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Yıl 2007, Cilt 38, Sayı 4, 143 - 150, 01.05.2007

Öz

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Kaynakça

  • 1. Ego, A., Subtil, D., Cosson, M., Legoueff, F.O., Houfflin-Debarge, V.R., Querleu,D., Survival analysis of fertility after ectopic Pregnancy, Fertility and Sterility, 75 (3), 2001
  • 2. Grainger, D.A., Seifer, D.B., Laparoscopic management of ectopic pregnancy, Current Opinion Obstet Gynecol, 7, 277-282, 1995
  • 3. Buster, J.E., Carson, S.A., Ectopic pregnancy: new advances in diagnosis and treatment, Current Opinion Obstet Gynecol Scand., 73, 746 - 752, 1994
  • 4. Gleicher, N., Barad, D., Unexplained infertility: does it really exist?, Hum Reprod., 21, 1951-1955, 2006
  • 5. Keay, S.D., Liversedge, N.H., Mathur, R.S. and Jenkins, J.M.Assisted conception following poor ovarian response to gonadotrophin stimulation, Br J Obstet Gynecol., 104, 521-527, 1997
  • 6. Tarlatzis, B.C., Zepiridis, L., Grimbizis, G. and Bontis, J., Clinical management of low ovarian response to stimulation for IVF: a systematic review. Hum Reprod Update, 9, 61-76, 2003
  • 7. Lass, A., Ellenbogen, A., Croucher, C., Trew, G., Margara R., Becattini, C., Winston R.M.L.,Effect of salpingectomy on ovarian response to superovulation in an in vitrofertilization-embryo transfer program, Fertility and Sterility, 70 (6), 1035-1038, 1998
  • 8. Guerriero, S., Ajossa, S., Lai, M.P., Risalvato, A., Paoletti, A.M. and Melis, G.B., Clinical applications of colour Doppler energy imaging in the female reproductive tract and pregnancy, Hum Reprod Update, 5, 515-529, 1999
  • 9. Cooper, J.A., White, D.A., Matthay, R.A., Drug-induced pulmonary disease. Part 1: Cytotoxic drugs, Am Rev Respir Dis., 133, 321-340, 1986
  • 10. Orvieto, IVF cycle following MTX therapy, Fertil Steril, 2007. Article in pres
  • 11. Dar, P., Sachs, G.S., Strassburger, D., Bukovsky, I., Arielli, S., Ovarian function before and after salpinjectomy in artificial reproductive technology patients, Hum Reprod., 15 (1), 142-144, 2000
  • 12. Verhulst, G., Vandersteen, N., Van Steirteghem, A.C., Devroey, P., Bilateral salpingectomy does not compromise ovarian stimulation in an in-vitro fertilization/embryo transfer program, Hum Reprod., 9(4), 624-628, 1994
  • 13. Strandell, A., Lindhard, A.,Waldenstrom, U., Thorburn, J., Prophylactic salpingectomy does not impair the ovarian response in IVF treatment, Hum Reprod., 16(6), 1135-1139, 2001
  • 14. Chan C.C.W. ,.Ng, E.H.Y., Li, C.F. and Ho, P.C., Impaired ovarian blood flow and reduced antral follicle count following laparoscopic salpingectomy for ectopic pregnancy, Human Reproduction., 18(10) 2175-2180, 2003
  • 15. KelekciS., Yilmaz, B., Yakut, Y, Yasar, L., Savan, K., Sonmez, S., Hormonal and ovarian stromal blood supply changes after laparoscopic tubal sterilization: a prospective controlled study, Contraception, 73, 279- 283, 2006
  • 16. Sumiala, S., Pirhonen, J., Tuominen, J. and Maenpaa, J., Increased uterine and ovarian vascular resistance following Filshie clip sterilization: preliminary findings obtained with color Doppler ultrasonography, J. Clin. Ultrasound, 23, 511-516, 1995
  • 17. Geber, S. and Caetano, J.P., Doppler colour flow analysis of uterine and ovarian arteries prior to and after surgery for tubal sterilization: a prospective study, Hum. Reprod., 11, 1195-1198, 1996

The changes of the ovarian function after ectopic pregnancy treatment (laparoscopic salpingostomy and systemic methotrexate)

