Evaluation of growth and effect of metabolic control on growth velocity in children with type 1 diabetes mellitus
Öz
Purpose: One of the complications of diabetes mellitus is the disruption of growth. Evaluation of growth in type1 diabetes mellitus and the effect of metabolic control on growth velocity is aimed in this study.
Materials and methods: One hundred cases with Type1 diabetes mellitus are included and annual growth velocity, the status of metabolic control, and stage of puberties of cases are evaluated.
Results: There was no significant difference in height SDSs between at the time of diagnosis and current. Forty-three percent of the children had lower height than the genetic height potential. Evaluation of the relationship between Growthvelocity SDS and HbA1c values according to years showed a negative correlation in the third year. Evaluation of 23 cases that had attained final height presented no significant difference between height SDS at the time of diagnosis and final height SDS. Seventy-seven and a half percent of 18 cases satisfied the target height; 22.2% of cases attained a shorter final height than the target height based on evaluation with the reference to genetics. There was no difference between the metabolic controls.
Conclusions: Final height and growth velocity didn’t appear to be affected in cases with good and intermediate metabolic controls; final height and growth velocity are negatively affected in cases with poor metabolic controls.
Materials and methods: One hundred cases with Type1 diabetes mellitus are included and annual growth velocity, the status of metabolic control, and stage of puberties of cases are evaluated.
Results: There was no significant difference in height SDSs between at the time of diagnosis and current. Forty-three percent of the children had lower height than the genetic height potential. Evaluation of the relationship between Growthvelocity SDS and HbA1c values according to years showed a negative correlation in the third year. Evaluation of 23 cases that had attained final height presented no significant difference between height SDS at the time of diagnosis and final height SDS. Seventy-seven and a half percent of 18 cases satisfied the target height; 22.2% of cases attained a shorter final height than the target height based on evaluation with the reference to genetics. There was no difference between the metabolic controls.
Conclusions: Final height and growth velocity didn’t appear to be affected in cases with good and intermediate metabolic controls; final height and growth velocity are negatively affected in cases with poor metabolic controls.
Anahtar Kelimeler
Type 1 diabetes mellitus in children, growth velocity, final height
Kaynakça
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