SYNTHESIS OF 2-FLUOROBENZOYL THIOUREA DERIVATIVES

Şule Erol Günal

doi:10.55071/ticaretfbd.1364818

Araştırma Makalesi

2-FLOROBENZOİL TİYOÜRE TÜREVLERİNİN SENTEZİ

Yıl 2023, Cilt: 22 Sayı: 44, 417 - 424, 31.12.2023

Şule Erol Günal

https://doi.org/10.55071/ticaretfbd.1364818

Cited By: 2

Öz

Flor içeren bileşikler ilaç geliştirmede önemli bir rol oynar çünkü flor atomu, ilaç tasarımı için önemli olan özellikleri önemli ölçüde etkileyen yüksek elektronegatifliği nedeniyle benzersiz kimyasal özelliklere sahiptir. Bu çalışmada, 2-florobenzoil klorürün amonyum tiyosiyanat ile reaksiyonu sonucu elde edilen 2-florobenzoil izotiyosiyanatın uygun anilin türevleri ile reaksiyonu sonucu bir dizi 2-florobenzoil tiyoüre türevi sentezlendi. Benzoil tiyoüre yapıları IR, 1H ve 13C NMR spektroskopisi ile doğrulandı.

Anahtar Kelimeler

Tiyoüreler , Benzoil tiyoüreler , florlu bileşikler

Kaynakça

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