Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome

Aydın Ece; Leyla Çolpan; Mehmet Yılmaz; Fuat Gürkan; Kenan Haspolat

doi:10.17343/sdutfd.72216

Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome

Öz

SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 1999 Haziran; 6(2) Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome Aydın Ece, Leyla Çolpan, Mehmet Emin Yılmaz, Fuat Gürkan, Kenan Haspolat Abstract The pathogenesis of idiopathic nephrotic syndrome (INS) is stili controversial. Lymphocytic dysfunction and increased cytokine prodıtction have been suggested to be pathogenetic mechanism for renal injury in childhood INS. in order to investigate the role of certain cytokines, 23 children with steroid sensitive INS, aged 2-8 years, and 29 healthy controls were included in the study. Blood samples ofpatients were taken both at remission and relapse phases of the disease. Cytokines were measured by the chemiluminescent immunometric assay. Interleukin (lL)-l/3 vvas undetectable in serum samples of ali children. Serum levels of soluble interleukin-2 receptor (sIL-2R), IL-6, IL-8, and tümör necrosis factor-alpha (TNF-a) vere signifıcantly higher in relapsing phase of INS compared to remission and controls. Signifıcant correlation wasfound between sIL-2R and 24-hour proteinuria. in conclusion, sIL-2R, IL-6, IL-8 and TNF-a may have a role in the pathogenesis of renal injury in childhood steroid sensitive INS. Key Words: Children, cytokines, nephrotic syndrome, pathogenesis

Anahtar Kelimeler

-

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Aydın Ece Bu kişi benim

Leyla Çolpan Bu kişi benim

Mehmet Yılmaz Bu kişi benim

Fuat Gürkan Bu kişi benim

Kenan Haspolat Bu kişi benim

Yayımlanma Tarihi

10 Mart 2009

Gönderilme Tarihi

9 Mart 2009

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 1999 Cilt: 6 Sayı: 2

DOI

https://doi.org/10.17343/sdutfd.72216

IZ

https://izlik.org/JA98NH96LM

Kaynak Göster

RIS / Bibtex

APA

Ece, A., Çolpan, L., Yılmaz, M., Gürkan, F., & Haspolat, K. (2009). Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome. Medical Journal of Süleyman Demirel University, 6(2). https://doi.org/10.17343/sdutfd.72216

AMA

1.Ece A, Çolpan L, Yılmaz M, Gürkan F, Haspolat K. Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome. SDÜ Tıp Fak Derg. 2009;6(2). doi:10.17343/sdutfd.72216

Chicago

Ece, Aydın, Leyla Çolpan, Mehmet Yılmaz, Fuat Gürkan, ve Kenan Haspolat. 2009. “Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome”. Medical Journal of Süleyman Demirel University 6 (2). https://doi.org/10.17343/sdutfd.72216.

EndNote

Ece A, Çolpan L, Yılmaz M, Gürkan F, Haspolat K (01 Mart 2009) Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome. Medical Journal of Süleyman Demirel University 6 2

IEEE

[1]A. Ece, L. Çolpan, M. Yılmaz, F. Gürkan, ve K. Haspolat, “Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome”, SDÜ Tıp Fak Derg, c. 6, sy 2, Mar. 2009, doi: 10.17343/sdutfd.72216.

ISNAD

Ece, Aydın - Çolpan, Leyla - Yılmaz, Mehmet - Gürkan, Fuat - Haspolat, Kenan. “Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome”. Medical Journal of Süleyman Demirel University 6/2 (01 Mart 2009). https://doi.org/10.17343/sdutfd.72216.

JAMA

1.Ece A, Çolpan L, Yılmaz M, Gürkan F, Haspolat K. Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome. SDÜ Tıp Fak Derg. 2009;6. doi:10.17343/sdutfd.72216.

MLA

Ece, Aydın, vd. “Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome”. Medical Journal of Süleyman Demirel University, c. 6, sy 2, Mart 2009, doi:10.17343/sdutfd.72216.

Vancouver

1.Aydın Ece, Leyla Çolpan, Mehmet Yılmaz, Fuat Gürkan, Kenan Haspolat. Serum Levels of Interleukin (IL)-lp, sIL-2R, IL-6, IL-8 and TNF-a in Chüdren with idiopatine Nephrotic Syndrome. SDÜ Tıp Fak Derg. 01 Mart 2009;6(2). doi:10.17343/sdutfd.72216