İntraperitonal Diklorvos Uygulamasının Sıçanların (Rattus norvegicus) Bazı Dokularında Glukoz 6-Fosfat Dehidrogenaz ve Malat Dehidrogenaz Aktiviteleri Üzerine Etkisi

Cilt: 33 Sayı: 1 1 Mart 2007
  • Egemen Dere
  • Ferda Özdikicioğlu
  • Hakan Tosunoğlu
PDF İndir
EN TR

The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus)

Öz

In this study, rats (Rattus norvegicus) were intraperitoneally injected with 4 mg kg-1 dose of dichlorvos (DDVP), a toxic agent widely used for agricultural purposes. Physiological saline was administered to each control group. Changes in the glucose 6-phosphate dehydrogenase (G6PD) and malate dehydrogenase (MDH) activities in the liver, kidney, brain and small intestine of male and female rats were investigated at 0, 2, 4, 8, 16, 32, 64 and 72 hours following injection. Enzyme activities were measured spectrophotometrically. Statistical analysis was performed using the SPSS program. As a result, dichlorvos which primarily inhibits acetylcholinesterase (AChE) activity in the nervous system causes significant (p<0.05) changes in both enzyme activities in studied tissues of male and female rats.

Anahtar Kelimeler

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Egemen Dere Bu kişi benim

Ferda Özdikicioğlu Bu kişi benim

Hakan Tosunoğlu Bu kişi benim

Yayımlanma Tarihi

1 Mart 2007

Gönderilme Tarihi

1 Mart 2007

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2007 Cilt: 33 Sayı: 1

Kaynak Göster

APA
Dere, E., Özdikicioğlu, F., & Tosunoğlu, H. (2007). The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus). Journal of Uludağ University Medical Faculty, 33(1), 5-10. https://izlik.org/JA23AS66LB
AMA
1.Dere E, Özdikicioğlu F, Tosunoğlu H. The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus). Uludağ Tıp Derg. 2007;33(1):5-10. https://izlik.org/JA23AS66LB
Chicago
Dere, Egemen, Ferda Özdikicioğlu, ve Hakan Tosunoğlu. 2007. “The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus)”. Journal of Uludağ University Medical Faculty 33 (1): 5-10. https://izlik.org/JA23AS66LB.
EndNote
Dere E, Özdikicioğlu F, Tosunoğlu H (01 Mart 2007) The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus). Journal of Uludağ University Medical Faculty 33 1 5–10.
IEEE
[1]E. Dere, F. Özdikicioğlu, ve H. Tosunoğlu, “The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus)”, Uludağ Tıp Derg, c. 33, sy 1, ss. 5–10, Mar. 2007, [çevrimiçi]. Erişim adresi: https://izlik.org/JA23AS66LB
ISNAD
Dere, Egemen - Özdikicioğlu, Ferda - Tosunoğlu, Hakan. “The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus)”. Journal of Uludağ University Medical Faculty 33/1 (01 Mart 2007): 5-10. https://izlik.org/JA23AS66LB.
JAMA
1.Dere E, Özdikicioğlu F, Tosunoğlu H. The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus). Uludağ Tıp Derg. 2007;33:5–10.
MLA
Dere, Egemen, vd. “The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus)”. Journal of Uludağ University Medical Faculty, c. 33, sy 1, Mart 2007, ss. 5-10, https://izlik.org/JA23AS66LB.
Vancouver
1.Egemen Dere, Ferda Özdikicioğlu, Hakan Tosunoğlu. The Effect of Intraperitoneal Administration of Dichlorvos on The Activity Glucose 6-Phosphate Dehydrogenase and Malate Dehydrogenase in Some Tissues of Rats (Rattus norvegicus). Uludağ Tıp Derg [Internet]. 01 Mart 2007;33(1):5-10. Erişim adresi: https://izlik.org/JA23AS66LB

ISSN: 1300-414X, e-ISSN: 2645-9027

Uludağ Üniversitesi Tıp Fakültesi Dergisi "Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License" ile lisanslanmaktadır.


Creative Commons License
Journal of Uludag University Medical Faculty is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

2023