The significance of serum uric acid levels in hypertensive diseases of pregnancy

Abstract

Objective: Our purpose was to evaluate if uric acid levels at hypertensive diseases of pregnancy has clinical utility on severity of preeclampsia and perinatal prognosis. Material - Method: 267 patients whose serum uric acid levels have been measured during 3rd trimester of pregnancy were involved in our study. These patients have been examined under four groups. These groups were; control (n=110), mild preeclampsia (n=68), severe preeclampsia (n=72) and chronic hypertension (n=17). Average serum uric acid levels, age, gravida, parity, abortion, live birth, gestational week, birth weight, hemoglobin, hematocrit and platelet levels have been compared between all groups by using GraphPadPrisma V.3 packet program. Results: Comparing mild preeclampsia and severe preeclampsia groups seperately with the control group according to avarage serum uric acid levels, serious diversity has been found (p0,05 ). When severe and mild preeclampsia groups have been compared with each other according to serum uric acid levels, distinction was statistically meaningful (p

Keywords

• Pregnancy Trimester, Third,Uric Acid,Pre-Eclampsia,Hypertension

Gebeliğin hipertansif hastalıklarında serum ürik asit seviyelerinin önemi

Öz

Amaç: Gebelerin hipertansif hastalıklarında ürik asit düzeylerinin, hastalığın ağırlığı ve perinatal sonuçları hakkında klinik öneminin olup olmadığının araştırılması. Materyal ve Metod: Çalışmamıza serum ürik asit düzeyleri 3. trimester içinde ölçülen 267 olgu alındı. Bu olgular toplam dört grupta incelendi. Bu gruplar kontrol (n=110), hafif preeklampsi (n=68), ağır preeklampsi (n=72) ve kronik hipertansiyon (n=17) olarak oluşturuldu. Bütün gruplar arasında ortalama serum ürik asit düzeyleri, yaş, gravida, parite, abortus, yaşayan çocuk, gestasyonel hafta, doğum kilosu, hemoglobin, hematokrit ve trombosit düzeyleri Graph PadPrisma V3 paket programı kullanılarak karşılaş tırıldı. Bulgular: Kontrol grubu ile hafif ve ağır preeklampsi grupları, ortalama serum ürik asit düzeylerine göre ayn ayrı kıyaslan dığında, önemli derecede farklılık saptandı (p0,05). Ağır ve hafif preeklampsi grupları serum ürik asit düzeyleri açısından kendi aralarında kıyas landığında ise, istatistiki yönden fark anlamlıydı (p

Anahtar Kelimeler

• Gebelik trimester, üçüncü,Ürik asit,Preeklampsi,Hipertansiyon

Kaynakça

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