Evaluation of Histopathological Findings in Patients Undergoing Laparoscopic Sleeve Gastrectomy Specimens

Yıl 2020, , 504 - 509, 15.09.2020

Funda Canaz , Evrim Yılmaz Özgül Paşaoğlu Deniz Arık , Adnan Şahin

https://doi.org/10.20515/otd.551907

Öz

Laparoscopic
sleeve gastrectomy (LSG) is a common surgical therapeuti coption in patients
with morbid obesity that debate about the value of routine histopathologi cal examination
of LSG. Also the effect of Helicobacterpylori colonization of the stomach of
patient sunder going LSG is unclear. Ouraim is to analyze there sults of
histopathological examination of LSG specimensan didentify the prevalence of
Helicobacterpylori. This study is a retrospective study of the patients who underwent
LSG for the treatment of morbid obesity in our hospital between  2014-2018. Sex, age, histopathologi
calfindings in the surgical specimens and prevalenceof  Helicobacterpylori(HP) infection were
analyzed. Gastricspecimens of a total of 110 patients( 90females, 20 males;
meanage 38 ± 11.9years)were analyzed in this study.Themost common
histopathological findings in the surgical specimens were chronicin  active gastritis (57.3%,n=63),chronic active
gastritis ( 34.5%, n= 38),intestinal metaplasia (6.4%, n=7), fundic gland polyp
(1.8%,n=2), parietal cellhy pertrophia (0.9 %, n=1). Fourty eight  (43.6%) patients were foundto be HP positive.
There was statistically significant correlation between gastritis and HP
infections. The majority of patients who underwent LSG had pathological
findings in resected specimens.It is concluded that the pathological evaluation
of the LSG specimens is necessary because of the clinical significance of HP
infection and intestinal metaplasia.

Anahtar Kelimeler

Laparoscopy;sleeve gastrectomy; histopathology

Laparoskopik Sleeve Gastrektomi Materyallerinde Histopatolojik Bulguların Değerlendirilmesi

Öz

Laparoskopik
sleeve gastrektomi (LSG) morbid obezitede sık kullanılan bir tedavi yöntemi
olup, bu spesmenlerde rutin histopatolojik incelemenin değeri tartışmalıdır.
Ayrıca LSG yapılan hastalarda midedeki HP kolonizasyonunun etkisi
bilinmemektedir. Bu çalışmada amacımız LSG spesmenlerindeki histopatolojik inceleme
sonuçlarını değerlendirmek ve HP prevalansını belirlemektir. Bu çalışma
hastanemizde 2014-2018 yılları arasında morbid obezite nedenli LSG yapılan
hastaları içeren retrospektif bir çalışmadır. Yaş, cinsiyet, cerrahi
spesmenlerdeki histopatolojik bulgular ve HP infeksiyon prevalansı
değerlendirildi. Bu çalışmada 110 hastanın (90 kadın, 20 erkek; ortalama yaş 38
± 11.9 yıl) gastrik spesmeni incelendi. Cerrahi spesmende sık gözlenen
histopatolojik bulgular kronik inaktif gastrit (%57.3, n=63), kronik aktif
gastrit ( %34.5, n= 38) intestinal metaplazi (%6.4, n=7), minimal atrofi (%12.7,
n=14), fundik gland polip (%1.8,n=2), nöroendokrin hücre hiperplazisi
(%1.8’inde, n=2),  pariyetal hücre
hipertrofisidir (%0.9 , n=1). Kırk sekiz hastada (%43.6) HP pozitifti. Gastrit
ve atrofi ile HP infeksiyonu arasında istatiksel olarak anlamlı korelasyon
saptandı p<0.001). LSG
yapılan olguların çoğunda histopatolojik değişiklikler saptanmıştır. H.P infeksiyonu,
atrofi ve intestinal metaplazinin klinik önemi nedeniyle LSG spesmenlerinin histopatolojik
değerlendirmesinin gerekli olduğu sonucuna varılmıştır.

Anahtar Kelimeler

Laparoskopi; sleeve gastrektomi; histopatoloji

Kaynakça

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