Optik Nörit Takibinde Nöromiyelitis Optika

Yıl 2017, Cilt: 11 Sayı: 1, 59 - 61, 01.04.2017

Zeynep Selen Karalök Birce Dilge Taşkın Alev Güven Emine Akkuzu Cahide Yılmaz

https://izlik.org/JA28FU38ML

Öz

Nöromiyelitis optika (NMO), optik sinirler ve spinal kordu hedef alan santral sinir sisteminin nadir görülen demiyelinizan hastalıklarından biridir. Tanısı, Wingerchuck kritelerine göre konulur. Biz de yedi yıl sonra çok sayıda optik nörit atağı geçirdikten sonra NMO tanısı alan 16 yaşında erkek bir hastayı sunduk. NMO; optik nörit ile başvuran olgularda akılda tutulması gereken bir tanıdır.

Anahtar Kelimeler

Aquaporin 4 protein , Nöromyelitis optika , Optik nörit

Optik Nörit Takibinde Nöromiyelitis Optika Neuromyelitis Optica in the Follow-Up of Optic Neuritis

https://izlik.org/JA28FU38ML

Öz

Neuromyelitis optica (NMO), is a rare demyelinating disorder of the central nervous system that preferentially targets the optic nerves and the spinal cord. The diagnosis is made using Wingerchuck’s criteria. We report the case of a 16-yearold male patient who received an NMO diagnosis seven years later, after several attacks of optic neuritis. The NMO diagnosis should be kept in mind in patients presenting with optic neuritis

Anahtar Kelimeler

Aquaporin 4 protein , Neuromyelitis optica , Optic neuritis

Kaynakça

• Toosy AT, Mason DF, Miller DH. Optic neuritis. Lancet Neurol 2014;13:83-9.
• Tillema JM, Mckeon A. The spectrum of neuromyelitis optica (NMO) in childhood. J Child Neurol 2012;27:1437-7.
• Wingerchuck DM. Diagnosis and treatment of neuromyelitis optica. Neurologist 2007;13:2-11.
• McKeon A, Lennon VA, Lotze T, Tenenbaum S, Ness JM, Rensel M, et al. CNS aquaporin-4 autoimmunity in children. Neurology 2008;71:93-100.
• Banwell B, Tenembaum S, Lennon VA, Ursell E, Kennedy J, Bar-Or A, et al. Neuromyelitis optica-IgG childhood inflammatory demyelinating CNS disorders. Neurology 2008;70:344-52.
• Jacob A, Matiello M, Wingerchuck DM. Neuromyelitis optica: Changing concepts. J Neuroimmunol 2007;187:126-38.
• Wingerchuck DM, Lucchinetti CF. Comparative immunopathoge- nesis of acute disseminated encephalomyelitis, neuromyelitis opti- ca, and multiple sclerosis. Curr Opin Neurol 2007;20:343-50.
• Boiko A, Vorobeychik G, Paty D, Devonshire, Sadovnick D. Early onset multiple sclerosis: A longitudinal study. Neurology 2002;59: 1006–10.
• Banwell B, Ghezzi A, Bar-Or A, Mikaeloff Y, Tardieu M. Multiple sclerosis in children: Clinical diagnosis, therapeutic strategies, and future directions. Lancet Neurol 2007;6:887–902.
• Uzawa A, Mori M, Muto M, Masuda S, Kuwabara S. When is neuromyelitis optica diagnosed after disease onset? J Neurol 2012;259:1600-5.
• Kim SH, Huh SY, Lee SJ, Joung A, Kim HJ. A 5-year follow-up rituximab in patients with neuromyelitis optica spectrum disorders. JAMA Neurol 2013;70:1110-7.
• Kim SH, Kim W, Li XF, Jung IJ, Kim HJ. Does interferon beta treatment exacerbate neuromyelitis optica spectrum disorders? Mult Scler 2012;18:1480-3.