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An exceptional survival term in primary neuroendocrine carcinoma of the vagina

Cilt: 21 Sayı: 1 6 Aralık 2019
  • Malek Bouhani *
  • Zemni İnes
  • Yasmine Ayari
  • Mohamed Amine Bouida
  • Riadh Chargui
  • Khaled Rahal
Türk Jinekolojik Onkoloji Dergisi Kapak
Türk Jinekolojik Onkoloji Dergisi
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An exceptional survival term in primary neuroendocrine carcinoma of the vagina

Öz

Introduction: Primary vaginal malignant tumors are rare, especially neuroendocrine tumors. The primary small cell carcinoma of the vagina is an aggressive tumor with poor prognosis because of early recurrence and metastasis.

Aim:  to report the complexity of treatment of primary neuroendocrine carcinoma of vagina, and its metastasis.

Material &methods: we report a retrospective case of primary neuroendocrine carcinoma of vagina treated in our institution.

Results:  We report a case of a 37-year-old woman who was diagnosed with a small cell carcinoma of the vagina without distant metastasis. The primary vaginal tumor was treated by surgery, brachytherapy, and chemotherapy. The first recurrence appeared seven years after initial diagnosis, which was a pulmonary metastasis, treated surgically. Seven years after this recurrence, she was treated with chemotherapy and surgery for another pulmonary metastasis. Fifteen years after the initial diagnosis, the patient underwent surgery for brain metastasis. She died eighteen months after the third recurrence.

Conclusions: This case splendidly illustrates a long survival term of a tumor known with poor prognosis.

Anahtar Kelimeler

Kaynakça

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  2. Reference 2. Prasad CJ, Ray JA, and Kessler S. Primary small cell carcinoma of the vagina arising in a background of atypical adenosis. Cancer 1992;70(10):2484–7.
  3. Reference 3. Miliauskas JR, Leong AS. Small cell (neuroendocrine) carcinoma of the vagina. Histopathology 1992;21:371–4.
  4. Reference 4. Howitt BE, Kelly P, Mc Cluggage WG. Pathology of Neuroendocrine Tumours of the Female Genital Tract. Curr Oncol Rep 2017;19(9):59.
  5. Reference 5. Bhalodia JN, Kapapura DV, and Parekh MN, Primary small cell neuroendocrine carcinoma of vagina: a rare case report. Patholog Res Int 2011;2011:306921.
  6. Reference 6. Kostamo K, Peart M, McKenzie N, Holloman C, Carlan SJ, Ge L, et al. Novel Treatment of Small-Cell Neuroendocrine of the Vagina. Case Rep Oncol Med 2018;2018:9157036.
  7. Reference 7. Cohen JG, Chan JK, Kapp DS. The management of small-cell carcinomas of the gynecologic tract. Curr Opin Oncol 2012;24(5):572-9.
  8. Reference 8. Joseph RE, Enghardt MH, Doering DL, Brown BF, Shaffer DW, Raval HB. Small cell neuroendocrine carcinoma of the vagina. Cancer 1992;70:784–9.

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

Olgu Sunumu

Yazarlar

Zemni İnes Bu kişi benim
Tunisia

Yasmine Ayari Bu kişi benim
Tunisia

Mohamed Amine Bouida Bu kişi benim
Tunisia

Riadh Chargui Bu kişi benim
Tunisia

Khaled Rahal Bu kişi benim

Yayımlanma Tarihi

6 Aralık 2019

Gönderilme Tarihi

7 Nisan 2019

Kabul Tarihi

1 Ağustos 2019

Yayımlandığı Sayı

Yıl 2018 Cilt: 21 Sayı: 1

IZ

https://izlik.org/JA86TZ36PE

Kaynak Göster

RIS / Bibtex
APA
Bouhani, M., İnes, Z., Ayari, Y., Bouida, M. A., Chargui, R., & Rahal, K. (2019). An exceptional survival term in primary neuroendocrine carcinoma of the vagina. Türk Jinekolojik Onkoloji Dergisi, 21(1), 24-25. https://izlik.org/JA86TZ36PE
AMA
1.Bouhani M, İnes Z, Ayari Y, Bouida MA, Chargui R, Rahal K. An exceptional survival term in primary neuroendocrine carcinoma of the vagina. TRSGO Dergisi. 2019;21(1):24-25. https://izlik.org/JA86TZ36PE
Chicago
Bouhani, Malek, Zemni İnes, Yasmine Ayari, Mohamed Amine Bouida, Riadh Chargui, ve Khaled Rahal. 2019. “An exceptional survival term in primary neuroendocrine carcinoma of the vagina”. Türk Jinekolojik Onkoloji Dergisi 21 (1): 24-25. https://izlik.org/JA86TZ36PE.
EndNote
Bouhani M, İnes Z, Ayari Y, Bouida MA, Chargui R, Rahal K (01 Aralık 2019) An exceptional survival term in primary neuroendocrine carcinoma of the vagina. Türk Jinekolojik Onkoloji Dergisi 21 1 24–25.
IEEE
[1]M. Bouhani, Z. İnes, Y. Ayari, M. A. Bouida, R. Chargui, ve K. Rahal, “An exceptional survival term in primary neuroendocrine carcinoma of the vagina”, TRSGO Dergisi, c. 21, sy 1, ss. 24–25, Ara. 2019, [çevrimiçi]. Erişim adresi: https://izlik.org/JA86TZ36PE
ISNAD
Bouhani, Malek - İnes, Zemni - Ayari, Yasmine - Bouida, Mohamed Amine - Chargui, Riadh - Rahal, Khaled. “An exceptional survival term in primary neuroendocrine carcinoma of the vagina”. Türk Jinekolojik Onkoloji Dergisi 21/1 (01 Aralık 2019): 24-25. https://izlik.org/JA86TZ36PE.
JAMA
1.Bouhani M, İnes Z, Ayari Y, Bouida MA, Chargui R, Rahal K. An exceptional survival term in primary neuroendocrine carcinoma of the vagina. TRSGO Dergisi. 2019;21:24–25.
MLA
Bouhani, Malek, vd. “An exceptional survival term in primary neuroendocrine carcinoma of the vagina”. Türk Jinekolojik Onkoloji Dergisi, c. 21, sy 1, Aralık 2019, ss. 24-25, https://izlik.org/JA86TZ36PE.
Vancouver
1.Malek Bouhani, Zemni İnes, Yasmine Ayari, Mohamed Amine Bouida, Riadh Chargui, Khaled Rahal. An exceptional survival term in primary neuroendocrine carcinoma of the vagina. TRSGO Dergisi [Internet]. 01 Aralık 2019;21(1):24-5. Erişim adresi: https://izlik.org/JA86TZ36PE