Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide
Öz
In this current work the conformational properties of the L-Alanyl-L-Glutamine dipeptide which was biological active dipeptide has been investigated by theoretical conformational analysis method using program which is based on Molecular Mechanic calculations in order to determine the structure function relation. The calculations on zwitterionic and neutral form of Ala-Gln which is formed side and main chain torsion angles let us to define their preferable energetically conformers. The side and main chain status of the stable conformations of Ala-Gln were acquired based on the results of the conformational analysis. By using Ramachandran maps, the global conformation, which has the lowest energy of the dipeptide, has been determined. The goal of this work was to explain structure-activity relationship by investigating the bioactive conformation of biological active peptide.
Anahtar Kelimeler
Kaynakça
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Ayrıntılar
Birincil Dil
Türkçe
Konular
-
Bölüm
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Yayımlanma Tarihi
24 Ekim 2017
Gönderilme Tarihi
13 Nisan 2017
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2017 Cilt: 21 Sayı: 3
APA
Kecel Gunduz, S., & Celık, S. (2017). Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 21(3), 836-842. https://doi.org/10.19113/sdufbed.02983
AMA
1.Kecel Gunduz S, Celık S. Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide. Süleyman Demirel Üniv. Fen Bilim. Enst. Derg. 2017;21(3):836-842. doi:10.19113/sdufbed.02983
Chicago
Kecel Gunduz, Serda, ve Sefa Celık. 2017. “Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide”. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi 21 (3): 836-42. https://doi.org/10.19113/sdufbed.02983.
EndNote
Kecel Gunduz S, Celık S (01 Aralık 2017) Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi 21 3 836–842.
IEEE
[1]S. Kecel Gunduz ve S. Celık, “Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide”, Süleyman Demirel Üniv. Fen Bilim. Enst. Derg., c. 21, sy 3, ss. 836–842, Ara. 2017, doi: 10.19113/sdufbed.02983.
ISNAD
Kecel Gunduz, Serda - Celık, Sefa. “Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide”. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi 21/3 (01 Aralık 2017): 836-842. https://doi.org/10.19113/sdufbed.02983.
JAMA
1.Kecel Gunduz S, Celık S. Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide. Süleyman Demirel Üniv. Fen Bilim. Enst. Derg. 2017;21:836–842.
MLA
Kecel Gunduz, Serda, ve Sefa Celık. “Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide”. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, c. 21, sy 3, Aralık 2017, ss. 836-42, doi:10.19113/sdufbed.02983.
Vancouver
1.Serda Kecel Gunduz, Sefa Celık. Molecular Mechanic Studies on the Zwitterionic and Neutral Conformation Stability of Biological Active Peptide. Süleyman Demirel Üniv. Fen Bilim. Enst. Derg. 01 Aralık 2017;21(3):836-42. doi:10.19113/sdufbed.02983