Cilt: 32 Sayı: 2 , 19.06.2025

Yıl: 2025

Araştırma Makalesi

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Prof. Dr. Ali Ekrem ÜNAL Bir kuruma bağlı değildir
Genel Cerrahi
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Dr. Öğr. Üyesi Buket GÜNGÖR CANAKKALE ONSEKIZ MART UNIVERSITY, ÇANAKKALE HEALTH ACADEMY
Klinik Tıp Bilimleri (Diğer), Sağlık Bilimleri
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Prof. Dr. Evrim ERDEMOGLU SULEYMAN DEMIREL UNIVERSITY, SCHOOL OF MEDICINE
Jinekolojik Onkoloji Cerrahisi, Kadın Hastalıkları ve Doğum
Mustafa Nazıroğlu
Prof. Dr. Mustafa NAZIROĞLU SULEYMAN DEMIREL UNIVERSITY, FACULTY OF MEDICINE, MEDICINE PR. Web

Professor Mustafa Nazıroğlu has graduated from Veterinary Faculty, Fırat University at 1991 and he received his PhD (Physiology) in Fırat University during the period of 1992-1996. He obtained second PhD at 2018 on Neuroscience in Suleyman Demirel University (SDU). Currently, he is working as Head of Department of Biophysics and Neuroscience in SDU, Medical Faculty. He has successfully completed his administrative responsibilities as Head of departments, Head of Congress organization committee, director of Neuroscience Research Centre (NOROBAM) in SDU. As chair of congress, he organized 1st, 2nd, 3rd, 4th, 5th, 6th, 7th and 8th biennale International World Congress of Oxidative Stress, Calcium Signalling and TRP Channels between 2006 and 2020, Isparta, Turkey. (https://2023.cmos.org.tr/). He also organized also 1st (2015), 2nd (2017), 3rd (2018), 4th (2019), 5th (2020), 6th (2021), 7th (2022), 8th (2023), and 9th (2024) (http://2024.brs.org.tr/). International Brain Research school. He served in organization committee of TEMA-14 Congress (2011), Hubei, Chine. Professor Nazıroğlu is serving as an editorial member of several reputed journals like ‘Biological Trace Element Research’, ‘Journal of Cellular Neuroscience and Oxidative Stress’, ‘Scientific Report (Nature publishing)’, ‘Frontiers in Physiology’ and ‘Current Neuropharmacology (Guest Editor)’. He is also reviewing editor in Frontiers in Membrane Physiology and Biophysics. He has been a lead speaker at drug discovery, apoptosis, calcium signaling and ion (TRP) channels conferences and other prestigious events worldwide and is a member of several expert advisory panels. He authored 274 international research and 19 review articles and 11504 citations in SCI-Thompson/Scopus and 6 international book chapters (Scopus H factor is 58). He was member of Turkish Physiological Society and Japanese Neuroscience Society. He has honored as NATO Research Fellowship, Martin-Luther University, Halle-Saale, Germany, (1999-2000), ‘Young Investigative Scientist Award (2001), UC-Berkeley, USA, Alexander von Humboldt (AvH) Research fellowship owner (June 2003-September 2005), Medical Faculty, RWTH-Aachen, Germany, Encouragement Award of Scientific and Tech. Res. Council (TUBITAK), Ankara, Turkey (2006), Howard Hudges Medical Institute (USA) support (2009), Khwarizmi International Award-IROST-Iran (2012), Visiting Professor in Leicester University, Leicester-UK (June-September 2010), Visiting Professor in Weil Cornell Medical College in Doha-Qatar (June-September 2013), Scientific Research Award of Turkish Neurosurgery Society (2016), and Travel Award of Japan Neuroscience Society (July, Tokyo-2017), Visiting Professor in NIPS, Okazaki, Japan (July-October, 2017).

Sinirbilim, Sinirbilim (Diğer), Tıbbi Fizyoloji, Biyofizik
Nilgün Gürbüz
Prof. Dr. Nilgün GÜRBÜZ SÜLEYMAN DEMİREL ÜNİVERSİTESİ, TIP FAKÜLTESİ
Sinyal İletimi, Kanser Biyolojisi, Tıbbi Biyokimya ve Metabolomik
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Dr. Öğr. Üyesi Oruç Numan GÖKÇE ÇANAKKALE ONSEKİZ MART ÜNİVERSİTESİ, TIP FAKÜLTESİ
Genel Cerrahi
Sabriye Ercan
Prof. Dr. Sabriye ERCAN Suleyman Demirel University, Faculty of Medicine
Spor ve Egzersiz Beslenmesi, Spor Hekimliği, Fiziksel Aktivite ve Sağlık
Vehbi Atahan Toğay
Doç. Dr. Vehbi Atahan TOĞAY Süleyman Demirel University Web
Kanser Biyolojisi, Genotoksisite ve Sitotoksisite, Gen İfadesi
Özlem Çoşkun
Doç. Dr. Özlem ÇOŞKUN Bir kuruma bağlı değildir
Hücresel Etkileşimler , Hayvan Hücresi ve Moleküler Biyoloji, Biyofizik, Sağlık Bilimleri

Med J SDU is an international, scientific, open access, online/print journal that follows independent, unbiased, and double-blind peer-review principles.