Yıl 2007, Cilt 38, Sayı 4, 143 - 150, 01.05.2007

Öz

The Changes of The Ovarian Function after Ectopic Pregnancy Treatment (Laparoscopic salpingostomy and systemic Methotrexate) Aim: To evaluate the changes of the ovarian function inpatients with ectopic pregnancy treated by laparoscopic salpingostomy and systemic single dose methotreaxate. Materials and Methods: This study was included 28 patients with ectopic pregnancy treated by laparoscopic salpingostomy and 14 patients with ectopic pregnancy treated by 50 mg/m2 single dose methotrexate, from January 2005 to July 2007. All patients were evaluated by transvaginal sonography before treatment to determine both ovarian volumes, antral follicle counts and bloodflow characteristics. SPSS for Windows 13.0 was used for statistical analysis. Results: The mean age was 30.6±4.5 in patients treated by laparoscopy, whereas it was 30.07±3.6 in patients treated by methotrexate (p: 0,68). Gravidity and partity were 0,92±1,11 and 0,50 ± 0,63 in patients treated by laparoscopy, whereas they were 0,78 ±0,8 and 0,5 ±0,65 in patients treated by methotrexate respectively. Conclusion: Our results showed that both treatment modalities (laparoscopic salpingostomy and systemic methotreaxate) have no adverse effect on the ovarianfunction.

Kaynakça

  • 1. Ego, A., Subtil, D., Cosson, M., Legoueff, F.O., Houfflin-Debarge, V.R., Querleu,D., Survival analysis of fertility after ectopic Pregnancy, Fertility and Sterility, 75 (3), 2001
  • 2. Grainger, D.A., Seifer, D.B., Laparoscopic management of ectopic pregnancy, Current Opinion Obstet Gynecol, 7, 277-282, 1995
  • 3. Buster, J.E., Carson, S.A., Ectopic pregnancy: new advances in diagnosis and treatment, Current Opinion Obstet Gynecol Scand., 73, 746 - 752, 1994
  • 4. Gleicher, N., Barad, D., Unexplained infertility: does it really exist?, Hum Reprod., 21, 1951-1955, 2006
  • 5. Keay, S.D., Liversedge, N.H., Mathur, R.S. and Jenkins, J.M.Assisted conception following poor ovarian response to gonadotrophin stimulation, Br J Obstet Gynecol., 104, 521-527, 1997
  • 6. Tarlatzis, B.C., Zepiridis, L., Grimbizis, G. and Bontis, J., Clinical management of low ovarian response to stimulation for IVF: a systematic review. Hum Reprod Update, 9, 61-76, 2003
  • 7. Lass, A., Ellenbogen, A., Croucher, C., Trew, G., Margara R., Becattini, C., Winston R.M.L.,Effect of salpingectomy on ovarian response to superovulation in an in vitrofertilization-embryo transfer program, Fertility and Sterility, 70 (6), 1035-1038, 1998
  • 8. Guerriero, S., Ajossa, S., Lai, M.P., Risalvato, A., Paoletti, A.M. and Melis, G.B., Clinical applications of colour Doppler energy imaging in the female reproductive tract and pregnancy, Hum Reprod Update, 5, 515-529, 1999
  • 9. Cooper, J.A., White, D.A., Matthay, R.A., Drug-induced pulmonary disease. Part 1: Cytotoxic drugs, Am Rev Respir Dis., 133, 321-340, 1986
  • 10. Orvieto, IVF cycle following MTX therapy, Fertil Steril, 2007. Article in pres
  • 11. Dar, P., Sachs, G.S., Strassburger, D., Bukovsky, I., Arielli, S., Ovarian function before and after salpinjectomy in artificial reproductive technology patients, Hum Reprod., 15 (1), 142-144, 2000
  • 12. Verhulst, G., Vandersteen, N., Van Steirteghem, A.C., Devroey, P., Bilateral salpingectomy does not compromise ovarian stimulation in an in-vitro fertilization/embryo transfer program, Hum Reprod., 9(4), 624-628, 1994
  • 13. Strandell, A., Lindhard, A.,Waldenstrom, U., Thorburn, J., Prophylactic salpingectomy does not impair the ovarian response in IVF treatment, Hum Reprod., 16(6), 1135-1139, 2001
  • 14. Chan C.C.W. ,.Ng, E.H.Y., Li, C.F. and Ho, P.C., Impaired ovarian blood flow and reduced antral follicle count following laparoscopic salpingectomy for ectopic pregnancy, Human Reproduction., 18(10) 2175-2180, 2003
  • 15. KelekciS., Yilmaz, B., Yakut, Y, Yasar, L., Savan, K., Sonmez, S., Hormonal and ovarian stromal blood supply changes after laparoscopic tubal sterilization: a prospective controlled study, Contraception, 73, 279- 283, 2006
  • 16. Sumiala, S., Pirhonen, J., Tuominen, J. and Maenpaa, J., Increased uterine and ovarian vascular resistance following Filshie clip sterilization: preliminary findings obtained with color Doppler ultrasonography, J. Clin. Ultrasound, 23, 511-516, 1995
  • 17. Geber, S. and Caetano, J.P., Doppler colour flow analysis of uterine and ovarian arteries prior to and after surgery for tubal sterilization: a prospective study, Hum. Reprod., 11, 1195-1198, 1996

Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim

Yıl 2007, Cilt 38, Sayı 4, 143 - 150, 01.05.2007

Öz

Amaç: Laparoskopik salpingostomi ve sistemik tek doz Methotrexate uygulanan hastalarda ovarian fonksiyonlardaki değişimi incelemektir. Gereç ve Yöntem: Bu çalışma Ocak 2005-Temmuz 2007 tarihleri arasında, Ektopikgebelik tanısı ile laparoskopik salpingostomi uygulanan 28 hasta ve 50 mg/m2 tek doz Methotrexate uygulanan 14 hasta dayapılmıştır. Tüm hastalara tedavi öncesi her iki overe ait volüm, antral follikül sayısı ve akım paternlerini değerlendirmek için transvajinal ultrasonografi uygulandı. İstatistiksel analiz için, SPSS for Windows 13.0 paket programı kullanıldı. Bulgular: Laparoskopik salpingostomi uygulanan grupta ortalama yaş 30,6 (-/+ 4,5) iken, Methotrexate uygulanan grupta ise 30,07 (-/+ 3,6) idi (p: 0,68). Hastaların gravida ve pariteleri değerlendirildiğinde sırası ile laparoskopik salpingostomi uygulanan grupta 0,92 (-/+ 1,11), 0,50 (-/+ 0,63) iken; Methotrexate uygulanan grupta ise 0,78 (-/+ 0,8), 0,5 (-/+ 0,65) idi. Sonuç: Elde edilen veriler uygulanan tedavi modalitelerinin (laparoskopik salpingostomi ve sistemik Methotrexate kullanımı) ovarian fonksiyonlar üzerinde olumsuz etkilerinin olmadığını göstermektedir.

Kaynakça

  • 1. Ego, A., Subtil, D., Cosson, M., Legoueff, F.O., Houfflin-Debarge, V.R., Querleu,D., Survival analysis of fertility after ectopic Pregnancy, Fertility and Sterility, 75 (3), 2001
  • 2. Grainger, D.A., Seifer, D.B., Laparoscopic management of ectopic pregnancy, Current Opinion Obstet Gynecol, 7, 277-282, 1995
  • 3. Buster, J.E., Carson, S.A., Ectopic pregnancy: new advances in diagnosis and treatment, Current Opinion Obstet Gynecol Scand., 73, 746 - 752, 1994
  • 4. Gleicher, N., Barad, D., Unexplained infertility: does it really exist?, Hum Reprod., 21, 1951-1955, 2006
  • 5. Keay, S.D., Liversedge, N.H., Mathur, R.S. and Jenkins, J.M.Assisted conception following poor ovarian response to gonadotrophin stimulation, Br J Obstet Gynecol., 104, 521-527, 1997
  • 6. Tarlatzis, B.C., Zepiridis, L., Grimbizis, G. and Bontis, J., Clinical management of low ovarian response to stimulation for IVF: a systematic review. Hum Reprod Update, 9, 61-76, 2003
  • 7. Lass, A., Ellenbogen, A., Croucher, C., Trew, G., Margara R., Becattini, C., Winston R.M.L.,Effect of salpingectomy on ovarian response to superovulation in an in vitrofertilization-embryo transfer program, Fertility and Sterility, 70 (6), 1035-1038, 1998
  • 8. Guerriero, S., Ajossa, S., Lai, M.P., Risalvato, A., Paoletti, A.M. and Melis, G.B., Clinical applications of colour Doppler energy imaging in the female reproductive tract and pregnancy, Hum Reprod Update, 5, 515-529, 1999
  • 9. Cooper, J.A., White, D.A., Matthay, R.A., Drug-induced pulmonary disease. Part 1: Cytotoxic drugs, Am Rev Respir Dis., 133, 321-340, 1986
  • 10. Orvieto, IVF cycle following MTX therapy, Fertil Steril, 2007. Article in pres
  • 11. Dar, P., Sachs, G.S., Strassburger, D., Bukovsky, I., Arielli, S., Ovarian function before and after salpinjectomy in artificial reproductive technology patients, Hum Reprod., 15 (1), 142-144, 2000
  • 12. Verhulst, G., Vandersteen, N., Van Steirteghem, A.C., Devroey, P., Bilateral salpingectomy does not compromise ovarian stimulation in an in-vitro fertilization/embryo transfer program, Hum Reprod., 9(4), 624-628, 1994
  • 13. Strandell, A., Lindhard, A.,Waldenstrom, U., Thorburn, J., Prophylactic salpingectomy does not impair the ovarian response in IVF treatment, Hum Reprod., 16(6), 1135-1139, 2001
  • 14. Chan C.C.W. ,.Ng, E.H.Y., Li, C.F. and Ho, P.C., Impaired ovarian blood flow and reduced antral follicle count following laparoscopic salpingectomy for ectopic pregnancy, Human Reproduction., 18(10) 2175-2180, 2003
  • 15. KelekciS., Yilmaz, B., Yakut, Y, Yasar, L., Savan, K., Sonmez, S., Hormonal and ovarian stromal blood supply changes after laparoscopic tubal sterilization: a prospective controlled study, Contraception, 73, 279- 283, 2006
  • 16. Sumiala, S., Pirhonen, J., Tuominen, J. and Maenpaa, J., Increased uterine and ovarian vascular resistance following Filshie clip sterilization: preliminary findings obtained with color Doppler ultrasonography, J. Clin. Ultrasound, 23, 511-516, 1995
  • 17. Geber, S. and Caetano, J.P., Doppler colour flow analysis of uterine and ovarian arteries prior to and after surgery for tubal sterilization: a prospective study, Hum. Reprod., 11, 1195-1198, 1996

