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The association between age and peroperative morbidity in carotid stenting cases

Yıl 2018, , 287 - 291, 28.12.2018
https://doi.org/10.18663/tjcl.482561

Öz

Aim: Carotid
artery stenosis is a geriatric population disease. It was considered that
advanced age is related to increased peroperative morbidity and mortality
during carotid stenting.

Material and Methods:The
study population includes 106 patients who were treated with carotid stenting
at Ankara Numune Education and Research Hospital between January 2017 and
August 2018 The aim of the study is to find the correlation between age and perioperative
morbidity and mortality rates.  

Results: The
group of patients below 55 years of age didn’t develop any morbidity except
marked hypotension in 2 patients. Patients aged over 75 did not develop any
hypotension and morbidity in this group is relatively high compared to patients
below 55 years of age. Age group between 55 and 65 developed 1 aphasia, 1
homonymous hemianopia and 1 mortality. There were 1 dyspasia, 2 hemiparesis and
1 mortality in patients between 65 and 75 years of age. Morbidity over 75 years
of age included 1 hemiparesis, 1 cranial nerve paresis and 1 mortality. No
correlation was found between age groups except patients below 55 years of age.
An increased morbidity and mortality rate was noted with advanced age though a
statistical correlation can not be applied. Hypotension was noted to decrease
with advanced age.







Conclusion: The
risk of carotid stenting below 55 years of age is minimal except hypotension
risk however perioperative morbidity and mortality is more pronounced with advanced
age without any hypotension.

Kaynakça

  • 1. Wendorff C, Wendorff H, Kuehnl A, Tsantilas P, Kallmayer M, Eckstein HH, Pelisek J. Impact of sex and age on carotid plaque instability in asymptomatic patients-results from the Munich Vascular Biobank. Vasa 2016; 45: 411-16.
  • 2. Ballotta E, Toniato A, Da Roit A, Lorenzetti R, Piatto G, Baracchini C. Carotid endarterectomy for asymptomatic carotid stenosis in the very elderly. J Vasc Surg 2015; 61: 382-88.
  • 3. Mo D, Wang B, Ma N, Gao F, Miao Z. Comparative outcomes of carotid artery stenting for asymptomatic and symptomatic carotid artery stenosis: a single-center prospective study. J Neurointerv Surg 2016; 8: 126-29.
  • 4. Rosenfield K, Matsumura JS, Chaturvedi S et al. Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis. N Engl J Med 2016; 374: 1011-20.
  • 5. Lam RC, Lin SC, DeRubertis B, Hynecek R, Kent KC, Faries PL. The impact of increasing age on anatomic factors affecting carotid angioplasty and stenting. J Vasc Surg 2007; 45: 875-80.
  • 6. Lin SC, Trocciola SM, Rhee J et al. Analysis of anatomic factors and age in patients undergoing carotid angioplasty and stenting. Ann Vasc Surg 2005; 19: 798-804.
  • 7. Sullivan KM, Dean A, Soe MM. OpenEpi: a web-based epidemiologic and statistical calculator for public health. Public health reports 2009; 124: 471-74.
  • 8. Nam HJ, Heo SH, Kim BJ, San Lee J, Youn HC, Lee JS, Kwon SU, Bushnell CD, Chang DI. Long-Term Outcome After Carotid Endarterectomy in Patients with Ischemic Heart Disease. World Neurosurg 2018; 110: 806-14.
  • 9. Antoniou GA, Georgiadis GS, Georgakarakos EI, Antoniou SA, Bessias N, Smyth JV, Murray D, Lazarides MK. Meta-analysis and meta-regression analysis of outcomes of carotid endarterectomy and stenting in the elderly. JAMA Surg 2013; 148: 1140-52.
  • 10. Nanto M, Goto Y, Yamamoto H, Tanigawa S, Takado M, Ogawa T, Nakahara Y. Periprocedural Outcomes of Carotid Artery Stenting in Elderly Patients. J Stroke Cerebrovasc Dis 2018; 27: 103-7.
  • 11. Roubin GS, Iyer S, Halkin A, Vitek J, Brennan C. Realizing the potential of carotid artery stenting: Proposed paradigms for patient selection and procedural technique. Circulation 2006; 113: 2021-30.
  • 12. Antoniou GA, Georgiadis GS, Georgakarakos E, Antoniou SA, Bessias N, Smyth JV, Murray D, Lazarides MK. Meta-analysis and meta-regression analysis of outcomes of carotid endarterectomy and stenting in the elderly. JAMA Surg 2013; 148: 1140-52.
  • 13. Qureshi AI, Chaudhry SA, Qureshi MH, Suri MF. Rates and predictors of 5-year survival in a national cohort of asymptomatic elderly patients undergoing carotid revascularization. Neurosurgery 2015; 76: 34-41.
  • 14. Ledwoch J, Staubach S, Segerer M, Strohm H, Mudra H. Carotid artery stenting in clinical practice depending on patient age. Catheter Cardiovasc Interv 2017; 90: 451-60.
  • 15. Lin CM, Chang YJ, Liu CK, Yu CS, Lu HH. First-ever ischemic stroke in elderly patients: predictors of functional outcome following carotid artery stenting. Clin Interv Aging 2016; 11: 985-95.
  • 16. Rubio G, Karwowski JK, DeAmorim H, Goldstein LJ, Bornak A. Predicting Factors Associated with Postoperative Hypotension following Carotid Artery Stenting. Ann Vasc Surg 2018 pii: S0890-5096(18)30571-5.
  • 17. Gökçal E, Niftaliyev E, Deniz Ç, Ergelen M, Güzel V, Göktekin Ö, Asil T. Prolonged hypotension after carotid artery stenting: incidence, predictors and consequences. Acta Neurochir 2017; 159: 2081-87.
  • 18. Cirbian J, Echaniz G, Gené A, Silva L, Fernández-Valenzuela V, de Nadal M. Incidence and timing of hypotension after transcervical carotid artery stenting: correlation with postoperative complications. Catheter Cardiovasc Interv 2014; 84: 1013-18.
  • 19. Nanto M1, Goto Y, Yamamoto H, Tanigawa S, Takeuchi H, Nakahara Y, Tenjin H, Takado M. Complications and Predictors of Hypotension Requiring Vasopressor after Carotid Artery Stenting. Neurol Med Chir 2017; 57: 115-21.

