Tip-2 Diyabetli Bireylerde Faz Açısının Fiziksel Aktivite ve Antropometrik Ölçümler ile İlişkisi

Öz

Amaç: Biyoelektrik impedans analizi ile elde edilen faz açısı, hücresel sağlık, beslenme durumu, fonksiyon kaybı ve mortalite ile ilişkilidir. Bu çalışmada, tip 2 diyabetli bireylerde faz açısının fiziksel aktivite ve antropometrik ölçümlerle ilişkisi ve fonksiyonel durumun belirlenmesinde potansiyel biyomarker olarak kullanımı değerlendirilmiştir. Gereç ve Yöntemler: Çalışmaya 18–65 yaş arası, tip 2 diyabet tanılı, en az 4 saattir aç, son 24 saatte alkol almamış ve 24–48 saatte ağır fiziksel aktivite yapmamış 125 gönüllü katılmıştır. Vücut kompozisyonu ve faz açısı InBody S10 (Biospace, Seul, Kore), boy SECA- 213 stadiyometre (SECA, Hamburg, Almanya), ağırlık Honor Scale-2 tartı; bel ve üst kol çevresi esmeyen mezura aracılığıyla standart antropometrik protokollerle ölçülmüştür. Katılımcıların fiziksel aktiviteye ilişkin düzeyleri, Uluslararası Fiziksel Aktivite Anketi kısa formu kullanılarak değerlendirilmiştir. Erkek ve kadın katılımcılar arasındaki karşılaştırmalar, verilerin dağılım özelliklerine bağlı olarak Bağımsız Örneklem t-testi veya Mann–Whitney U testi kullanılarak gerçekleştirilmiştir. Sürekli değişkenler arasındaki ilişkiler ise, veri dağılımına göre Pearson veya Spearman korelasyon katsayıları ile değerlendirilmiştir. Bulgular: Tüm vücut faz açısı ortalaması 5.54 ± 0.78°, fiziksel aktivite ortalama MET skoru ise 1121.15 ± 981.04 olarak saptanmıştır. Fiziksel Aktivite MET-skoru ile tüm vücut faz açısı arasında istatistiksel olarak önemli, pozitif yönde, yüksek düzeyde bir ilişki bulunmuştur (r: 0.677, p<0.05). Hastaların vücut ağırlığı, vücut yağ yüzdesi, vücut yağ kütlesi, kemik mineral içeriği, yağsız vücut kütlesi, toplam vücut suyu, segmental faz açıları ile tüm vücut faz açısı arasında istatistiksel açıdan önemli bir korelasyon bulunmuştur (p<0.05). Sonuç: Faz açısı, tip 2 diyabetli bireylerde fiziksel aktivite, antropometrik ölçümler ve genel durum hakkında bilgi sağlayan non-invaziv bir parametre olarak kullanılabilir. Ancak hastalık, yaş, cinsiyet ve beden kütle indeksine özgü referans standartlar ile sınır değerlerin belirlenmesi için daha fazla çalışmaya ihtiyaç vardır.

Anahtar Kelimeler

• Tip-2 diyabet
• Faz açıs
• Biyoelektrik impedans analizi
• Antropometrik ölçümler

Association of Phase Angle with Physical Activity and Anthropometric Measurements in Individuals with Type 2 Diabetes

Öz

Aim: Phase angle from bioelectrical impedance analysis is associated with cellular health, nutritional status, functional decline, and mortality. This study evaluated its relationship with physical activity and anthropometric measures in type 2 diabetes and its potential as a biomarker of functional status. Material and Methods: The study recruited 125 volunteers aged 18–65 years with type 2 diabetes, fasting ≥4 h, without alcohol in the past 24 h or vigorous activity in 24–48 h. Body composition and phase angle were measured by InBody S10 (Biospace, Seoul, Korea); height by SECA-213 stadiometer (SECA, Hamburg, Germany); weight by Honor Scale-2; waist and mid-arm circumferences by nonelastic tape using standard anthropometric protocols. Physical activity levels were determined using data obtained from the short-form International Physical Activity Questionnaire (IPAQ-SF). Sex-based differences were analyzed using either the Independent Samples t-test or the Mann–Whitney U test, according to the distributional characteristics of the data. Associations between continuous variables were examined using Pearson’s or Spearman’s correlation analyses based on data distribution. Results: Mean whole-body phase angle was 5.54 ± 0.78° and mean physical activity MET score 1121.15 ± 981.04. A significant positive high correlation was found between MET score and phase angle (r =0.677, p<0.05). Whole-body phase angle also correlated significantly with body weight, body fat percentage, fat mass, bone mineral content, fat-free mass, total body water, and segmental phase angles (p<0.05). Conclusion: Phase angle may serve as a non-invasive indicator of physical activity, anthropometry, and overall status in type 2 diabetes. However, further studies are needed to establish disease-, age-, sex-, and BMI-specific reference standards and cut-off values

Anahtar Kelimeler

• Type-2 diabetes
• Phase angle
• Bioelectrical impedance analysis
• Anthropometric measurements

Kaynakça

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