EN
TR
Chemoradiotherapy in the Head and Neck Squamous Cell Cancer
Öz
The treatment of head and neck squmaous cell cancer (HNSSC) requires a multidisciplinary management. Postoperative chemoradiotherapy (CRT) has been the gold standart in the patients with early stage HNSSC with poor prognostic factors. The treatment of locally advanced HNSSC includes surgery and adjuvant CRT, induction chemotherapy followed by definitive CRT or CRT alone. Induction chemotherapy followed by definitive CRT has been a successful approach for organ preservation, in particularly operable HNSSC. It has been demonstrated that the greatest survival benefit over radiotherapy (RT) alone is seen with the CRT in several trials. Specifically, to improve the efficacy of the treatment for organ preservation, it has been explored new induction combination regimens with taxanes and found to be more efficient comparing with the cisplatin-5 fluorouracil regimens. The favorable efficiency of the concomitantly usage of taxans with RT, has been demonstrated in only Phase II studies. More recently, the improving efficacy of epidermal growth factor receptor inhibitor (Cetuximab) combined with RT has been determined on survival in several trials. In this review, we overviewed the current literatures within the future role of new agents on the base of clinical trials.
Anahtar Kelimeler
Ayrıntılar
Birincil Dil
İngilizce
Konular
-
Bölüm
-
Yayımlanma Tarihi
1 Mart 2011
Gönderilme Tarihi
1 Mart 2011
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2011 Cilt: 37 Sayı: 1
APA
Demiröz, C., & Özşahin, E. M. (2011). Chemoradiotherapy in the Head and Neck Squamous Cell Cancer. Journal of Uludağ University Medical Faculty, 37(1), 61-65. https://izlik.org/JA48HE24PH
AMA
1.Demiröz C, Özşahin EM. Chemoradiotherapy in the Head and Neck Squamous Cell Cancer. Uludağ Tıp Derg. 2011;37(1):61-65. https://izlik.org/JA48HE24PH
Chicago
Demiröz, Candan, ve Esat Mahmut Özşahin. 2011. “Chemoradiotherapy in the Head and Neck Squamous Cell Cancer”. Journal of Uludağ University Medical Faculty 37 (1): 61-65. https://izlik.org/JA48HE24PH.
EndNote
Demiröz C, Özşahin EM (01 Mart 2011) Chemoradiotherapy in the Head and Neck Squamous Cell Cancer. Journal of Uludağ University Medical Faculty 37 1 61–65.
IEEE
[1]C. Demiröz ve E. M. Özşahin, “Chemoradiotherapy in the Head and Neck Squamous Cell Cancer”, Uludağ Tıp Derg, c. 37, sy 1, ss. 61–65, Mar. 2011, [çevrimiçi]. Erişim adresi: https://izlik.org/JA48HE24PH
ISNAD
Demiröz, Candan - Özşahin, Esat Mahmut. “Chemoradiotherapy in the Head and Neck Squamous Cell Cancer”. Journal of Uludağ University Medical Faculty 37/1 (01 Mart 2011): 61-65. https://izlik.org/JA48HE24PH.
JAMA
1.Demiröz C, Özşahin EM. Chemoradiotherapy in the Head and Neck Squamous Cell Cancer. Uludağ Tıp Derg. 2011;37:61–65.
MLA
Demiröz, Candan, ve Esat Mahmut Özşahin. “Chemoradiotherapy in the Head and Neck Squamous Cell Cancer”. Journal of Uludağ University Medical Faculty, c. 37, sy 1, Mart 2011, ss. 61-65, https://izlik.org/JA48HE24PH.
Vancouver
1.Candan Demiröz, Esat Mahmut Özşahin. Chemoradiotherapy in the Head and Neck Squamous Cell Cancer. Uludağ Tıp Derg [Internet]. 01 Mart 2011;37(1):61-5. Erişim adresi: https://izlik.org/JA48HE24PH
