Current management and transfusion products during pregnancy

Öz

Transfusion guidelines in the obstetric patient are difficult to define and even more difficult to standardize. Both maternal and fetal factors need to be evaluated. It is estimated that between 0.4 to 1.6% of pregnancies result in transfusion. The practice of obstetrics and transfusion medicine has advanced lately. This article focuses on the unique aspects of current transfusion practice in obstetrics.

Anahtar Kelimeler

• Pregnancy,Blood Transfusion,Blood Component Transfusion,Plasma

Gebelikte kullanılan transfüzyon ürünleri ve son gelişmeler

Öz

Gebelikte transfüzyon metotlarını standardize etmek güçtür ve hem annenin hem de fetüsun değerlendirilmesi şarttır. Gebelikte ve doğum sırasında transfüzyon oranı %0.4 %1.6 arasında gerçekleşmektedir. Bu konuda son yıllarda gelişmeler yaşanmıştır. Bu yazıda doğum ve transfüzyon ile ilgili bu gelişmelerin yanı sıra özellikli bazı konulara değinilmiştir.

Anahtar Kelimeler

• Gebelik,Kan nakli,Kan bileşenleri nakli,Plazma

Kaynakça

1. Combs CA, Murphy EL, Laros RK. Cost- benefitanalysis of autologous blood donation in obstetrics. Obstet Gynecol 1992;80:661-664 Klapholz H. Blood transfusion in contemparary obstetric practice. Obstet Gynecol 1990 ;75:940-943 Ross A, Malkoutzis E. Blood transfusion practice in obstetric and gynecological anaesthesia. Anaesthesia and Intensive Care 1995 ;23:645-646 Petersen LA, Lindner DS, Kleiber CM, Zimmerman MB,Hinton AT, Yankowitz J
2. Factors that predict low hematocrit levels in the postpartum patient after vaginal delivery
3. Am J Obstet Gynecol 2002; 186:737-4
4. Ekeroma AJ, Ansari A, Stirrat GM.Blood transfusion in obstetrics and gynecology. British J Obstet Gynecol 1997-,104:278-284 Sirchia G, Giovanetti AM, McClelland DBL, Fracchia GN, editörler. Safe and Good Use of Blood in Surgery (SANGUIS). Europian Commission, 1994
5. Sherman SJ, Greenspoon JS, Nelson JM, Paul RH. Obstetric hemorrage and blood utilization. J Reprod Med 1993;38:929-934 Petz Swisher editör. Clinical Practice of Transfusion Medicine. Üçüncü baskısı
6. Churchill Livingstone. Bölüm yazarı Boy d ME
7. Transfusion Therapy in Obstetrics and Gynecology 1996;583-593 Duthie SJ, Ven D, Yung GL. Discrepency between laboratory determination and visual estimation of blood loss during normal delivery
8. Eur J Obstet Gynecol Redrod Biol 1991 ;38:119- 124 Westphal RG. Transfusion Medicine. Üçüncü baskı, American Red Cross. 1996;99-101 Alving B, Alcorn K. How to improve transfusion medicine. Arch Pathol Lab Med 1999 ;39:1227-1234 Kirkland HE, Mohler DN, Horwitz DA. Inhibition of suppressor lymphocyte function. N Eng J Med 1980;302:825-832 George JN, Nurden AT, Philips DR. Molecular defects in interaction of platelets with the vessel wall. N Eng J Med 1984,-311:1084-1095 Figueroa M, Gehlsen J, Haammond D. Combination chemotherapy in immune trombocytopenic pur pur a. N Eng J Med 1993-,328:1226-1229 Rudolph R, Boyd CR. Massive transfusion South Med J 1990;83:1065-1070 Kruskall MS, Mintz PD, Bergin JJ. Transfusion therapy in emergency medicine. Ann Emerg Med 1988;17-.327:335 Beutler F. Platelet transfusion. Blood 1993;81:1411-1413 Rock GA, Shumak KH, Buskard NH. Comparison of plasma Exchange with plasma infusion in the treatment of trombotic thrombocytopenic purpura. N Eng J Med 1991 ;325:393-397 Harkness DR, Byrness JJ, Lion ECY. Hazard of platelet transfusion in trombotic thrombocytopenic purpura. JAMA 1981,-246:1931-1933 McCrae KR, Samuels P, Schriber AD. Pregnancy associated thrombocytopenia. Blood 1992,-80:2697-2714 Petha JC. Clinical studies with solvent detergent-treated products. Transfusion Med Rev 1996;10:303-311 Perpvia A. Cost effectiveness of transfusing virus-inactivated plasma instead of standart plasma. Transfusion. 1999;39:479-487 Williamson LM, Llewelyn CA, Fisher NC. A randomized trial of solvent/deter gant treated and standart fresh-forzen plasma in the coagulopathy of liver disease and liver transplantation. Transfusion 1999:39:1227-1234 Mast AE, Standanlick JE, Lockett JM, Kietzen DJ. Solvent/detergent treated plasma has decreased antitrypsin activity and absent antiplasmin activity. Blood 1999 ;94:3922-3927 Jacson BR, AuBuchon JP, Birkmeyer JD. Update of cost-effectiveness analysis for soolvet-detergent-treated plasma. JAMA 1999:282:329 Sacks G, Sargent I, Redman C. An innate view of human pregnancy. Immunol Today 1999:20:144-118 Alexender TS, Lee J, Yen-Lieberman B. Incidence of HIV antibody in a prenatal population ata community hospital. Clin Diagn Lab Immunol 1999:6:140-141 Kruskall MS. The safety and utility of autologous donations by pregnant patients. Pro Transfusion 1990 ;30-1 68-171 Sandler SG, Beyth Y, Laufer N, Levene C. Autologous blood transfusion and pregnancy. Obstet Gynecol 1979;53(Suppl):62S-66S Kruskall MS, Leonard S, Klapholz H. Autologous blood donation during pregnancy: analysis of safety and blood use. Obstet Gynecol 1987:70:938-41

9. McShane PM, Heyl PS, Epstein MF. Maternal and perinatal mortality resulting from plecenta previa. Obstet Gynecol 1985 ;65:176-177 Druzin ML, Wolf CFW, Edersheim TG, Hotson JM, KogutJM, Salomon JLN. Donation of blood by the pregnant patient for autologous transfusion. Am J Obstet Gynecol 1988:159:1023-1027 Herbert WNP, Owen HG, Collins ML. Autologous blood storage in obstetrics. Obstet Gynecol 1988:72:166-170