Karotis stentlemede yaş ve peroperatif morbidite İlişkisi

Yıl 2018, , 287 - 291, 28.12.2018
https://doi.org/10.18663/tjcl.482561

Öz

Amaç: Karotid
arter stenozu ileri yaş olgularda görülen bir hastalıktır. Karotid stenozu
tedavisinde uygulanan karotis stentlemede peroperatif morbidite ve mortalitenin
yaşa bağlı arttığı belirtilmektedir.

Gereç ve Yöntem: Bu
çalışmada Ankara Numune Eğitim ve Araştırma Hastanesinde 2017 Ocak ve 2018
Ağustos tarihleri arasında karotis stentleme yapılan 106 olgu analiz edilmiş
olup yaş ve risk faktörleri ile peroperatif morbidite ve mortalite ilişkisi
araştırılmıştır.

Bulgular: 106
olgunun analiz edildiği bu çalışmada 55 yaş altı görülen olgularda 2 olguda
görülen hipotansiyon dışında herhangi bir morbidite gözlenmemiştir. 75 yaş ve
üzeri olgularda ise hipotansiyon görülmemiş olup 55 yaş altı gruba göre daha
fazla morbidite mevcuttur. 55-65 yaş arası yer alan grupta ise 1 olguda afazi,
1 olguda sol homonim hemianopsi, 1 mortalite olmuştur. 65-75 yaş arası grupta
ise 2 olguda kısmi parezi, 1 olguda disfazi gözlenmiş ve 1 olguda postoperatif
eksitus olmuştur. 75 yaş üzeri grupta ise 1 olguda silik hemiparezi, 1 olguda
kranial sinir parezisi ve gözlerde deviasyon görülmüş olup postoperatif dönemde
nöbet görülen 1 olgu ise eksitus olmuştur. Yaş artışı ile birlikte peroperatif morbidite
ve mortalite oranlarında artış olduğu oransal olarak görülse de anlamlı bir
istatistiksel sonuç elde edilememektedir. Hipotansiyonun ise yaşla birlikte
azaldığı görülmektedir.







