The role of coagulation mechanism in the development of acute thrombosed hemorrhoidal disease

Yıl 2023, Cilt: 16 Sayı: 2, 216 - 221, 05.04.2023

Selman ALKAN Murat ÇAKIR Alper VARMAN Mustafa SENTÜRK Omer KİSİ Ahmet TOPAL

https://doi.org/10.31362/patd.1181190

Öz

Purpose: Hemorrhoidal disease is a common benign anorectal disease. Acute thrombosis that occurs during the course of hemorrhoidal disease is a painful complication. Factors affecting its etiopathogenesis are not known definitively. The aim of this study, therefore, was to assess predisposition to coagulation during the development of the disease.
Material and methods: 30 patients with acute thrombosed hemorrhoidal disease and 30 other patients with hemorrhoidal disease but no thromboses were included in the study. Samples collected from
these patients were analyzed with thromboelastography machines. The results were compared with patients’ demographic data.
Results: No statistically significant difference was found between the groups as per age, sex, diarrhea, history of a similar attack, history of surgical treatment, spicy food consumption, fibrous food consumption, and regular exercise. The results of our study revealed that the alpha angle was smaller in patients with acute
thrombosed hemorrhoidal disease.
Conclusion Hypercoagulability does not occur in patients with acute thrombosed hemorrhoidal disease.

Anahtar Kelimeler

Hypercoagulability, thrombosed hemorrhoid, thromboelastography

Akut tromboze hemoroidal hastalığın gelişiminde pıhtılaşma mekanizmasının rolü

Öz

Amaç: Hemoroidal hastalık sık görülen benign anorektal bölge hastalığıdır. Hemoroidal hastalığın seyri sırasında oluşan akut tromboz ağrılı bir komplikasyondur. Etyopatogenezinde etkili etmenler tam bilinmiyor. Çalışmamızdaki amacımız hastalığın gelişiminde pıhtılaşmaya yatkınlığı değerlendirmektir.
Gereç ve yöntem: Akut tromboze hemoroidal hastalığı olan 30 hasta ile hemoroidal hastalığı olan ancak tromboz gelişmeyen 30 hasta çalışmaya dahil edildi. Bu hastalardan alınan numuneler tromboelastografi cihazında incelendi. Demografik verileri ile kıyaslandı.
Bulgular: Akut tromboze hemoroidal hastalığı olan hastalarda alfa açısının daha küçük olduğunu tespit ettik.
Sonuç: Akut tromboze hemoroidal hastalığı olan hastalarda hiperkoagülabilite durumu oluşmamaktadır. Ancak kanamaya yatkınlık gelişmektedir.

Anahtar Kelimeler

Hiperkoagülabilite, tromboze hemoroid, tromboelastografi, Hypercoagulability, thrombosed hemorrhoid, thromboelastography

Kaynakça

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