Effects of rheumatoid arthritis on hearing and vestibular system

Öz

Rheumatoid arthritis (RA) is an autoimmune disease which is characterized by the passage of primarily CD4 (+) T cells and monocytes into the intravenous inflamed synovial tissue and synovial fluid. The effect of RA on hearing is an issue being discussed. Hearing loss can be conductive, sensorineural or mixed. Conductive hearing loss occurs with the involvement of tympano-ossicular system. Sensorineural hearing loss may have arisen due to the neuritis, vasculitis or ototoxic effects of the drugs used during the treatment. In addition to hearing disorders, RA may also cause vestibular system disorders. Pathophysiology of the vestibular disorders are still unclear. In this review, the effects of RA on hearing and vestibular system were presented with the literature survey.

Key words: Rheumatoid artritis, hearing, conductive hearing loss, Sensorineural hearing loss, vasculitis, vestibular disorder

Anahtar Kelimeler

• Rheumatoid artritis, hearing, conductive hearing loss, Sensorineural hearing loss, vasculitis, vestibular disorder

Romatoid Artrit’in işitme ve vestibüler sistem üzerine etkileri

Öz

Romatoid artrit (RA), CD4 (+) T hücreleri ve monositlerin, damardan inflamasyonlu sinoviyal dokuya ve sinoviyal sıvıya geçmesiyle karakterize, otoimmün bir hastalıktır. RA’nın işitmeye olan etkisi tartışılmaya devam etmektedir. İşitme kaybı sadece sensörinöral veya iletim tipinde olabilir. Ayrıca mikst tip işitme kaybı şeklinde de görülebilmektedir. İletim tipi işitme kaybı, timpano-ossiküler sistemin etkilenmesi ile ortaya çıkmaktadır. Sensörinöral kayıp ise nörit, vaskülit veya hastalığın tedavisi sırasında kullanılan ilaçların ototoksik etkilerine bağlı olarak ortaya çıkabilmektedir. RA, işitme bozukluğuna ek olarak vestibuler sistem bozukluğuna da sebep olabilmektedir. Vestibuler bozukluğun fizyolojisi tam açıklanamamıştır. Bu derlemede, RA’nın işitme ve vestibüler sistem üzerindeki etkileri, literatür bilgileri ışığında sunulmuştur.

Anahtar kelimeler: Romatoid artrit, işitme, iletim tipi işitme kaybı, sensörinöral tip işitme kaybı, vaskülit, vestibüler bozukluk

Anahtar Kelimeler

• Romatoid artrit, işitme, iletim tipi işitme kaybı, sensörinöral tip işitme kaybı, vaskülit, vestibüler bozukluk

Kaynakça

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