobik egzersizler, beyin kaynaklı nörotrofik faktör (BDNF) düzeylerini artırarak hipokampal nörogenezi teşvik eder, hafıza ve yürütücü işlevler gibi bilişsel fonksiyonları geliştirir. Direnç egzersizleri ise insülin benzeri büyüme faktörü-1 (IGF-1) düzeylerini artırarak yürütücü işlevlere katkı sağlar. Aerobik ve direnç egzersizlerinin birlikte uygulanması, tamamlayıcı mekanizmalar üzerinden daha geniş kapsamlı nöroprotektif etkiler sunabilir.

Anahtar Kelimeler

• Beyin
• Aerobik egzersiz
• BDNF
• Nörotrofik Faktörler
• Nörogenez

The Role of Exercise in Maintaining Brain Health

Öz

Exercise stands out as one of the most effective non-pharmacological strategies for maintaining brain health. It supports the increase of neurotrophic factors, improves cerebral perfusion, reduces neuroinflammation, and contributes to the modulation of oxidative stress. Aerobic exercise enhances brain-derived neurotrophic factor (BDNF) levels, thereby promoting hippocampal neurogenesis and improving cognitive functions such as memory and executive functions. Resistance training, on the other hand, increases insulin-like growth factor-1 (IGF-1) levels, which also contributes to improvements in executive functioning. The combined application of aerobic and resistance exercises may offer broader neuroprotective effects through complementary mechanisms.

Anahtar Kelimeler

• Brain
• Aerobic Exercise
• BDNF
• Neurotrophic Factors
• Neurogenesis

Kaynakça

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