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Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report

Cilt: 33 Sayı: 2 29 Haziran 2026
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Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report

Öz

Adenomatoid tumors are benign mesothelial neoplasms most commonly arising in the genital tract. When the smooth muscle component predominates over the adenomatoid component, the lesion is termed a leiomyoadenomatoid tumor (LMAT), which may mimic leiomyoma or even malignancy. Accurate diagnosis is therefore essential to avoid overtreatment. We report a case of a 52-year-old woman who underwent total hysterectomy with bilateral salpingo-oophorectomy for presumed uterine leiomyoma. Histopathological and immunohistochemical evaluation revealed a leiomyoadenomatoid tumor measuring 11 cm, to the best of our knowledge, among the largest reported cases in the literature. The patient remained asymptomatic with no recurrence during a two-year follow-up. This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.

Anahtar Kelimeler

Destekleyen Kurum

This research did not receive any specific grant from funding agencies in the public, commercial, or not-forprofit sectors

Etik Beyan

Consent to Participate and Publish Written informed consent to participate and publish was obtained from the patient.

Kaynakça

  1. 1. Isotalo PA, Keeney GL, Sebo TJ, Riehle DL, Cheville JC. Adenomatoid tumor of the adrenal gland: a clinicopathologic study of five cases and review of the literature. Am J Surg Pathol. 2003;27:969–977. doi:10.1097/00000478-200307000-00012.
  2. 2. McGrath N, Aja-Okorie U, Pather S. Leiomyoadenomatoid tumor of the uterus: finding the rare in the routine. Int J Gynecol Pathol. 2022;41:573–577. doi:10.1097/PGP.0000000000000840.
  3. 3. Young RH, Silva EG, Scully RE. Ovarian and juxtaovarian adenomatoid tumors: a report of six cases. Int J Gynecol Pathol. 1991;10:364–371. doi:10.1097/00004347-199110000-00009.
  4. 4. Bahuguna G, Misra D, Malhotra V, Sinha A. Multicentric leiomyoadenomatoid tumor of the uterus: a rare and distinct morphological entity. J Obstet Gynaecol India. 2014;64(Suppl 1):152–153. doi:10.1007/s13224-014-0527-2.
  5. 5. Amre R, Constantino J, Lu S, Charney D. Pathologic quiz case: a 52-year-old woman with a uterine mass. Leiomyoadenomatoid tumor of the uterus. Arch Pathol Lab Med. 2005;129:e77– e78. doi:10.5858/2005-129-e77-PQCAYW.
  6. 6. Skinnider BF, Young RH. Infarcted adenomatoid tumor: a report of five cases of a facet of a benign neoplasm that may cause diagnostic difficul . Am J Surg Pathol. 2004;28:77–83. doi:10.1097/00000478-200401000-00008.
  7. 7. Hafiz B, Silimi MH, Felmban W. Leiomyoadenomatoid tumors of the uterus: a case report and literature review. Am J Case Rep. 2021;22:e934012. doi:10.12659/AJCR.934012.
  8. 8. Hong R, Choi DY, Choi SJ, Lim SC. Multicentric infarcted leiomyoadenomatoid tumor: a case report. Int J Clin Exp Pathol. 2009;2(1):99–103.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Kadın Hastalıkları ve Doğum

Bölüm

Olgu Sunumu

Yayımlanma Tarihi

29 Haziran 2026

Gönderilme Tarihi

21 Temmuz 2025

Kabul Tarihi

18 Mayıs 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 33 Sayı: 2

Kaynak Göster

APA
İsenlik, B. S., Ozturk Inal, Z., Han, O., Küçükosmanoğlu, İ., & İnal, H. (2026). Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report. Medical Journal of Süleyman Demirel University, 33(2), 220-223. https://doi.org/10.17343/sdutfd.1747238
AMA
1.İsenlik BS, Ozturk Inal Z, Han O, Küçükosmanoğlu İ, İnal H. Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report. SDÜ Tıp Fak Derg. 2026;33(2):220-223. doi:10.17343/sdutfd.1747238
Chicago
İsenlik, Bekir Sıtkı, Zeynep Ozturk Inal, Orkun Han, İlknur Küçükosmanoğlu, ve Hasan İnal. 2026. “Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report”. Medical Journal of Süleyman Demirel University 33 (2): 220-23. https://doi.org/10.17343/sdutfd.1747238.
EndNote
İsenlik BS, Ozturk Inal Z, Han O, Küçükosmanoğlu İ, İnal H (01 Haziran 2026) Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report. Medical Journal of Süleyman Demirel University 33 2 220–223.
IEEE
[1]B. S. İsenlik, Z. Ozturk Inal, O. Han, İ. Küçükosmanoğlu, ve H. İnal, “Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report”, SDÜ Tıp Fak Derg, c. 33, sy 2, ss. 220–223, Haz. 2026, doi: 10.17343/sdutfd.1747238.
ISNAD
İsenlik, Bekir Sıtkı - Ozturk Inal, Zeynep - Han, Orkun - Küçükosmanoğlu, İlknur - İnal, Hasan. “Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report”. Medical Journal of Süleyman Demirel University 33/2 (01 Haziran 2026): 220-223. https://doi.org/10.17343/sdutfd.1747238.
JAMA
1.İsenlik BS, Ozturk Inal Z, Han O, Küçükosmanoğlu İ, İnal H. Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report. SDÜ Tıp Fak Derg. 2026;33:220–223.
MLA
İsenlik, Bekir Sıtkı, vd. “Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report”. Medical Journal of Süleyman Demirel University, c. 33, sy 2, Haziran 2026, ss. 220-3, doi:10.17343/sdutfd.1747238.
Vancouver
1.Bekir Sıtkı İsenlik, Zeynep Ozturk Inal, Orkun Han, İlknur Küçükosmanoğlu, Hasan İnal. Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report. SDÜ Tıp Fak Derg. 01 Haziran 2026;33(2):220-3. doi:10.17343/sdutfd.1747238

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