Med J SDU publishes research in the health sciences, including original clinical and experimental studies, reviews of current topics, case reports, editorial comments, and letters to the editor. The language of the journal is English.

About Med J SDU
Medical Journal of Süleyman Demirel University (Med J SDU) is published quarterly in March, June, September and December. Med J SDU is an international, scientific, open access, online/print journal that follows independent, unbiased, and double-blind peer-review principles.
Med J SDU publishes research in the health sciences, including original clinical and experimental studies, reviews of current topics, case reports, editorial comments, and letters to the editor. The language of the journal is English.
Med J SDU is indexing in both international (EBSCO) and national (TRDizin) indexes.
There is no charges for publishing or publication process. No copyright price are payable to the authors or other third parties for the articles published in the journal. Med J SDU has adopted the policy of providing open access with the publication. Authors’ credentials and e-mail addresses are in no way used for other purposes.
The editorial and publication processes of the journal are shaped in accordance with the guidelines of the International Council of Medical Journal Editors (ICMJE). The journal conforms to the Principles of Transparency and Best Practice in Scholarly Publishing (doaj.org/bestpractice).
Originality, high scientific quality and citation potential are the most important criteria for a manuscript to be accepted for publication. Manuscripts submitted for evaluation should not have been previously presented or already published in an electronic or printed medium. Manuscripts that have been presented in a meeting should be submitted with detailed information on the organization, including the name, date, and location of the organization.

Ethical Principles

An approval of research protocols by the Ethics Committee in accordance with international agreements (World Medical Association Declaration of Helsinki “Ethical Principles for Medical Research Involving Human Subjects,” amended in October 2013, www.wma.net) is required for experimental, clinical, and drug studies and for some case reports. Ethics committee approvals or an equivalent official documents must be uploaded into the dergipark system.
• For manuscripts concerning experimental researches on humans, a “Written Informed Consent to Participate and Publish” statement should included in the text.
• Written Informed Consent to Participate Publish statement and Ethics Committee approval details (name of the committee, date and number) should included in the Materials and Methods section and in the end of the article (before references) with separate sub-headings.

• It is the authors responsibility to carefully protect the patients anonymity. For photographs that may reveal the identity of the patients, releases signed by the patient or their legal representative should be enclosed.
• For studies carried out on animals, the measures taken to prevent pain and suffering of the animals should be stated clearly. Ethics Committee approval details (name of the committee, date and number) should included in the Materials and Methods section and in the end of the article (before references) with separate sub-headings.

All submissions are screened by similarity detection software (Turnitin, iThenticate, and Intihal.net) and the similarity limitation is 25%. The Editorial Board of the journal handles all appeal and complaint cases within the scope of Committee on Publication Ethics (COPE) guidelines. In such cases, authors should get in direct contact with the editorial office regarding their appeals and complaints. When needed, an ombudsperson may be assigned to resolve cases that cannot be resolved internally. The Editor in Chief is the final authority in the decision-making process for all appeals and complaints.

When submitting a manuscript to Med J SDU, authors accept to assign the copyright of their manuscript to the journal. If rejected for publication, the copyright of the manuscript is considered to be assign back to the authors. Each submission must be submitted in accordance with the journal template (available for download at: https://dergipark.org.tr/tr/download/journal-file/24521), together with a Copyright Transfer Form (available for download at: https://dergipark.org.tr/tr/download/journal-file/22117). Mandatory documents to be sent can be found at https://dergipark.org.tr/tr/pub/sdutfd.
When using previously published content, including figures, tables, or any other material in both print and electronic formats, authors must obtain permission from the copyright holder. Legal, financial and criminal liabilities in this regard belong to the author(s). Statements or opinions expressed in the manuscripts published in Med J SDU reflect the views of the author(s) and not the opinions of the editors, the editorial board, or the publisher; the editors, the editorial board, and the publisher disclaim any responsibility or liability for such materials. The final responsibility in regard to the published content rests with the authors. Revisions should submit within 15 days in pre-review stage and in 30 days in review stage. Otherwise manuscripts will be rejected.

