POSTMENOPOZAL KANAMA İLE BAŞVURAN KADINLARDA ENDOMETRİAL SİTOLOJİ TANI KOYMADA YETERLİ MİDİR?

Dilşad Herkiloğlu; Mustafa Eroğlu; Sadik Şahin; Ahter Tayyar

doi:10.16948/zktipb.416733

Araştırma Makalesi

IN WOMEN WHO APPLY FOR POSTMENOPAUSAL BLEEDING, IS ENDOMETRIAL CYTOLOGY SUFFICIENT TO DIAGNOSE ?

Yıl 2018, Cilt: 49 Sayı: 2, 188 - 191, 27.06.2018

Dilşad Herkiloğlu Mustafa Eroğlu Sadik Şahin Ahter Tayyar

https://doi.org/10.16948/zktipb.416733

Öz

IN WOMEN WHO APPLY
FOR POSTMENOPAUSAL BLEEDING, IS ENDOMETRIAL CYTOLOGY SUFFICIENT TO DIAGNOSE ?

SUMMARY

OBJECTIVE:
Endometrial cancer is the most common invasive neoplasm of the female genital
tract and its incidence has increased in recent years. There is no screening
test for early detection of endometrium carcinoma and its precursors. To
evaluate the safety and comparability of cytologic endometrial samples obtained
with Uterobrush for the diagnosis of endometrial pathologies in women with
postmenopausal bleeding in our study with endometrial biopsy.

METHODS: A total
of 100 patients who were admitted to the gynecological policlinics of our
hospital with postmenopausal bleeding between August 1, 2015 and April 1, 2017
were included in the study. Endoscopic and endometrial sampling were performed
after local anesthesia, cytologic sampling, lithotomy position, and all cases
after local anesthesia. Cytological sampling of endometrium was done by
Uterobrush method. The brush was then taken to the solution for a liquid-based
cytological examination. Endocervical and endometrial curettage was performed
after dilatation.

RESULTS: Our
study also evaluated the feasibility and reliability of endometrial cytology
using the Uterobrush method. Postmenopausal bleeding was observed in 63% (31),
thickening in endometrium (%) and intrauterine fluid in% (6) when 100 patients
were evaluated in terms of USG findings and indications before the procedure.
Brush cytology showed no (94) malignant cells, (3) atrophic cells, (2) ascus
cells and% (1) HGSIL cells in the brush cytology. When brush cytology and probe
curettage (pc) histopathological results were compared, there were no malignant
cells in brush cytology in 2 patients who had PC end result of endometrial
adenocarcinoma. Brush cytology was evaluated as an inactive endometrium of pc
from 2 patients from ascus. The cytology, which is the predominant endometrium,
was also seen as an inactive endometrium in PC.

CONCLUSION:
Uterobrush is a technique used to obtain endometrial cytological specimens. Histological
examination is still used as the gold standard for investigating endometrial
pathology. In our study, endometrial cytological evaluation of Uterobrush
method using endocervical brush was found to be inadequate to diagnose
endometrial pathologies and it was found to be transmitted to cervical cells
during sampling. In the diagnosis of postmenopausal bleeding, probe curettage
uterobrush is the preferred gold standard method.

Anahtar Kelimeler

: Uterobrush, Endometrial sampling

Kaynakça

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