Soğuk Koni̇zasyon Endi̇kasyonlarının ve Sonuçlarının Değerlendi̇ri̇lmesi̇

Öz

Amaç: Bu çalışmanın amacı yüksek dereceli servikal lezyonların tedavisinde soğuk konizasyonunun etkinliğini ve endikasyonlarını belirlemektir. Materyal ve Metot: Bu çalışmaya 9 yıllık süreçte yüksek dereceli servikal lezyonu olan ve soğuk konizasyon ile tedavi edilen hastalar dahil edildi. Smear, kolposkopik biyopsi, soğuk konizasyon sonuçları ve mevcut total histerektomi spesimenleri arasında histopatolojik korelasyon yapıldı. Bulgular: Yüz otuz bir soğuk koni biyopsisi bu çalışma için analiz edildi. En sık görülen patoloji 64 (%48,9) ile CIN II-III idi. Diğer konizasyon sonuçları sıklık sırasına göre şöyledir; CIN I 29 (%22,1), Karsinom (Ca) 19 (%14,5) , servisit 14 (%10,7), negatif 5 (%3,8). Sonuç: Soğuk konizasyon, serviksin servikal intraepitelyal neoplazi (CIN) ve mikroinvaziv karsinomunun tedavisinde kabul edilebilir bir seçenek olmaya devam etmekte ayrıca tanısal ve terapötik etkinliği iyi bilinmektedir. Uygun şekilde yapıldığında, doğru bir histopatolojik tanı sağlar ve düşük komplikasyon riskine sahiptir; ayrıca çoğu vakada küratiftir. Elbette, mükemmel klinik sonuçlar yine de dikkatli, uzun süreli ve özenli bir takip gerektirmektedir.

Anahtar Kelimeler

• Servikal intraepitelyal neoplazi
• servikal smear
• soğuk konizasyon

Evaluation of Cold Conization Indications and Results

Abstract

Objective: The aim of this study was to determine the efficiency and indications of cold knife conization in the treatment of high-grade cervical lesions. Materials and Methods: This study included patients with high-grade cervical lesions treated with cold knife conization (CKC) within 9 years. Histopathological correlation analyses were carried out among the smear, colposcopic biopsy (CBx), CKC results, and total hysterectomy specimens available. Results: One hundred thirty-one cold knife cone biopsy cases were analyzed for this study. The most common pathology was cervical intraepithelial neoplasia (CIN) II–III, with a frequency of 64 (48.9%). Other conization results in order of frequency were as follows: CIN I at a rate of 29 (22.1%), Carcinoma (Ca) at 19 (14.5%), cervicitis at 14 (10.7%), and negative results at 5 (3.8%). Conclusions: CKC remains an acceptable option in the treatment of CIN and microinvasive carcinoma of the cervix, and the excellent diagnostic and therapeutic efficacy of CKC is well-known and confirmed. When properly performed, the procedure has a low risk of complications and provides an accurate histological representation of the disease process. It is also curative in most cases. Of course, excellent clinical results still require careful, long-term, and attentive follow-up.

Keywords

• Cervical intraepithelial neoplasia
• cervical smear
• cold knife conization

Kaynakça

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