Manuscript Preparation

Manuscripts can only be submitted through the journal’s online manuscript submission and evaluation system, available at https://dergipark.org.tr/tr/pub/sdutfd. Manuscripts submitted via any other medium will not be evaluated. Manuscripts submitted to the journal will first go through a technical evaluation process where the editorial office staff will ensure that the manuscript has been prepared and submitted in accordance with the journal’s guidelines. Submissions that do not conform to the journal’s guidelines will be returned to the submitting author with technical correction requests. The editor reserves the right to reject manuscripts that do not comply with the above-mentioned requirements. Corrections may be done without changing the main text. The editor reserves the right to reject the articles that do not meet the required conditions.

Authors are required to submit the following:

• Copyright Transfer Form (Authors must use journal template)
• Title Page (Authors must use journal template, must include title of manuscript, running title, authors’ name, title and institution, corresponding author’s contact information, ORCID addresses, name of the organization supporting the research and ethical approvals)
• Main document (It should be prepared according to the journal template and should include a sectioned abstract; Full text file must also include tables and figures with legends alongside separate table and figure files, must be suitable for double blind review process. ).
• Figures (If applicable, Jpeg/png format, at least 300 DPI, high resolution, up to 6 figures)
• Tables (If applicable, Microsoft Word format, up to 6 table, Each table should not exceed one page)
• Ethical Approvals (If applicable)
• Author Contributions (according to CRediT, please see Template, Authors must use journal template)
• Plagiarism Report (The plagiarism report uploaded by the authors must be obtained from Turnitin, iThenticate, and Intihal.net, and the similarity rate must be below 25%.)
• Language Editing Certificate (Certificate should be obtained from an institution or corporation providing this service or from a person whose main business is language services such as a sworn translator)

Preparation of the Main Document

The articles should be written with double-spaced in 12 pt, Times New Roman character and at least 2 cm from all edges of each page. The main text should not contain any information about the authors’ names and affiliations. Original articles should have a structured abstract (Objective, Material and Methods, Results, Conclusion, Keywords). For case reports and reviews, the structured abstract is not used. Limit the abstract to 300 words. References, tables and citations should not be used in an abstract. Authors must include relevant keywords (3-5) on the line following the end of the abstract. All acronyms and abbreviations used in the manuscript should be defined at first use, both in the abstract and in the main text. The abbreviation should be provided in parentheses following the definition. When a drug, product, hardware, or software program is mentioned within the main text, product information, including the name of the product, the producer of the product, and city and the country of the company, should be provided in parentheses.

All references, tables, and figures should be referred to within the main text, and they should be numbered consecutively. The symbols used must be in nomenclature standards.

Original Research The manuscript should be no longer than 4,000 words and include no more than 40 references. The following subheadings should be included:

• Title
• Abstract
• Keywords
• Introduction
• Material and Methods
• Results
• Discussion
• Conclusions
• Statements (Please See: Template)
• References
• Figure and Table Legends (if necessary)

Case Reports The manuscript should be no longer than 2,000 words and include no more than 20 references. The following subheadings should be included:

• Title
• Abstract
• Keywords
• Introduction
• Case Presentation
• Discussion and Conclusion
• Statements (Please See: Template)
• References
• Figure and Table Legends (if necessary)

Reviews The manuscript should be no longer than 6,000 words and include no more than 80 references. The following subheadings should be included:
• Title
• Abstract
• Keywords
• Main text
• Conclusion
• Statements (Please See: Template)
• References
• Figure and Table Legends (if necessary)

Letter to Editor The manuscript should be no longer than 1,000 words and include no more than 10 references. The following subheadings should be included:

• Title
• Abstract
• Keywords
• Letter to Editor
• Statements (Please See: Template)
• References
• Figure and Table Legends (if necessary)

Preparation of the Figures and Tables
• Up to 6 Figures, graphics, or photographs can be submitted. Separate files (in JPEG format) should be submitted through the submission system and should not be embedded in a Word document. The minimum resolution of each submitted figure should be 300 DPI. Figures should be in high resolution so that the printed version can be read easily.
• Figures with legends should also be listed at main document for review.
• Information or illustrations must not permit identification of patients, and written informed consent for publication must be sought for any photograph.
• Up to 6 tables can be submitted. Each table should not exceed one page. Tables should be listed at main document for review.
• All tables and figures should be numbered consecutively.

References
All references should be numbered consecutively in Vancouver style. If more than two consecutive resources are used, only the first and last source numbers should be specified (for example; 2-6). Journal titles should be abbreviated in accordance with the journal abbreviations in Index Medicus. When there are 3 or fewer authors, all authors should be listed. If there are 4 or more authors, the first 3 authors should be listed followed by “et al.” The reference styles for different types of publications are presented in the following examples:

For journals;
Neville K, Bromberg A, Bromberg S, el al. The third epidemic multidrug resistant tuberculosis. Chest 1994;1(4):45-8. 555

For books;
Sweetman SC. Martindale the Complete Drug Reference. 34th ed. London: Pharmaceutical Press; 2005.