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Namık Kemal DURU Bu kişi benim


Murat MUHCU Bu kişi benim


İbrahim ALANBAY Bu kişi benim


Uğur KESKİN Bu kişi benim


Vedat ATAY Bu kişi benim

Yayımlanma Tarihi 1 Mayıs 2007
Yayınlandığı Sayı Yıl 2007, Cilt 38, Sayı 4

Kaynak Göster

Bibtex @ { zktipb236903, journal = {Zeynep Kamil Tıp Bülteni}, issn = {1300-7971}, eissn = {2148-4864}, address = {}, publisher = {Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH}, year = {2007}, volume = {38}, pages = {143 - 150}, doi = {10.16948/zktb.97915}, title = {Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim}, key = {cite}, author = {Duru, Namık Kemal and Muhcu, Murat and Alanbay, İbrahim and Keskin, Uğur and Atay, Vedat} }
APA Duru, N. K. , Muhcu, M. , Alanbay, İ. , Keskin, U. & Atay, V. (2007). Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim . Zeynep Kamil Tıp Bülteni , 38 (4) , 143-150 . Retrieved from https://dergipark.org.tr/tr/pub/zktipb/issue/22065/236903
MLA Duru, N. K. , Muhcu, M. , Alanbay, İ. , Keskin, U. , Atay, V. "Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim" . Zeynep Kamil Tıp Bülteni 38 (2007 ): 143-150 <https://dergipark.org.tr/tr/pub/zktipb/issue/22065/236903>
Chicago Duru, N. K. , Muhcu, M. , Alanbay, İ. , Keskin, U. , Atay, V. "Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim". Zeynep Kamil Tıp Bülteni 38 (2007 ): 143-150
RIS TY - JOUR T1 - Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim AU - Namık Kemal Duru , Murat Muhcu , İbrahim Alanbay , Uğur Keskin , Vedat Atay Y1 - 2007 PY - 2007 N1 - DO - T2 - Zeynep Kamil Tıp Bülteni JF - Journal JO - JOR SP - 143 EP - 150 VL - 38 IS - 4 SN - 1300-7971-2148-4864 M3 - UR - Y2 - 2021 ER -
EndNote %0 Zeynep Kamil Tıp Bülteni Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim %A Namık Kemal Duru , Murat Muhcu , İbrahim Alanbay , Uğur Keskin , Vedat Atay %T Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim %D 2007 %J Zeynep Kamil Tıp Bülteni %P 1300-7971-2148-4864 %V 38 %N 4 %R %U
ISNAD Duru, Namık Kemal , Muhcu, Murat , Alanbay, İbrahim , Keskin, Uğur , Atay, Vedat . "Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim". Zeynep Kamil Tıp Bülteni 38 / 4 (Mayıs 2007): 143-150 .
AMA Duru N. K. , Muhcu M. , Alanbay İ. , Keskin U. , Atay V. Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim. Zeynep Kamil Tıp Bülteni. 2007; 38(4): 143-150.
Vancouver Duru N. K. , Muhcu M. , Alanbay İ. , Keskin U. , Atay V. Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim. Zeynep Kamil Tıp Bülteni. 2007; 38(4): 143-150.
IEEE N. K. Duru , M. Muhcu , İ. Alanbay , U. Keskin ve V. Atay , "Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim", Zeynep Kamil Tıp Bülteni, c. 38, sayı. 4, ss. 143-150, May. 2007, doi:10.16948/zktb.97915