DİYABETES MELLİTUS TANILI HASTALARDA İLAÇ UYUMUNUN DİYABETİK AYAK VE KLİNİK DEĞİŞKENLERLE İLİŞKİSİ

Yıl 2025, Cilt: 19 Sayı: 4, 395 - 404, 08.12.2025

Dilara Öztoprak , Meltem Yılmaz , Hasan Sivrikaya , Onur Öztürk

https://doi.org/10.21763/tjfmpc.1720378

Öz

Giriş: Dünya genelinde diyabet prevalansı artmakta ve komplikasyonlar bireylerin yaşam kalitesini düşürmektedir. Çalışmamızda diyabet hastalarının tedavi uyumu ile diyabetik ayak varlığı arasındaki ilişki incelenmiştir.
Yöntem: Gözlemsel kontrol gruplu çalışmamız 01.08.2024-31.12.2024 tarihleri arasında Samsun Eğitim ve Araştırma Hastanesinde 18 yaş ve üzeri diyabet tanılı hastalarla yapılmıştır. Katılımcılara sosyodemografik ve klinik veriler, diyabetik ayak veri formu ve Morisky-8 Maddeli İlaca Uyum Anketi (MTUÖ-8) uygulanmıştır. Analizler SPSS ile gerçekleştirilmiştir.
Bulgular: Çalışmaya 343 hasta dahil edilmiştir. Morisky-8 ile tedavi uyumu %42,9 kötü, %33,5 orta, %23,6 iyi olarak bulunmuştur. Diyabetik ayak gelişimi açısından genel tedavi uyumu grupları arasında anlamlı fark yoktur; ancak ilaç yazdırmayı unutanlarda ayak yarası daha sık görülmüştür (p=0,013). Ayak yarası ile cinsiyet (p<0,001), medeni durum (p=0,034), eğitim (p=0,040), gelir (p<0,001), ilaç türü (p<0,001), kontrol sıklığı (p=0,002), kontrol yeri (p<0,001), kan şekeri ölçümü (p<0,001) ve diyet (p<0,001) arasında anlamlı ilişki bulunmuştur. Ayak yarası süresi arttıkça MTUÖ-8 puanları düşmekte olup, aralarında anlamlı bir ilişki bulunmuştur (p=0,026).
Sonuç: Diyabetik ayak gelişimi ile genel tedavi uyumu ilişkili bulunmasa da, ilaç kullanımı alışkanlıkları, sosyodemografik faktörler ve takip düzeni diyabetik ayak oluşumunda etkili olabilir.

Anahtar Kelimeler

Diyabetes Mellitus , Diyabetik Ayak , İnsülin , Tedavi Uyumu

Etik Beyan

Araştırma için Samsun Üniversitesi Girişimsel Olmayan Klinik Araştırmalar Etik Kurulu’ndan 05.06.2024 tarihli ve 2024/11/10 karar nolu onay almıştır.

Destekleyen Kurum

Bu araştırma herhangi bir fonlama kuruluşu/sektöründen hibe almamıştır.

Teşekkür

Yazarlar, çalışmaya katılan tüm bireylere gösterdikleri özenli iş birliği ve ayırdıkları zaman için içten teşekkürlerini sunar.

THE IMPACT OF MEDICATION ADHERENCE ON DIABETIC FOOT OUTCOMES AND CLINICAL VARIABLES IN PATIENTS WITH DIABETES MELLITUS

Öz

Introduction: The prevalence of diabetes is increasing worldwide, leading to complications that reduce patients' quality of life. This study examined the relationship between treatment adherence and the presence of diabetic foot in diabetic patients.
Methods: This observational study with a control group was conducted between August 1 and December 31, 2024, at Samsun Training and Research Hospital with diabetic patients aged 18 and over. Participants completed sociodemographic and clinical data forms, a diabetic foot data form, and the Morisky 8-Item Medication Adherence Scale (MMAS-8). Data were analyzed using SPSS.
Results: A total of 343 patients were included. According to MMAS-8, treatment adherence was poor in 42.9%, moderate in 33.5%, and good in 23.6% of patients. No significant difference was found between adherence groups regarding diabetic foot development; however, patients who forgot to refill their medication had a significantly higher incidence of foot ulcers (p=0.013). Significant associations were found between foot ulcers and gender (p<0.001), marital status (p=0.034), education level (p=0.040), income (p<0.001), type of medication (p<0.001), frequency of medical check-ups (p=0.002), location of follow-up (p<0.001), regular blood glucose monitoring (p<0.001), and diet (p<0.001). As the duration of foot wounds increases, MTUÖ-8 scores decrease, and a significant relationship has been found between them (p=0.026).
Conclusion: Although no significant association was found between diabetic foot development and overall treatment adherence, medication habits, sociodemographic factors, and follow-up routines may play a crucial role in the formation of diabetic foot.

Anahtar Kelimeler

Diabetes Mellitus , Diabetic Foot , Insulin , Medication Adherence

Kaynakça

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