Araştırma Makalesi

Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum

Cilt: 11 Sayı: 2 28 Ağustos 2024
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Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum

Öz

This study was conducted to determine the antioxidant activity, lipid peroxidation inhibitory effect and antimicrobial properties of Heracleum persicum plant. DPPH (2, 2-diphenyl, 1-picrylhydrazyl) method was used to determine antioxidant activity, and the Folin method was used to determine total phenolic content. Disc diffusion method was applied to determine antimicrobial activity. In the study, the antioxidant activity value of H. persicum was determined as 5.36 mg mL-1, the total phenolic content was 20.84 mg GAE mL-1 and the total flavonoid content was 12.35 mg QE mL-1. The plant's inhibition against lipid peroxidation was measured as 3.63 mg mL-1. Its antioxidant activity and inhibitory effect against lipid peroxidation were lower than butylated hydroxyanisole (BHA) in both analyses (p<0.05). The plant extract was found to be effective against Bacillus subtilis, Enterococcus faecalis, Pseudomonas aeruginosa and Staphylococcus aureus bacteria. As a result, the antioxidant properties, antimicrobial and anti-lipid peroxidation effects of H. persicum plant have revealed that this plant has an important potential for use in medicine and pharmacology, as well as for consumption as food.

Anahtar Kelimeler

Kaynakça

  1. Akbaribazm, M., Goodarzi, N., Rahimi, M., Naseri, L., Khazaei, M., 2021. Anti-inflammatory, anti-oxidative and anti-apoptotic effects of Heracleum persicum L. extract on rats with gentamicin-induced nephrotoxicity. Asian Pacific Journal of Tropical Biomedicine, 11(2): 47-58.
  2. Al-Menhali, A.S., Banu, S., Angelova, P.R., Barcaru, A., Horvatovich, P., Abramov, A.Y., Jaganjac, M., 2020. Lipid peroxidation is involved in calcium dependent upregulation of mitochondrial metabolism in skeletal muscle. Biochimica et Biophysica Acta-General Subjects, 1864: 129487.
  3. Araújo, J.S.C., Castilho, A.R.F., Lira, A.B., Pereira, A.V., Azevêdo, T.K.B., Brito Costa, E.M.M., Pereira, M.S.V., Pessôah, H.L.F., Pereira, J.V., 2018. Antibacterial activity against cariogenic bacteria and cytotoxic and genotoxic potential of Anacardium occidentale L. and Anadenanthera macrocarpa (Benth.) Brenan extracts. Archives of Oral Biology, 85: 113-119.
  4. Aruoma, O.I., 2003. Methodological considerations for characterizing potential antioxidant actions of bioactive components in plant foods. Mutation Research, 524: 9-20.
  5. Çoruh, N., Sagdıçoglu Celep, A.G., Özgökçe, F., 2007. Antioxidant properties of Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. and Heracleum persicum Desf. from Apiaceae family used as food in Eastern Anatolia and their inhibitory effects on glutathione-S-transferase. Food Chemistry, 100(3): 1237-1242.
  6. Dehghan, H., Sarrafi, Y., Salehi, P., 2016. Antioxidant and antidiabetic activities of 11 herbal plants from Hyrcania region, Iran. Journal of Food and Drug Analysis, 24(1): 179-188.
  7. Del Rio, D., Rodriguez-Mateos, A., Spencer, J.P.E., Tognolini, M., Borges, G., Crozier, A., 2013. Dietary (poly) phenolics in human health: Structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxidants & Redox Signaling, 18(14): 1818-1892.
  8. Doğan, D., Meydan, İ., 2021. Antioxidant effect of Achillea biebersteinii in different extracts and extinguhishing activity on DPPH. Journal of Agriculture, 4(1): 1-9.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Tıbbi ve Aromatik Bitkiler

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

28 Ağustos 2024

Gönderilme Tarihi

5 Şubat 2024

Kabul Tarihi

14 Ağustos 2024

Yayımlandığı Sayı

Yıl 2024 Cilt: 11 Sayı: 2

Kaynak Göster

APA
Okumuş, E., & Meydan, İ. (2024). Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum. Türkiye Tarımsal Araştırmalar Dergisi, 11(2), 157-163. https://doi.org/10.19159/tutad.1430715
AMA
1.Okumuş E, Meydan İ. Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum. TÜTAD. 2024;11(2):157-163. doi:10.19159/tutad.1430715
Chicago
Okumuş, Emine, ve İsmet Meydan. 2024. “Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum”. Türkiye Tarımsal Araştırmalar Dergisi 11 (2): 157-63. https://doi.org/10.19159/tutad.1430715.
EndNote
Okumuş E, Meydan İ (01 Ağustos 2024) Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum. Türkiye Tarımsal Araştırmalar Dergisi 11 2 157–163.
IEEE
[1]E. Okumuş ve İ. Meydan, “Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum”, TÜTAD, c. 11, sy 2, ss. 157–163, Ağu. 2024, doi: 10.19159/tutad.1430715.
ISNAD
Okumuş, Emine - Meydan, İsmet. “Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum”. Türkiye Tarımsal Araştırmalar Dergisi 11/2 (01 Ağustos 2024): 157-163. https://doi.org/10.19159/tutad.1430715.
JAMA
1.Okumuş E, Meydan İ. Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum. TÜTAD. 2024;11:157–163.
MLA
Okumuş, Emine, ve İsmet Meydan. “Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum”. Türkiye Tarımsal Araştırmalar Dergisi, c. 11, sy 2, Ağustos 2024, ss. 157-63, doi:10.19159/tutad.1430715.
Vancouver
1.Emine Okumuş, İsmet Meydan. Antioxidant, Anti-Lipid Peroxidation and Antimicrobial Effect of Heracleum persicum. TÜTAD. 01 Ağustos 2024;11(2):157-63. doi:10.19159/tutad.1430715

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