Meme kanseri olan Türk kadın hastalarda meme dansitesinin klinik ve patolojik bulgularla ilişkileri

Yıl 2022, Cilt: 15 Sayı: 2, 309 - 317, 01.04.2022

Nihan Turhan , Dilek Yılmaz , Levent Yeşilyurt

https://doi.org/10.31362/patd.982998

Öz

Amaç: Meme kanseri, kadınlarda kansere bağlı ölüm nedenleri arasında tüm dünyada çok büyük bir tehdit oluşturmaktadır. Uzun yıllardır meme kanseri etiyolojisine yönelik çalışmalar yapılmaktadır. Memenin radyolojik dansite yoğunluğunun meme kanseri üzerinde etkili olduğunun gösterilmesi ile bu konuda çalışmalar hızlanmıştır. Yapılan çalışmalarda meme dansitesinin farklı etnik kökenli toplumlar arasında değişiklikler gösterdiği sunulmuştur. Çalışmamızda Türk uyruklu meme kanseri hastalarının meme dansiteleri ile meme kanseri ilişkisi araştırılmıştır.
Gereç ve yöntem: Çalışmamızda 01.01.2018-01.01.2021 tarihleri arasında hastanemizde tedavi edilen Türk uyruklu meme kanseri hastalarında meme dansitesi, yaş, menopoz durumu, vücut kitle indeksi ve tümörün patolojik özelikleri retrospektif olarak değerlendirilmiştir.
Bulgular: Elde edilen veriler ışığında meme dansitesinin yaş arttıkça ve post-menopozal dönemde ve vücut kitle indeksinin arttığı durumlarda istatistiksel açıdan anlamlı olarak düşük olduğu gösterilmiştir. Ancak meme dansitesi ile tümör boyutu ve patolojik belirteçler arasında anlamlı bir ilişki saptanamamıştır.
Sonuç: Meme dansitesi, meme kanseri için başta obezite durumu ve hormonal değişimler ile bireyin ömrü boyunca değişen ve modifiye edilebilen bir risk faktörüdür. Meme dansitesi yoğun hastaların tanınması, meme kanseri riskini azaltıcı önlemlerin alınması ve gereklilik halinde ek görüntüleme yöntemleri ile daha sık aralıklarla izlenmeleri gerekmektedir.

Anahtar Kelimeler

Meme kanseri, meme dansitesi, patoloji

Teşekkür

N.T. çalışmanın ana fikrini kurgulamış, D.Y verileri toplamıştır. L.Y. mamografi filmlerini, D.Y. patoloji verilerini analiz etmiştir. N.T. makalenin yazımında ana katkıyı sağlamıştır. Tüm yazarlar eleştirel geri bildirim sağlayarak ve araştırmanın, analizin ve makalenin şekillenmesine yardımcı oldular.

The relationship between breast density and clinical and pathological findings in Turkish female patients with breast cancer

Öz

Purpose: Breast cancer is one of the leading causes of cancer-related death in women all over the world. Studies on the ethiology of breast cancer have been carried out for many years. With the demonstration of the radiological breast density as a risk factor on breast cancer, studies on this subject have been accelerated. Studies have shown that breast density varies between societies with different ethnic origins. In our study, the relationship between breast density and breast cancer in Turkish breast cancer patients is investigated.
Materials and methods: In our study, breast density, age, menopausal status, body mass index and pathological features of the tumor were evaluated retrospectively in Turkish breast cancer patients treated in our hospital between 01.01.2018-01.01.2021.
Results: According to the data obtained, it has been shown that breast density is statistically significantly lower as age increases, in the post-menopausal period and as body mass index increases. However, no significant relationship was found between breast density and tumor size and pathological markers.
Conclusion: Breast density is a risk factor for breast cancer that can be changed and modified throughout the life of the individual, primarily by obesity and hormonal changes. Patients with dense breast should be identified, taken measures to reduce the risk of breast cancer and followed more frequently with additional imaging methods if necessary.

Anahtar Kelimeler

Breast cancer, breast density, pathology

Kaynakça

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