Lokal İleri ve Metastatik Mide Kanserli Hastalarda Tedavi Öncesi AFP, CEA ve CA 19-9 Serum Seviyeleri ile Klinikopatolojik Faktörlerin Arasındaki İlişki

Cilt: 37 Sayı: 3 1 Eylül 2011
  • Muharrem Bayrak
  • Ömer Fatih Ölmez
  • Ender Kurt
  • Erdem Çubukcu
  • Nilüfer Avcı
  • Sinem Çubukcu
  • Pınar Söker
  • Osman Manavoğlu
Uludağ Üniversitesi Tıp Fakültesi Dergisi Kapak
Uludağ Üniversitesi Tıp Fakültesi Dergisi
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The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer

Öz

Pre-treatment serum levels of AFP, CEA and CA 19-9 were retrospectively investigated in 70 patients with locally advanced and metastatic gastric cancer. The positivity rates for these markers were 55.7%, 40% and 32.9%, respectively. Multiple logistic regression analysis for positive levels of tumor markers indicates that AFP positivity is significantly related to the presence of hepatic metastasis and resectability rates (p=0.041), CEA positivity is related to advance stage (p=0.011), tumor size (p=0.004), presence of hepatic metastasis (p=0.001), the frequency of serosal invasion (p=0.004) and resectability rates (p=0.011). Finally, CA 19-9 positivity is related to advance stage (p=0.006), tumor size (p=0.002), the frequency of serosal invasion (p=0.002), the frequency of peritoneal metastasis (p=0.005) and ascites (p=0.005). In summary, in cancer patients, the use of tumor markers for the decision of treatment might indicate the existence of any organ metastasis which could not be clinically or radiologically revealed.

Anahtar Kelimeler

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Muharrem Bayrak Bu kişi benim

Ömer Fatih Ölmez Bu kişi benim

Ender Kurt Bu kişi benim

Erdem Çubukcu Bu kişi benim

Nilüfer Avcı Bu kişi benim

Sinem Çubukcu Bu kişi benim

Pınar Söker Bu kişi benim

Osman Manavoğlu Bu kişi benim

Yayımlanma Tarihi

1 Eylül 2011

Gönderilme Tarihi

1 Eylül 2011

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2011 Cilt: 37 Sayı: 3

IZ

https://izlik.org/JA79SP53BE

Kaynak Göster

RIS / Bibtex
APA
Bayrak, M., Ölmez, Ö. F., Kurt, E., Çubukcu, E., Avcı, N., Çubukcu, S., Söker, P., & Manavoğlu, O. (2011). The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer. Journal of Uludağ University Medical Faculty, 37(3), 139-143. https://izlik.org/JA79SP53BE
AMA
1.Bayrak M, Ölmez ÖF, Kurt E, vd. The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer. Uludağ Tıp Derg. 2011;37(3):139-143. https://izlik.org/JA79SP53BE
Chicago
Bayrak, Muharrem, Ömer Fatih Ölmez, Ender Kurt, vd. 2011. “The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer”. Journal of Uludağ University Medical Faculty 37 (3): 139-43. https://izlik.org/JA79SP53BE.
EndNote
Bayrak M, Ölmez ÖF, Kurt E, Çubukcu E, Avcı N, Çubukcu S, Söker P, Manavoğlu O (01 Eylül 2011) The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer. Journal of Uludağ University Medical Faculty 37 3 139–143.
IEEE
[1]M. Bayrak vd., “The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer”, Uludağ Tıp Derg, c. 37, sy 3, ss. 139–143, Eyl. 2011, [çevrimiçi]. Erişim adresi: https://izlik.org/JA79SP53BE
ISNAD
Bayrak, Muharrem - Ölmez, Ömer Fatih - Kurt, Ender - Çubukcu, Erdem - Avcı, Nilüfer - Çubukcu, Sinem - Söker, Pınar - Manavoğlu, Osman. “The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer”. Journal of Uludağ University Medical Faculty 37/3 (01 Eylül 2011): 139-143. https://izlik.org/JA79SP53BE.
JAMA
1.Bayrak M, Ölmez ÖF, Kurt E, Çubukcu E, Avcı N, Çubukcu S, Söker P, Manavoğlu O. The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer. Uludağ Tıp Derg. 2011;37:139–143.
MLA
Bayrak, Muharrem, vd. “The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer”. Journal of Uludağ University Medical Faculty, c. 37, sy 3, Eylül 2011, ss. 139-43, https://izlik.org/JA79SP53BE.
Vancouver
1.Muharrem Bayrak, Ömer Fatih Ölmez, Ender Kurt, Erdem Çubukcu, Nilüfer Avcı, Sinem Çubukcu, Pınar Söker, Osman Manavoğlu. The Relationship Between Pre-treatment Serum Levels of AFP, CEA and CA 19-9 and Clinicopathological Factors in Patients with Locally Advanced and Metastatic Gastric Cancer. Uludağ Tıp Derg [Internet]. 01 Eylül 2011;37(3):139-43. Erişim adresi: https://izlik.org/JA79SP53BE

ISSN: 1300-414X, e-ISSN: 2645-9027

Uludağ Üniversitesi Tıp Fakültesi Dergisi "Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License" ile lisanslanmaktadır.


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Journal of Uludag University Medical Faculty is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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