For book section;
Collins P. Embryology and development, Neonatal anatomy and growth. In: Williams PL, Bannister LH, Berry MM, Collins P, Dyson M, Dussek JE, Ferguson MWJ. Gray’s Anatomy (38th Ed) London, Churchill Livingstone, 1995; 91-342.

For website;
Gaudin S. How moon landing changed technology history [Internet]. Computerworld UK. 2009 [cited 15 June 2014]. Available from: http://www.computerworlduk.com/in-depth/it-business/2387/how-moon-landing-changed-technology-history/

For conference proceeding;
Brom A. Robotics and Mechatronics. Symposium on Robotics, Mechatronics and Animatronics in the Creative and Entertainment Industries and Arts. SSAISB 2005 Convention. University of Hertfordshire, Hatfield, UK; 2005.

For Thesis;
Ercan S. Venöz yetmezlikli hastalarda kalf kası egzersizlerinin venöz fonksiyona ve kas gücüne etkisi. Suleyman Demirel University Faculty of Medicine Sports Medicine Department Thesis. Isparta: Suleyman Demirel University. 2016.


Retraction or Reject
Manuscript Retraction: Authors may withdraw their manuscript from the journal with a written declaration with detailed reason only before DOI assigned. If a DOI has been assigned to the article, it can no longer be withdrawn by the authors.

Manuscript Reject: Editors have the authority to reject articles at any stage of the article process.

After Acceptance
If the manuscript is accepted, the acceptance letter and the last version of manuscript are sent to corresponding author through submission system. The journal board is authorized to decide in which volume of the accepted article will be printed. Authors may publish their articles on their personal or corporate websites with the appropriate cite and library rules after publication.

An approval of research protocols by the Ethics Committee in accordance with international agreements (World Medical Association Declaration of Helsinki “Ethical Principles for Medical Research Involving Human Subjects,” amended in October 2013, www.wma.net) is required for experimental, clinical, and drug studies and for some case reports. Ethics committee approvals or an equivalent official documents must be uploaded into the dergipark system.
• For manuscripts concerning experimental researches on humans, a “Written Informed Consent to Participate and Publish” statement should included in the text.
• Written Informed Consent to Participate Publish statement and Ethics Committee approval details (name of the committee, date and number) should included in the Materials and Methods section and in the end of the article (before references) with separate sub-headings.
• It is the authors responsibility to carefully protect the patients anonymity. For photographs that may reveal the identity of the patients, releases signed by the patient or their legal representative should be enclosed.
• For studies carried out on animals, the measures taken to prevent pain and suffering of the animals should be stated clearly. Ethics Committee approval details (name of the committee, date and number) should included in the Materials and Methods section and in the end of the article (before references) with separate sub-headings.

All submissions are screened by a similarity detection software (iThenticate) and the similarity limitation is 25%. The Editorial Board of the journal handles all appeal and complaint cases within the scope of Committee on Publication Ethics (COPE) guidelines. In such cases, authors should get in direct contact with the editorial office regarding their appeals and complaints. When needed, an ombudsperson may be assigned to resolve cases that cannot be resolved internally. The Editor in Chief is the final authority in the decision-making process for all appeals and complaints.

When submitting a manuscript to Med J SDU, authors accept to assign the copyright of their manuscript to the journal. If rejected for publication, the copyright of the manuscript is considered to be assign back to the authors. Each submission must be submitted in accordance with the journal template (available for download at: https://dergipark.org.tr/tr/download/journal-file/24521), together with a Copyright Transfer Form (available for download at: https://dergipark.org.tr/tr/download/journal-file/22117). Mandatory documents to be sent can be found at https://dergipark.org.tr/tr/pub/sdutfd.
When using previously published content, including figures, tables, or any other material in both print and electronic formats, authors must obtain permission from the copyright holder. Legal, financial and criminal liabilities in this regard belong to the author(s). Statements or opinions expressed in the manuscripts published in Med J SDU reflect the views of the author(s) and not the opinions of the editors, the editorial board, or the publisher; the editors, the editorial board, and the publisher disclaim any responsibility or liability for such materials. The final responsibility in regard to the published content rests with the authors. Revisions should submit within 15 days in pre-review stage and in 30 days in review stage. Otherwise manuscripts will be rejected

There is no charges for publishing or publication process. No copyright price are payable to the authors or other third parties for the articles published in the journal.

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Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi/Medical Journal of Süleyman Demirel University is licensed under Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International.