Baicaleinin İndirekt Seramik Restorasyonların Bağlanma Kuvvetine Etkisi

Yıl 2025, Cilt: 16 Sayı: 3, 356 - 365, 22.12.2025

Nuray Zulkadir Ergin , Aslı Seçilmiş

https://doi.org/10.22312/sdusbed.1661264

Öz

Özet: Bu çalışmanın amacı, bir matriks metalloproteinaz inhibitörü olan Baicalein'in seramik simantasyonunda rezin-dentin bağlanma dayanımı üzerindeki etkisini değerlendirmektir. On altı insan mandibular yirmi yaş dişinin oklüzal minesi aşındırıldı ve cam matriks seramik (Celtra Duo) overleyler hazırlandı. Örnekler rastgele dört gruba ayrıldı. Kontrol grubu, total-etch dual-cure rezin siman (Variolink N) kullanılarak ek işlem yapılmadan simante edildi. Dimetil sülfoksit ve baicalein gruplarında asitleme işleminden sonra dentin yüzeyine ilgili gruba ait solüsyon uygulandı. Sonrasında seçilen simana ait rutin simantasyon işlemine devam edildi. Baicalein+ultrasonik aktivasyon grubunda diğer iki gruptan farklı olarak asitleme işleminden sonra baicalein solüsyonu uygulandı, 10 saniye boyunca ultrasonik aktivasyon yapıldı ve uygulanan materyallerin aynı penetrasyon derinliğine ulaşabilmesi için simantasyonun her aşamadasında ultrasonik aktivasyona devam edildi. Örnekler termal yaşlandırmaya tabi tutuldu. Örnekler kesilerek mikroçubuklar elde edildi ve mikroçekme testleri yapıldı. Bağ yüzeyi ve ön işlem görmüş oklüzal yüzey taramalı elektron mikroskobu kullanılarak görüntülendi. İstatistiksel analiz için Shapiro-Wilk testi, Kruskal-Wallis testi ve Dunn çoklu karşılaştırma testleri uygulandı. İstatistik analiz sonuçlarına göre kontrol grubunun bağlanma dayanımı değerleri diğer üç gruba oranla anlamlı derecede yüksek olduğu görüldü. Dimetil sülfoksit ve/veya baicalein solüsyonlarının kullanımı, total-etch dual-cure rezin siman için seramik ve dentine bağlanma dayanımını artırmadığı sonucuna varıldı.

Anahtar Kelimeler

MMP , Degradasyon , Mikroçekme testi

Proje Numarası

DHF.UT.21.03.

Effect of Baicalein on Bond Strength of Indirect Ceramic Restoration

Öz

Abstract: This study aimed to evaluate the effect of a matrix metalloproteinase inhibitör (Baicalein) on the resin-dentin bond strength in ceramic cementation. The occlusal enamel of sixteen human mandibular wisdom teeth was cut, and glass matrix ceramic (Celtra Duo) overlays were prepared. The samples were randomly divided into four groups. The control group was cemented without pretreatment using total-etch dual-curing resin cement (Variolink N). In the dimethyl sulfoxide and baicalein groups, the solution was applied to the dentin after acid etching. Subsequently, the standard cementation process was continued. In the baicalein and ultrasonic agitation group, unlike the other two groups, after etching, the baicalein solution was applied, ultrasonic agitation was performed for 10 seconds, and agitation was carried out at each stage. The samples underwent thermal aging. Microbars were obtained by cutting the samples, and microtensile tests were conducted. The bond surface and the pretreated occlusal surface were observed using a scanning electron microscope. Shapiro-Wilk test, Kruskal-Wallis test and Dunn's multiple comparison test were applied for statistical analysis. The bond strength values of the control group were significantly higher than those of the other three groups. The use of dimethyl sulfoxide and/or baicalein solutions did not improve the bond strength to the ceramic and dentin for the total-etch dual-cure resin cement.

Anahtar Kelimeler

MMP , Degradation , Microtensile test

Etik Beyan

The present study was reviewed and approved for research by the Medical Ethics Committee of the University of Gaziantep (protocol number 2020/383, 16.12.2020). The authors declare no conflicts of interest related to the materials tested in the present study.

Destekleyen Kurum

Scientific Research Projects Governing Unit

Proje Numarası

DHF.UT.21.03.

Teşekkür

The BAI solution used in the study was prepared in the Chemistry Department of Gaziantep University, Faculty of Arts and Science with the support of Prof. Dr. Aysegul IYIDOĞAN.

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