SERVİKSİN CAMSI HÜCRELİ KARSİNOMU: NADİR GÖRÜLEN BİR OLGU SUNUMU

Öz

Giriş: Camsı hücreli karsinom, uterin serviksi tutan, agresif gidişli ve görece olarak kötü prognoza sahip, tüm servikal kanserlerin %1’den azını oluşturan çok nadir bir klinik antitedir. Adenoskuamöz karsinomun bir alt tipi olarak tanımlanmıştır. Özel bir histolojik görüntüye sahiptir. Olgu: Biz burada; serviksin glassy hücreli karsinomunu sunduk ve bu tümörün klinik, morfolojik, histokimyasal, immünhistokimyasal özelliklerini literatür eşliğinde tartıştık. Sonuç: Bu tümörler daha kötü prognoza sahip olduklarından doğru tanı koymak ve diğer tip cervikal karsinomlardan ayırmak oldukça önemlidir.

Anahtar Kelimeler

• Serviks uteri, Serviksin camsı hücreli karsinomu.

GLASSY CELL CARCINOMA OF THE UTERINE CERVIX: A RARE CASE REPORT

Öz

Introduction: Glassy cell carcinoma is a very rare clinical entitiy involving uterine cervix, comprising <1% of all cervical cancers with aggressive course and relatively poor prognosis. It was defined as a subgroup of cervical adenosquamous carcinoma. Its histologic appearance is distinctive. Case: We presented a case of glassy cell carcinoma of the cervix and discussed the clinical, morphological, histochemical and immunohistochemical characteristics of this tumor with the review of the literature. Conclusion: Because this group tumors prognosis has been poor, it was very important to be made to correctly identify and distinguish these tumors from other types of cervical carsinomas

Anahtar Kelimeler

• Cervix uteri, Glassy cell carcinoma of the cervix

Kaynakça

1. 1. Littman P, Clement P B, Henriksen B, et al. Glassy cell carcinoma of the cervix.Cancer 1976;37 (5):2238-2246
2. 2. Pak HY, Yokota S B, Paladugu R R, Agliozzo C M. Glassy cell carcinoma of the cervix, cytologic and clinicopathologic analysis . Cancer 1983; 52 (2) : 307-312
3. 3. Hadi R, Kumar M, Pat S, et al. Glassy cell carcinoma (GCC) of uterine cervix. Sri Lanka Journal of Obstetrics and Gynaecology 2011; 33(1): 65-67
4. 4. Deshpande AH, Kotwal MN , Bobhate SK. Glassy cell carcinoma of the uterine cervix a rare histology: report of three cases with a review of the literature. Indian J Cancer 2004; 41(2): 92-95.
5. 5. Costa MJ, Kenny MB, Hewan-Lowe K, Judd R. Glassy cell features in adenosquamous carcinoma of the uterine cervix. Histologic, ultrastructural, immunohistochemical, and clinical fi ndings. Am J Clin Pathol 1991;96(4):520- 528.
6. 6. Ukita Y, subamoto HT, Kato T, Suno S, Shibahara H. A case of primary metastatic glassy cell carcinoma of the uterine cervix that responded to combined docetaxel and carboplatin. Gynecologic Oncology Reports 2013;6: 19–21
7. 7. Nagai T, Okubo T , Sakaguchi R, Seki H, Takeda S. Glassy cell carcinoma of the uterine cervix responsive to neoadjuvant intraarterial chemotherapy. Int J Clin Oncol 2008; 13(6): 541–544
8. 8. Gray HJ, Garcia R, Tamimi HK, et al. Glassy cell carcinoma of the cervix revisited. Gynecol Oncol 2002;85(2):274- 277.