Use of Eye-Tracking Technology in Obsessive Compulsive Disorder

Öz

Obsessive-compulsive disorder (OCD) is characterized by obsessions and compulsions that limit functionality and cause significant problems in individuals' work, social, and family lives. In addition to psychological and physical symptoms, OCD also causes impairments in cognitive functions. The methods used in research to understand the underlying causes of these impairments and to develop appropriate treatment approaches have evolved with technological advancements in the last years. One of the methods that has gained popularity in recent years is eye-tracking technology, which is considered an effective tool for examining cognitive functions (attention, response inhibition, visuospatial abilities etc.). Eye-tracking technology measures the position, movements, and changes in the pupil of the eye. This study reviews the current literature on the use of eye-tracking technology in OCD. It includes 14 studies that used eye-tracking method to assess various cognitive functions in individuals with OCD. The findings suggest that eye-tracking technology can be effective in overcoming the challenges posed by the heterogeneous nature of OCD, provides more objective data, and supports findings from traditional neuropsychological tests.

Anahtar Kelimeler

• Obsessive-Compulsive Disorder
• Eye-Tracking Technology
• Eye Movements
• Cognitive Functions

Obsesif Kompulsif Bozuklukta Göz-İzleme Teknolojisi Kullanımı

Öz

Obsesif-kompulsif bozukluk (OKB), bireylerin iş, sosyal ve aile yaşantılarında ciddi problemlere yol açan, işlevselliklerini sınırlayan obsesyonlar ve kompulsiyonlarla karakterize edilen bir bozukluktur. OKB, psikolojik ve bedensel semptomlara ek olarak bilişsel işlevlerde de bozulmalara neden olabilmektedir. Bu bozuklukların temel nedenlerini anlamak ve uygun tedavi yöntemleri geliştirmek amacıyla kullanılan araştırma yöntemleri, teknolojinin ilerlemesiyle birlikte çeşitlenmektedir. Son yıllarda bilişsel işlevleri (dikkat, tepki ketleme, görsel-uzamsal yetenekler gibi ) incelemede etkili bir araç olarak görülen göz-izleme teknolojisi bu alanda giderek yaygınlaşmaktadır. Göz-izleme teknolojisi, göz konumu, hareketleri ve göz bebeği değişimlerini ölçme yeteneğine sahiptir. Bu çalışma, OKB’de göz-izleme yönteminin kullanımını ele alan güncel literatürdeki araştırmaları incelemektedir. Araştırmada, OKB’de farklı bilişsel işlevlerin göz-izleme cihazı ile ölçümlendiği 14 makale değerlendirilmiştir. Sonuçlar, göz-izleme teknolojisinin OKB’nin heterojen yapısına bağlı araştırma zorluklarını aşmada etkili olabileceğini, daha objektif veriler sağladığını ve geleneksel nöropsikolojik testlerle elde edilen bulguları desteklediğini göstermektedir.

Anahtar Kelimeler

• Obsesif-Kompulsif Bozukluk
• Göz-İzleme Teknolojisi
• Göz Hareketleri
• Bilişsel İşlevler

Kaynakça

1. Abramovitch, A., & Cooperman, A. (2015). The cognitive neuropsychology of obsessive-compulsive disorder: A critical review. Journal of Obsessive-Compulsive and Related Disorders, 5, 24-36.
2. Armstrong, T., Olatunji, B. O., Sarawgi, S., & Simmons, C. (2010). Orienting and maintenance of gaze in contamination fear: Biases for disgust and fear cues. Behaviour research and therapy, 48(5), 402-408.
3. American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (DSM5). 5th ed. American Psychiatric Association, Washington.
4. Aydın, P. Ç., & Öyekçin, D. G. (2013). Obsesif kompulsif bozuklukta bilişsel işlevler. Türk Psikiyatri Dergisi, 24(4).
5. Basel, D., & Lazarov, A. (2023). Reward functioning from an attentional perspective and obsessive-compulsive symptoms-an eye-tracking study. CNS spectrums, 28(5), 597-605.
6. Basel, D., & Lazarov, A. (2024). A sight for sore eyes? Attention allocation to obsession-provoking stimuli and stimuli reflecting compulsion completion. Motivation and Emotion, 48(1), 51-65.
7. Basel, D., Magen , M., & Lazarov, A. (2023). Increased attention allocation to stimuli reflecting end-states of compulsive behaviors among obsessive compulsive individuals. Scientific Reports, 13(1), 12190. doi:https://doi.org/10.1038/s41598-023-39459-x
8. Bradley, M. C., Hanna, D., Wilson, P., Scott, G., Quinn, P., & Dyer, K. F. (2016). Obsessive–compulsive symptoms and attentional bias: An eye-tracking methodology. Journal of behavior therapy and experimental psychiatry, 50, 303-308.

