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Lipomas of the Gastrointestinal Tract: Retrospective Analysis of 19 Cases

Yıl 2021, Cilt: 47 Sayı: 2, 273 - 277, 01.08.2021
https://doi.org/10.32708/uutfd.916205

Öz

Abstract
In this descriptive study, we aimed to present lipoma cases diagnosed in the gastrointestinal tract and to evaluate the clinicopathological features of these tumors based on literature review. In this study, patient files of 19 cases diagnosed with lipoma of the gastrointestinal tract between 2006 and 2018 were retrospectively reviewed from the archives of the Department of Pathology of Faculty of Medicine. Seventeen cases with lipoma of the gastrointestinal tract were diagnosed between 2006 and 2018. Eleven of the cases were female (%57,9), and eight (42,1%) were male. The mean age of the patients was 62,3 years (range: 36-78 years). Of the 17 cases, 14 were located in the colon, 3 in the small intestine and 1 in the stomach. The classical morphology of lipoma was seen in all cases except one case that was diagnosed with angiolipoma located in the descending colon. Generally, incidentally detected lipomas, which can be accompanied by adenocarcinomas, are tumors that can lead to gastrointestinal symptoms such as obstruction, intussusception and bleeding, and differential diagnosis of malignancies is required. All cases should be examined by appropriate radiological and endoscopic methods before operation and the most appropriate treatment option should be evaluated for each case.

Kaynakça

  • Kang HC, Menias CO, Gaballah AH, Shroff S, Taggart MW, Garg N, Elsayes KM. Beyond the GIST: mesenchymal tumors of the stomach. Radiographics. 2013 Oct;33(6):1673-90. doi: 10.1148/rg.336135507.
  • Tascilar O, Cakmak GK, Gun BD, Ucan AH, Balbaloglu H, Cesur A, Emre AU, Comert M, Erdem LO, Aydemir S. Clinical evaluation of submucosal colonic lipomas: decision making. World J Gastroenterol. 2006 Aug 21;12(31):5075-7.
  • Chung Y, Ho Y, Nyam D, et al: Management of colonic lipomas. Aust NZ J Surg 68:133-5, 1998.
  • Gould DJ, Anne Morrison C, Liscum KR, Silberfein EJ. A lipoma of the transverse colon causing intermittent obstruction: a rare cause for surgical intervention. Gastroenterol Hepatol (N Y). 2011 Jul;7(7):487-90.
  • Aytaç B, Yerci Ö, Gürel S, Ferik Z. Colonic Lipomas Mimicking Colon Cancer. Turk Patoloji Derg. 2010,26(3):196-9.
  • Zhang H, Cong JC, Chen CS, Qiao L, Liu EQ. Submucous colon lipoma: a case report and review of the literature. World J Gastroenterol. 2005 May 28;11(20):3167-9.
  • Chehade HH, Zbibo RH, Nasreddine W, Abtar HK. Large ileocecal submucosal lipoma presenting as hematochezia, a case report and review of literature. Int J Surg Case Rep. 2015;10:1-4.
  • Eryılmaz MA, Yücel A, Yücel H, Arıcıgil M. Cervico-Thoracic Giant Lipoma in a Child. Turk Arch Otorhinolaryngol. 2016 Jun;54(2):82-85. doi: 10.5152/tao.2016.1620. Epub 2016 Jun 1.
  • Thompson WM. Imaging and findings of lipomas of the gastrointestinal tract. AJR Am J Roentgenol. 2005 Apr;184(4):1163-71.
  • Dassanayake SUB, Dinamithra NP, Nawarathne NMM. Submucosal lipoma of the sigmoid colon as a rare cause of mucoid diarrhea: a case report. J Med Case Rep. 2016 Jan 20;10:17.
  • Narindra Rajaonarison Ny Ony L, Ahmad A, Bruneton JN. Lipomas of the digestive tract: General aspects and imaging. Cureus. 2014 September;6(9): e208.
  • Lin Y, Chiu N, Li AF, Liu C, Chou Y, Chiou Y. Unusual gastric tumors and tumor-like lesions: Radiological with pathological correlation and literature review. World J Gastroenterol 2017 April 14; 23(14): 2493-2504.
  • Val-Bernal JF, Hermana S, Gómez-Román JJ. Incidental, low-fat variant of spindle cell lipoma: a novel tumour of the small intestine. Pol J Pathol. 2018;69(1):82-86. doi: 10.5114/pjp.2018.75341.
  • Jiang L, Jiang LS, Li FY, Ye H, Li N, Cheng NS, Zhou Y. Giant submucosal lipoma located in the descending colon: a case report and review of the literature. World J Gastroenterol. 2007 Nov 14;13(42):5664-7.
  • Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F. World Health Organization Classification of Tumours of Soft Tissue and Bone: Adipocytic tumors 4th ed. Lyon, France: IARC Press, 2013; 20-43.
  • Fisher C, Montgomery EA, Thway K. Bıopsy Interpretation Series Biopsy Interpretation of the Soft tissue tumors. 2th ed. Philadelphia;2011. 355-402.
  • Henderson-Jackson EB, Bui MM. Molecular Pathology of Soft-Tissue Neoplasms and Its Role in Clinical Practice. Cancer Control. 2015 Apr;22(2):186-92.
  • El-Dika S, Vahabzadeh A, Karageorge L, Kinsey A. A large pedunculated lipoma endoscopically resected with the assistance of a detachable nylon endoloop. Gastroenterol Hepatol (N Y). 2007 Nov;3(11):880-1.
  • Namikawa T, Munekage E, Mizuta H, Kobayashi M, Saibara T, Hanazaki K. Simultaneous occurrence of gastric lipoma and early gastric cancer. Endoscopy. 2014;46 Suppl 1 UCTN:E338

Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi

Yıl 2021, Cilt: 47 Sayı: 2, 273 - 277, 01.08.2021
https://doi.org/10.32708/uutfd.916205

Öz

Özet
Bu tanımlayıcı çalışmada gastrointestinal sistem yerleşimli lipoma tanılı olgularının sunulması ve bu tümörlerin klinikopatolojik özelliklerinin literatür bilgileri eşliğinde değerlendirilmesini amaçlanmıştır. Çalışmamızda Tıbbi Patoloji Anabilim Dalı arşivi taranarak gastrointestinal sistem yerleşimli lipoma tanılı 19 olgu retrospektif olarak incelendi. Gastrointestinal sistem yerleşimli lipoma tanısı almış toplam 19 olgu tespit edildi. Olguların 11'i kadın (%57,9), 8'i erkekti (%42,1). Olguların yaş dağılımı 36-78 yaş arasında değişmekte olup, ortalama yaş değeri 62,3+9 yaş olarak saptandı. 19 olgunun 1'i mide, 3'ü ince barsak, 14’ü kolon ve 1'i rektum yerleşimliydi. Angiolipoma tanısı alan inen kolon yerleşimli tek olgu dışında kalan tüm olgular klasik lipoma morfolojsindeydi. Genellikle insidental olarak saptanan lipomalar, obtrüksiyon, intrususepsiyon ve kanama gibi ciddid gastrointestinal semptomlara yol açabilen, adenokarsinomalara eşlik edebilen ve malignitelerle ayırıcı tanısı yapılması gereken tümörlerdir. Tüm olgular operasyon öncesinde uygun radyolojik ve endoskopik yöntemlerle incelenmeli ve her olgu için en uygun tedavi seçeneği değerlendirilmelidir.