Sonuç: 55 yaş altı karotis stentlemede risk minimal
olup hipotansiyon oransal olarak fazla görülmekte, 75 yaş üzeri grupta da
hipotansiyon görülmeyip komplikasyonlar artış göstermektedir. 

Kaynakça

  • 1. Wendorff C, Wendorff H, Kuehnl A, Tsantilas P, Kallmayer M, Eckstein HH, Pelisek J. Impact of sex and age on carotid plaque instability in asymptomatic patients-results from the Munich Vascular Biobank. Vasa 2016; 45: 411-16.
  • 2. Ballotta E, Toniato A, Da Roit A, Lorenzetti R, Piatto G, Baracchini C. Carotid endarterectomy for asymptomatic carotid stenosis in the very elderly. J Vasc Surg 2015; 61: 382-88.
  • 3. Mo D, Wang B, Ma N, Gao F, Miao Z. Comparative outcomes of carotid artery stenting for asymptomatic and symptomatic carotid artery stenosis: a single-center prospective study. J Neurointerv Surg 2016; 8: 126-29.
  • 4. Rosenfield K, Matsumura JS, Chaturvedi S et al. Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis. N Engl J Med 2016; 374: 1011-20.
  • 5. Lam RC, Lin SC, DeRubertis B, Hynecek R, Kent KC, Faries PL. The impact of increasing age on anatomic factors affecting carotid angioplasty and stenting. J Vasc Surg 2007; 45: 875-80.
  • 6. Lin SC, Trocciola SM, Rhee J et al. Analysis of anatomic factors and age in patients undergoing carotid angioplasty and stenting. Ann Vasc Surg 2005; 19: 798-804.
  • 7. Sullivan KM, Dean A, Soe MM. OpenEpi: a web-based epidemiologic and statistical calculator for public health. Public health reports 2009; 124: 471-74.
  • 8. Nam HJ, Heo SH, Kim BJ, San Lee J, Youn HC, Lee JS, Kwon SU, Bushnell CD, Chang DI. Long-Term Outcome After Carotid Endarterectomy in Patients with Ischemic Heart Disease. World Neurosurg 2018; 110: 806-14.
  • 9. Antoniou GA, Georgiadis GS, Georgakarakos EI, Antoniou SA, Bessias N, Smyth JV, Murray D, Lazarides MK. Meta-analysis and meta-regression analysis of outcomes of carotid endarterectomy and stenting in the elderly. JAMA Surg 2013; 148: 1140-52.
  • 10. Nanto M, Goto Y, Yamamoto H, Tanigawa S, Takado M, Ogawa T, Nakahara Y. Periprocedural Outcomes of Carotid Artery Stenting in Elderly Patients. J Stroke Cerebrovasc Dis 2018; 27: 103-7.
  • 11. Roubin GS, Iyer S, Halkin A, Vitek J, Brennan C. Realizing the potential of carotid artery stenting: Proposed paradigms for patient selection and procedural technique. Circulation 2006; 113: 2021-30.
  • 12. Antoniou GA, Georgiadis GS, Georgakarakos E, Antoniou SA, Bessias N, Smyth JV, Murray D, Lazarides MK. Meta-analysis and meta-regression analysis of outcomes of carotid endarterectomy and stenting in the elderly. JAMA Surg 2013; 148: 1140-52.
  • 13. Qureshi AI, Chaudhry SA, Qureshi MH, Suri MF. Rates and predictors of 5-year survival in a national cohort of asymptomatic elderly patients undergoing carotid revascularization. Neurosurgery 2015; 76: 34-41.
  • 14. Ledwoch J, Staubach S, Segerer M, Strohm H, Mudra H. Carotid artery stenting in clinical practice depending on patient age. Catheter Cardiovasc Interv 2017; 90: 451-60.
  • 15. Lin CM, Chang YJ, Liu CK, Yu CS, Lu HH. First-ever ischemic stroke in elderly patients: predictors of functional outcome following carotid artery stenting. Clin Interv Aging 2016; 11: 985-95.
  • 16. Rubio G, Karwowski JK, DeAmorim H, Goldstein LJ, Bornak A. Predicting Factors Associated with Postoperative Hypotension following Carotid Artery Stenting. Ann Vasc Surg 2018 pii: S0890-5096(18)30571-5.
  • 17. Gökçal E, Niftaliyev E, Deniz Ç, Ergelen M, Güzel V, Göktekin Ö, Asil T. Prolonged hypotension after carotid artery stenting: incidence, predictors and consequences. Acta Neurochir 2017; 159: 2081-87.
  • 18. Cirbian J, Echaniz G, Gené A, Silva L, Fernández-Valenzuela V, de Nadal M. Incidence and timing of hypotension after transcervical carotid artery stenting: correlation with postoperative complications. Catheter Cardiovasc Interv 2014; 84: 1013-18.
  • 19. Nanto M1, Goto Y, Yamamoto H, Tanigawa S, Takeuchi H, Nakahara Y, Tenjin H, Takado M. Complications and Predictors of Hypotension Requiring Vasopressor after Carotid Artery Stenting. Neurol Med Chir 2017; 57: 115-21.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Özgün Makale
Yazarlar

