SERVİKSİN CAMSI HÜCRELİ KARSİNOMU: NADİR GÖRÜLEN BİR OLGU SUNUMU

Yıl 2014, Cilt: 17 Sayı: 3, 0 - 0, 01.07.2014

Nermin Koç Hülya Yavuz Ecmel Kaygusuz Handan Çetiner

Öz

Giriş: Camsı hücreli karsinom, uterin serviksi tutan, agresif gidişli ve görece olarak kötü prognoza sahip, tüm servikal kanserlerin
%1’den azını oluşturan çok nadir bir klinik antitedir. Adenoskuamöz karsinomun bir alt tipi olarak tanımlanmıştır. Özel bir histolojik
görüntüye sahiptir.
Olgu: Biz burada; serviksin glassy hücreli karsinomunu sunduk ve bu tümörün klinik, morfolojik, histokimyasal, immünhistokimyasal
özelliklerini literatür eşliğinde tartıştık.
Sonuç: Bu tümörler daha kötü prognoza sahip olduklarından doğru tanı koymak ve diğer tip cervikal karsinomlardan ayırmak
oldukça önemlidir.

Anahtar Kelimeler

Serviks uteri, Serviksin camsı hücreli karsinomu.

GLASSY CELL CARCINOMA OF THE UTERINE CERVIX: A RARE CASE REPORT

Öz

Introduction: Glassy cell carcinoma is a very rare clinical entitiy involving uterine cervix, comprising <1% of all cervical cancers
with aggressive course and relatively poor prognosis. It was defined as a subgroup of cervical adenosquamous carcinoma. Its
histologic appearance is distinctive.
Case: We presented a case of glassy cell carcinoma of the cervix and discussed the clinical, morphological, histochemical and immunohistochemical
characteristics of this tumor with the review of the literature.
Conclusion: Because this group tumors prognosis has been poor, it was very important to be made to correctly identify and distinguish
these tumors from other types of cervical carsinomas

Anahtar Kelimeler

Cervix uteri, Glassy cell carcinoma of the cervix

Kaynakça

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• 2. Pak HY, Yokota S B, Paladugu R R, Agliozzo C M. Glassy cell carcinoma of the cervix, cytologic and clinicopathologic analysis . Cancer 1983; 52 (2) : 307-312
• 3. Hadi R, Kumar M, Pat S, et al. Glassy cell carcinoma (GCC) of uterine cervix. Sri Lanka Journal of Obstetrics and Gynaecology 2011; 33(1): 65-67
• 4. Deshpande AH, Kotwal MN , Bobhate SK. Glassy cell carcinoma of the uterine cervix a rare histology: report of three cases with a review of the literature. Indian J Cancer 2004; 41(2): 92-95.
• 5. Costa MJ, Kenny MB, Hewan-Lowe K, Judd R. Glassy cell features in adenosquamous carcinoma of the uterine cervix. Histologic, ultrastructural, immunohistochemical, and clinical fi ndings. Am J Clin Pathol 1991;96(4):520- 528.
• 6. Ukita Y, subamoto HT, Kato T, Suno S, Shibahara H. A case of primary metastatic glassy cell carcinoma of the uterine cervix that responded to combined docetaxel and carboplatin. Gynecologic Oncology Reports 2013;6: 19–21
• 7. Nagai T, Okubo T , Sakaguchi R, Seki H, Takeda S. Glassy cell carcinoma of the uterine cervix responsive to neoadjuvant intraarterial chemotherapy. Int J Clin Oncol 2008; 13(6): 541–544
• 8. Gray HJ, Garcia R, Tamimi HK, et al. Glassy cell carcinoma of the cervix revisited. Gynecol Oncol 2002;85(2):274- 277.