9. Burdick, K. E., Robinson, D. G., Malhotra, A. K., & Szeszko, P. R. (2008). Neurocognitive profile analysis in obsessive-compulsive disorder. Journal of the International Neuropsychological Society, 14(4), 640-645. doi:10.1017/S1355617708080727
10. Choi, S. A., & Lee, J.-H. (2015). The effect of enhanced responsibility on attentional bias in obsessive–compulsive checkers. Journal of Obsessive-Compulsive and Related Disorders, 6, 27-32.
11. Cludius, B., Wenzlaf, F., Briken, P., & Wittekind, C. E. (2019). Attentional biases of vigilance and maintenance in obsessive-compulsive disorder: an eye-tracking study. Journal of Obsessive-Compulsive and Related Disorders, 20, 30-38.
12. Ekin, M., Koçoglu, K., Boz, H. E., Akkoyun, M., Tüfekci, I. Y., Cesim, E., . . . Akdal, G. (2023). Antisaccade and memory-guided saccade in individuals at ultra-high-risk for bipolar disorder. Journal of Affective Disorders, 339, 965-972. Güneş, E. (2004). Dikkat Mekanizmaları. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 57(2).
13. Hall, K. A., Stamatis, C. A., Shaw, A. M., & Timpano, K. R. (2019). Are hoarding symptoms associated with interpersonally relevant attentional biases? A preliminary investigation. Journal of Obsessive-Compulsive and Related Disorders, 22, 100449.
14. Hirschtritt, M. E., Bloch, M. H., & Mathews, C. A. (2017). Obsessive-compulsive disorder: advances in diagnosis and treatment. Jama, 317(13), 1358-1367.
15. Hu, Y., Lıao, R., Chen, W., Kong, X., Lıu, J., Maguıre, P., . . . Wang, D. (2020). Investigating behavior inhibition in obsessive‐compulsive disorder: Evidence from eye movements. Scandinavian Journal of Psychology, 61(5), 634-641.
16. Karslıoğlu, E. H., & Yüksel, N. (2007). Obsesif kompulsif bozukluğun nörobiyolojisi. Klinik Psikiyatri, 10(3), 3-13.
17. Khayrullina, G., Panfilova, E., & Martynova, O. (2023). Increased error rate and delayed response to negative emotional stimuli in antisaccade task in obsessive-compulsive disorder. International Journal of Psychophysiology, 192, 62-71.
18. Kim, M., Shin, W., Lee, T. H., Kim, T., Hwang, W. J., & Kwon, J. S. (2021). Eye movement as a biomarker of impaired organizational strategies during visual memory encoding in obsessive–compulsive disorder. Scientific Reports, 11(1), 18402.
19. Kimble, M. O., Fleming, K., Bandy, C., Kim, J., & Zambetti, A. (2010). Eye tracking and visual attention to threating stimuli in veterans of the Iraq war. Journal of anxiety disorders, 24(3), 293-299.
20. Kohli, A., Rana, D. K., Gupta, N., & Kulhara, P. (2015). Neuropsychological assessment in obsessive-compulsive disorder. Indian journal of psychological medicine, 37(2), 205-211.
21. Narayanaswamy, J. C., Subramaniam, A., Bose, A., Agarwal, S. M., Kalmady, S. V., Jose, D., . . . Reddy, Y. J. (2021). Antisaccade task performance in obsessive-compulsive disorder and its clinical correlates. Asian Journal of Psychiatry, 57, 102508.
22. Popa, L., Selejan, O., Scott, A., Mures¸anu, D. F., Balea, M., & Rafila, A. (2015). Reading beyond the glance: eye tracking in neurosciences. Neurological Sciences, 36(5), 683-688. doi:10.1007/s10072-015-2076-6
23. Punde, P. A., Jadhav, M. E., & Manz, R. R. (2017). A study of Eye Tracking Technology and its applications. In 2017 1st International Conference on Intelligent Systems and Information Management (ICISIM) (s. 86-90). IEEE.
24. Sassano-Higgins, S. A., & Pato, M. T. (2015). Obsessive-compulsive disorder: diagnosis, epidemiology, etiology, and treatment. Focus, 13(2), 129-141.
25. Stewart, S. E. (2016). Obsessive-compulsive disorder. Psychiatric Neurotherapeutics: Contemporary Surgical and Device-Based Treatments, 23-50.
26. Suhas, S., & Rao, N. P. (2019). Neurocognitive deficits in obsessive–compulsive disorder: A selective review. Indian journal of psychiatry, 61(1), 30-36.
27. Tümkaya, S., Yıldız, T., Uğurlu, T. T., & Ateşçi, F. Ç. (2020). Obsesif Kompulsif Bozukluk Hastalarının İnsanların Bakış İşaretine Spontan Olarak Odaklanmaları Bozuktur: Bir Göz İzleme Çalışması. Türk Psikiyatri Dergisi, 31 (3), 168-173.
28. Thierfelder, A., Severitt, B., Klein C. S., Alt, A. K., Hollmann, K., Bulling A., Ilg, W. (2024). Gaze Behaviour in Adolescents with Obsessive-Compulsive Disorder During Exposure Within Cognitive-Behavioural Therapy. In: Salvi, D., Van Gorp, P., Shah, S.A. (eds) International Conference on Pervasive Computing Technologies for Healthcare , vol 572, 3-17. Springer, Cham. https://doi.org/10.1007/978-3-031-59717- 6_1
29. Waters, A. J., Carter, B. L., Robinson, J. D., Wetter, D. W., Lam, C. Y., Kerst, W., & Cinciripini, P. M. (2009). Attentional bias is associated with incentive-related physiological and subjective measures. Experimental and Clinical Psychopharmacology, 17(4), 247-257. https://doi.org/10.1037/a0016658