Gürdal Orhan

Ergün Dağlıoğlu Bu kişi benim

Yayımlanma Tarihi 28 Aralık 2018
Yayımlandığı Sayı Yıl 2018

Kaynak Göster

APA Orhan, G., & Dağlıoğlu, E. (2018). Karotis stentlemede yaş ve peroperatif morbidite İlişkisi. Turkish Journal of Clinics and Laboratory, 9(4), 287-291. https://doi.org/10.18663/tjcl.482561
AMA Orhan G, Dağlıoğlu E. Karotis stentlemede yaş ve peroperatif morbidite İlişkisi. TJCL. Aralık 2018;9(4):287-291. doi:10.18663/tjcl.482561
Chicago Orhan, Gürdal, ve Ergün Dağlıoğlu. “Karotis Stentlemede Yaş Ve Peroperatif Morbidite İlişkisi”. Turkish Journal of Clinics and Laboratory 9, sy. 4 (Aralık 2018): 287-91. https://doi.org/10.18663/tjcl.482561.
EndNote Orhan G, Dağlıoğlu E (01 Aralık 2018) Karotis stentlemede yaş ve peroperatif morbidite İlişkisi. Turkish Journal of Clinics and Laboratory 9 4 287–291.
IEEE G. Orhan ve E. Dağlıoğlu, “Karotis stentlemede yaş ve peroperatif morbidite İlişkisi”, TJCL, c. 9, sy. 4, ss. 287–291, 2018, doi: 10.18663/tjcl.482561.
ISNAD Orhan, Gürdal - Dağlıoğlu, Ergün. “Karotis Stentlemede Yaş Ve Peroperatif Morbidite İlişkisi”. Turkish Journal of Clinics and Laboratory 9/4 (Aralık 2018), 287-291. https://doi.org/10.18663/tjcl.482561.
JAMA Orhan G, Dağlıoğlu E. Karotis stentlemede yaş ve peroperatif morbidite İlişkisi. TJCL. 2018;9:287–291.
MLA Orhan, Gürdal ve Ergün Dağlıoğlu. “Karotis Stentlemede Yaş Ve Peroperatif Morbidite İlişkisi”. Turkish Journal of Clinics and Laboratory, c. 9, sy. 4, 2018, ss. 287-91, doi:10.18663/tjcl.482561.
Vancouver Orhan G, Dağlıoğlu E. Karotis stentlemede yaş ve peroperatif morbidite İlişkisi. TJCL. 2018;9(4):287-91.


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