The zebrafish model in dental research: an alternative experimental approach for Türkiye

Öz

Zebrafish (Danio rerio) is widely used in medical and biomedical research because of its rapid development, transparent embryos, genetic similarity to humans, and cost-effective maintenance. In recent years, it has also gained attention in dental research, particularly in craniofacial development, oral pathogen models, and toxicity assessment of dental biomaterials. Although its use in dental research in Türkiye remains limited, the zebrafish model may provide an ethical, economical, and translationally valuable alternative to conventional animal models.

Anahtar Kelimeler

• Zebrafish
• Danio rerio
• biomedical research
• dentistry
• animal model

Diş hekimliği araştırmalarında zebra balığı modeli: Türkiye için alternatif bir deneysel yaklaşım

Öz

Zebra balığı (Danio rerio), hızlı gelişimi, embriyolarının saydamlığı, genetik benzerliği ve düşük maliyetli bakım koşulları nedeniyle tıp ve biyomedikal araştırmalarda yaygın kullanılan bir model organizmadır. Son yıllarda diş hekimliği alanında da kraniofasiyal gelişim, oral patojenler ve dental biyomateryallerin toksisite değerlendirmeleri dikkat çekmektedir. Türkiye’de dental araştırmalarda kullanımı henüz sınırlı olan zebra balığı modeli, geleneksel hayvan modellerine etik, ekonomik ve translasyonel açıdan güçlü bir alternatif sunabilir.

Anahtar Kelimeler

• Zebra balığı
• Danio rerio
• biyomedikal araştırmalar
• diş hekimliği
• hayvan modeli

Kaynakça

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