Kaynakça

  • Kang HC, Menias CO, Gaballah AH, Shroff S, Taggart MW, Garg N, Elsayes KM. Beyond the GIST: mesenchymal tumors of the stomach. Radiographics. 2013 Oct;33(6):1673-90. doi: 10.1148/rg.336135507.
  • Tascilar O, Cakmak GK, Gun BD, Ucan AH, Balbaloglu H, Cesur A, Emre AU, Comert M, Erdem LO, Aydemir S. Clinical evaluation of submucosal colonic lipomas: decision making. World J Gastroenterol. 2006 Aug 21;12(31):5075-7.
  • Chung Y, Ho Y, Nyam D, et al: Management of colonic lipomas. Aust NZ J Surg 68:133-5, 1998.
  • Gould DJ, Anne Morrison C, Liscum KR, Silberfein EJ. A lipoma of the transverse colon causing intermittent obstruction: a rare cause for surgical intervention. Gastroenterol Hepatol (N Y). 2011 Jul;7(7):487-90.
  • Aytaç B, Yerci Ö, Gürel S, Ferik Z. Colonic Lipomas Mimicking Colon Cancer. Turk Patoloji Derg. 2010,26(3):196-9.
  • Zhang H, Cong JC, Chen CS, Qiao L, Liu EQ. Submucous colon lipoma: a case report and review of the literature. World J Gastroenterol. 2005 May 28;11(20):3167-9.
  • Chehade HH, Zbibo RH, Nasreddine W, Abtar HK. Large ileocecal submucosal lipoma presenting as hematochezia, a case report and review of literature. Int J Surg Case Rep. 2015;10:1-4.
  • Eryılmaz MA, Yücel A, Yücel H, Arıcıgil M. Cervico-Thoracic Giant Lipoma in a Child. Turk Arch Otorhinolaryngol. 2016 Jun;54(2):82-85. doi: 10.5152/tao.2016.1620. Epub 2016 Jun 1.
  • Thompson WM. Imaging and findings of lipomas of the gastrointestinal tract. AJR Am J Roentgenol. 2005 Apr;184(4):1163-71.
  • Dassanayake SUB, Dinamithra NP, Nawarathne NMM. Submucosal lipoma of the sigmoid colon as a rare cause of mucoid diarrhea: a case report. J Med Case Rep. 2016 Jan 20;10:17.
  • Narindra Rajaonarison Ny Ony L, Ahmad A, Bruneton JN. Lipomas of the digestive tract: General aspects and imaging. Cureus. 2014 September;6(9): e208.
  • Lin Y, Chiu N, Li AF, Liu C, Chou Y, Chiou Y. Unusual gastric tumors and tumor-like lesions: Radiological with pathological correlation and literature review. World J Gastroenterol 2017 April 14; 23(14): 2493-2504.
  • Val-Bernal JF, Hermana S, Gómez-Román JJ. Incidental, low-fat variant of spindle cell lipoma: a novel tumour of the small intestine. Pol J Pathol. 2018;69(1):82-86. doi: 10.5114/pjp.2018.75341.
  • Jiang L, Jiang LS, Li FY, Ye H, Li N, Cheng NS, Zhou Y. Giant submucosal lipoma located in the descending colon: a case report and review of the literature. World J Gastroenterol. 2007 Nov 14;13(42):5664-7.
  • Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F. World Health Organization Classification of Tumours of Soft Tissue and Bone: Adipocytic tumors 4th ed. Lyon, France: IARC Press, 2013; 20-43.
  • Fisher C, Montgomery EA, Thway K. Bıopsy Interpretation Series Biopsy Interpretation of the Soft tissue tumors. 2th ed. Philadelphia;2011. 355-402.
  • Henderson-Jackson EB, Bui MM. Molecular Pathology of Soft-Tissue Neoplasms and Its Role in Clinical Practice. Cancer Control. 2015 Apr;22(2):186-92.
  • El-Dika S, Vahabzadeh A, Karageorge L, Kinsey A. A large pedunculated lipoma endoscopically resected with the assistance of a detachable nylon endoloop. Gastroenterol Hepatol (N Y). 2007 Nov;3(11):880-1.
  • Namikawa T, Munekage E, Mizuta H, Kobayashi M, Saibara T, Hanazaki K. Simultaneous occurrence of gastric lipoma and early gastric cancer. Endoscopy. 2014;46 Suppl 1 UCTN:E338
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Patoloji
Bölüm Özgün Araştırma Makaleleri
Yazarlar

Mine Özşen 0000-0002-5771-7649

Ömer Yerci 0000-0001-7118-5258

Nesrin Uğraş 0000-0003-0127-548X

Özgen Işık Bu kişi benim 0000-0002-9541-5035

Tuncay Yılmazlar Bu kişi benim 0000-0003-1924-0795

Yayımlanma Tarihi 1 Ağustos 2021
Kabul Tarihi 26 Ağustos 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 47 Sayı: 2

Kaynak Göster

APA Özşen, M., Yerci, Ö., Uğraş, N., Işık, Ö., vd. (2021). Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 47(2), 273-277. https://doi.org/10.32708/uutfd.916205
AMA Özşen M, Yerci Ö, Uğraş N, Işık Ö, Yılmazlar T. Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi. Uludağ Tıp Derg. Ağustos 2021;47(2):273-277. doi:10.32708/uutfd.916205
Chicago Özşen, Mine, Ömer Yerci, Nesrin Uğraş, Özgen Işık, ve Tuncay Yılmazlar. “Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi 47, sy. 2 (Ağustos 2021): 273-77. https://doi.org/10.32708/uutfd.916205.
EndNote Özşen M, Yerci Ö, Uğraş N, Işık Ö, Yılmazlar T (01 Ağustos 2021) Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi. Uludağ Üniversitesi Tıp Fakültesi Dergisi 47 2 273–277.
IEEE M. Özşen, Ö. Yerci, N. Uğraş, Ö. Işık, ve T. Yılmazlar, “Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi”, Uludağ Tıp Derg, c. 47, sy. 2, ss. 273–277, 2021, doi: 10.32708/uutfd.916205.
ISNAD Özşen, Mine vd. “Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi 47/2 (Ağustos 2021), 273-277. https://doi.org/10.32708/uutfd.916205.
JAMA Özşen M, Yerci Ö, Uğraş N, Işık Ö, Yılmazlar T. Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi. Uludağ Tıp Derg. 2021;47:273–277.
MLA Özşen, Mine vd. “Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi, c. 47, sy. 2, 2021, ss. 273-7, doi:10.32708/uutfd.916205.
Vancouver Özşen M, Yerci Ö, Uğraş N, Işık Ö, Yılmazlar T. Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi. Uludağ Tıp Derg. 2021;47(2):273-7.

ISSN: 1300-414X, e-ISSN: 2645-9027

Uludağ Üniversitesi Tıp Fakültesi Dergisi "Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License" ile lisanslanmaktadır.


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Journal of Uludag University Medical Faculty is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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