Yanıt Yüzey Metodolojisi Şartlarında Karabaş Otu Yağının Kompleks Koaservasyon Yöntemi İle Enkapsülasyonu

Öz

Çalışmamızda karabaş otu yağı yanıt yüzey metodolojisi (YYM) ile oluşturulan bir deney setinde kompleks koaservasyon yöntemi ile enkapsülasyon yapılmıştır. Deney seti YYM’e üç bağımsız değişken (çekirdek maddesi miktarı, surfaktan konsantrasyonu, karıştırma hızı) girilerek oluşturulmuştur. Üretilen numunelerden enkapsülasyon verimi (%EV) hesaplanmıştır. Bulunan deneysel verimler YYM’e cevap yanıtı olarak girilerek analiz edilmiştir. YYM analizi sonucunda ulaşılan model önemlidir (p<0,05), R2 değeri %99,15, uyum eksikliğinin p değeri 0,217 (p>0,05) bulunmuştur. Elde edilen verilerden YYM’e girilen üç bağımsız değişkenin cevap yanıtı olan %EV’yi etkilediği sonucuna ulaşılmıştır. Deney setinden üretilen numuneler optik mikroskop ve taramalı elektron mikroskobu (SEM) altında karakterize edilmiştir. Elde edilen görüntülerde kapsüller, büyük çoğunluğu mikron (10-6), az miktarda nano (10-9) boyutunda gözlenmiştir. Yapılan çalışmanın kullanım alanlarının geniş, ekonomik değeri yüksek olan karabaş otu yağının enkapsülasyonunda ve farklı uygulama alanlarında değerlendirilmesinde önemli bir adım olacağı düşünülmektedir.

Anahtar Kelimeler

• Karabaş otu
• Kompleks koaservasyon
• Enkapsülasyon
• Mikro teknoloji
• Nano teknoloji

Encapsulation of Karabas Herb Oil with Complex Coacervation Method in Response Surface Methodology Conditions

Öz

In our study, encapsulation was performed with complex coacervation method in an experimental set created with Karabas herb oil response surface methodology (RSM). The experiment set was created by entering three independent variables (core material amount, surfactant concentration, stirring speed) in RSM. The encapsulation efficiency (EV%) was calculated from the produced samples. The experimental efficiencies found were analyzed by entering RSM as a response response. The model reached as a result of RSM analysis was significant (p <0,05), R2 value was 99,15%, and lack-of-fit p value was found as 0,217 (p>0,05). The collected data indicated that three independent variables entered in RSM affect the response response EV%. Samples produced from the experimental set were characterized under optical microscope and scanning electron microscope (SEM). The vast majority of the images obtained were observed in micron (10-6) and a small amount of nano (10-9) in size. It is believed that the study will be an important step in the encapsulation of karabaş herb oil, which has a wide range of economic value, and different application areas.

Anahtar Kelimeler

• Karabas herb
• Complex coacervation
• Encapsulation
• Micro technology
• Nano technology

Kaynakça

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